Kits sold directly to consumers to check a variety of health metrics provide little value when it comes to guiding health decisions.
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Bioinformatics software detects cancer-related changes in single-cell studies
In recent years, the analysis of single-cell and spatial data has revolutionized biomedical research, making it possible to observe what happens in biological samples with an unprecedented level of detail. Interpreting this data, however, is not easy because different software offers different results which are hard to compare.
Taking this issue as the starting point, a research group from the University of Trento has developed the “Cell Marker Accordion,” a bioinformatics tool that makes the identification of cell types in the new generation data clearer and more robust. The results of the research, conducted in collaboration with Yale University (United States), the University of Trondheim (Norway), Policlinico di Milano and the Institute of Biophysics of the National Research Council—CNR, are published in Nature Communications.
“With Cell Marker Accordion we wanted to build a tool that helps researchers not only to classify cells, but also to understand why they have been classified in a certain way,” explains Emma Busarello, a Ph.D. candidate in biomolecular sciences at the University of Trento and first author of the work.
Hidden role of ‘cell protector’ opens cancer treatment possibilities
Landmark research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some promising cancer treatments are causing serious side effects, and offers a roadmap for designing safer, more targeted therapies.
The WEHI-led discovery, published in Science, has uncovered a critical new role for MCL-1, revealing it not only prevents cell death but also provides cells with the energy they need to function.
The findings reshape our understanding of how cells survive and thrive, with implications for both cancer treatment and developmental biology.
Is Earth inside a huge void? ‘Sound of the Big Bang’ hints at possible solution to Hubble tension
Earth and our entire Milky Way galaxy may sit inside a mysterious giant hole which makes the cosmos expand faster here than in neighboring regions of the universe, astronomers say.
Their theory is a potential solution to the “Hubble tension” and could help confirm the true age of our universe, which is estimated to be around 13.8 billion years old.
The latest research —shared at the Royal Astronomical Society’s National Astronomy Meeting (NAM 2025) at Durham University—shows that sound waves from the early universe, “essentially the sound of the Big Bang,” support this idea.
Meteorite challenges the timeline of the early solar system
A small, inconspicuous meteorite may be about to change our understanding of how and when our solar system formed. Tiny shavings from the meteorite Northwest Africa 12264 are challenging the long-held belief that planets near the sun formed earlier than those beyond the asteroid belt, between Mars and Jupiter.