Lifeboat Foundation

Basically this means halting and controlling cellular death which would reverse the death process :3.

During pyroptosis, gasdermin D (GSDMD) forms plasma membrane pores that initiate cell lysis. Here, the authors develop optogenetically activatable human GSDMD to assess GSDMD pore behavior and show that they are dynamic and can close, which can be a pyroptosis regulatory mechanism.

In recent years, deep learning algorithms have achieved remarkable results in a variety of fields, including artistic disciplines. In fact, many computer scientists worldwide have successfully developed models that can create artistic works, including poems, paintings and sketches.

Researchers at Seoul National University have recently introduced a new artistic deep learning framework, which is designed to enhance the skills of a sketching robot. Their framework, introduced in a paper presented at ICRA 2022 and pre-published on arXiv, allows a sketching robot to learn both stroke-based rendering and motor control simultaneously.

Continue reading “A deep learning framework to enhance the capabilities of a robotic sketching agent” »

The lead in some bullets used for hunting deer, moose, and elk is toxic to the humans who eat the harvested meat and to scavenger animals that feast on remains left in the field.

A team of researchers from the Canadian Light Source at the University of Saskatchewan (USask) and the College of Medicine at USask has for the first time used synchrotron imaging to study both the size and spread of bullet fragments in big game shot by hunters. Their findings were published today in PLOS ONE.

Continue reading “New research on the risks of lead exposure from bullets used in big game hunting” »

Researchers from RIKEN in Japan have achieved a major step toward large-scale quantum computing by demonstrating error correction in a three-qubit silicon-based quantum computing system. This work, published in Nature, could pave the way toward the achievement of practical quantum computers.

Quantum computers are a hot area of research today, as they promise to make it possible to solve certain important problems that are intractable using conventional computers. They use a completely different architecture, using superimposition states found in quantum physics rather than the simple 1 or 0 binary bits used in conventional computers. However, because they are designed in a completely different way, they are very sensitive to environmental noise and other issues, such as decoherence, and require error correction to allow them to do precise calculations.

One important challenge today is choosing what systems can best act as “qubits”—the basic units used to make quantum calculations. Different candidate systems have their own strengths and weaknesses. Some of the popular systems today include superconducting circuits and ions, which have the advantage that some form of error correction has been demonstrated, allowing them to be put into actual use albeit on a small scale. Silicon-based quantum technology, which has only begun to be developed over the past decade, is known to have an advantage in that it utilizes a semiconductor nanostructure similar to what is commonly used to integrate billions of transistors in a small chip, and therefore could take advantage of current production technology.

Someone taps your shoulder. The organized touch receptors in your skin send a message to your brain, which processes the information and directs you to look left, in the direction of the tap. Now, Penn State and U.S. Air Force researchers have harnessed this processing of mechanical information and integrated it into engineered materials that “think”.

The work, published today in Nature, hinges on a novel, reconfigurable alternative to integrated circuits. Integrated circuits are typically composed of multiple electronic components housed on a single semiconductor material, usually silicon, and they run all types of modern electronics, including phones, cars and robots. Integrated circuits are scientists’ realization of information processing similar to the brain’s role in the human body. According to principal investigator Ryan Harne, James F. Will Career Development Associate Professor of Mechanical Engineering at Penn State, integrated circuits are the core constituent needed for scalable computing of signals and information but have never before been realized by scientists in any composition other than silicon semiconductors.

Continue reading “Researchers engineer novel material capable of ‘thinking’” »

MIT researchers unveil the first open-source simulation engine capable of constructing realistic environments for deployable training and testing of autonomous vehicles. Since they’ve proven to be productive test beds for safely trying out dangerous driving scenarios, hyper-realistic virtual worlds have been heralded as the best driving schools for autonomous vehicles (AVs). Tesla, Waymo, and other self-driving companies all rely heavily on data to enable expensive and proprietary photorealistic simulators, because testing and gathering nuanced I-almost-crashed data usually isn’t the easiest or most desirable to recreate.

The human dorsolateral prefrontal cortex is involved in cognitive control including attention selection, working memory, decision making and planning of actions. Changes in this brain region are suspected to play a role in schizophrenia, obsessive-compulsive disorder, depression and bipolar disorder, making it an important research target. Researchers from Forschungszentrum Jülich and Heinrich-Heine University Düsseldorf now provide detailed, three-dimensional maps of four new areas of the brain region.

In order to identify the borders between brain areas, the researchers statistically analysed the distribution of cells (the cytoarchitecture) in 10 post mortem human brains. After reconstructing the mapped areas in 3D, the researchers superimposed the maps of the 10 different brains and generated probability maps that reflect how much the localization and size of each area varies among individuals.

High inter-subject variability has been a major challenge for prior attempts to map this brain region leading to considerable discrepancies in pre-existing maps and inconclusive information making it very difficult to understand the specific involvement of individual brain areas in the different cognitive functions. The new probabilistic maps account for the variability between individuals and can be directly superimposed with datasets from functional studies in order to directly correlate structure and function of the areas.

Trains that run on hydrogen.

Re-sharing.

(CNN) — The future of environmentally friendly travel might just be here — and it’s Germany that’s leading the charge, with the first ever rail line to be entirely run on hydrogen-powered trains, starting from Wednesday.

Continue reading “The world’s first hydrogen-powered passenger trains are here” »

The journey of half a million miles – the first flight of the Artemis Generation – is about to begin. The uncrewed Artemis I mission will jump-start humanity’s return to the Moon with the thunderous liftoff of NASA’s powerful new Space Launch System rocket and Orion spacecraft. This critical flight test will send Orion farther than any human-rated spacecraft has ever flown, putting new systems and processes to the test and lighting the way for the crew missions to come. Artemis I is ready for departure – and, together with our partners around the world, we are ready to return to the Moon, with our sights on Mars and beyond.

Producer: lisa allen, barbara zelon, alysia lee. writer & director: paul wizikowski