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Scientists already have their ways of coaxing human cells into new forms, using a special concoction of chemicals to nudge humble skin cells into malleable tissues known as induced pluripotent stem cells.

In spite of this new lease on life, these particular cells still retain a few genetic reminders of their time as a fully developed tissue, affecting their use as a blank slate.

Now an international team of researchers has gone one better: finding a new way of wiping a cell’s memory clean so it can be better reprogrammed as a stem cell.

A new VTOL firm promises to make flying cars a reality, but unlike many similar firms, this one has a NASA-proven design at its heart.

Simple heterojunction combines many functions in a single component.

Stem cells in organoids self-organize into tissue patterns with unknown mechanisms. Here, we use skin organoids to analyze this process. Cell behavior videos show that the morphological transformation from multiple spheroidal units with morphogenesis competence (CMU) to planar skin is characterized by two abrupt cell motility–increasing events before calming down. The self-organizing processes are controlled by a morphogenetic module composed of molecular sensors, modulators, and executers. Increasing dermal stiffness provides the initial driving force (driver) which activates Yap1 (sensor) in epidermal cysts. Notch signaling (modulator 1) in epidermal cyst tunes the threshold of Yap1 activation. Activated Yap1 induces Wnts and MMPs (epidermal executers) in basal cells to facilitate cellular flows, allowing epidermal cells to protrude out from the CMU. Dermal cell–expressed Rock (dermal executer) generates a stiff force bridge between two CMU and accelerates tissue mixing via activating Laminin and β1-integrin. Thus, this self-organizing coalescence process is controlled by a mechano-chemical circuit. Beyond skin, self-organization in organoids may use similar mechano-chemical circuit structures.

Aude Oliva is a prominent Cognitive and Computer Scientist directing the MIT Computational Perception and Cognition group at CSAIL while also leading the MIT-IBM Watson AI Lab and co-leading the MIT AI Hardware Program. With research spanning computational neuroscience, cognition, and computer vision, she pioneers the integration of human perception and machine recognition. Her contributions extend across academia, industry, and research, making her a distinguished figure at MIT.

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Construction is set to break ground by the end of this year, and the company expects to move into the new space by the end of 2024. The production facility for semiconductor quartz will include a clean room, high-purity cleaning system and allow them to expand an automation component of their business that they’ve been capitalizing on for years.

“We knew that our customers all over the world were expanding at a rate we couldn’t keep up with,” said Scott Lingren, SXT’s managing director and U.S. chairman. “As you see all these expansions from Samsung in Taylor to Texas Instruments Inc. in the Dallas area to all over the world … we just have to keep up.”

SXT – which is headquartered in the Netherlands and owned by the privately-held Schunk Group in Germany – supplies semiconductor manufacturers around the world, like Samsung, which has had a presence in Central Texas for decades and is potentially adding to its existing Austin campus and its new site in Taylor. Other major players in the industry include Taiwan Semiconductor Manufacturing Co., which is expanding in Arizona, and Intel Corp., which is expanding to Ohio.

GM’s self-driving robotaxi unit, Cruise, is poised to deploy a small fleet of autonomous cars in Seattle, Washington. The initial deployment of the vehicles will reportedly include safety drivers.

Cruise’s deployment in the city will begin in sections of downtown Seattle, Capitol Hill, Queen Anne, Fremont, the University District, and West Seattle. From this, Cruise would be able to collect valuable real-world data. The robotaxi provider would be joining other self-driving units that are also operating in Seattle today, such as Zoox.

In a comment to Geek Wire, Cruise executive VP of engineering Mohamed Elshenawy noted that Seattle would be a great testing ground for the company’s self-driving robotaxis. The city, after all, features hilly areas and inclement weather conditions, which should present Cruise with some interesting edge cases and challenges.

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Hello and welcome! My name is Anton and in this video, we will talk about bizarre quantum effects discovered in the last few months.
Links:
https://news.uchicago.edu/story/uchicago-scientists-observe-…laboratory.
https://www.nature.com/articles/s41567-023-02139-8
https://www.nature.com/articles/s41586-023-05727-z.
https://www.nature.com/articles/s42005-022-00881-8
#quantum #quantumphysics #quantummechanics.

0:00 Evidence for quantum superchemistry.
3:40 Solar fusion is quantum and not classical.
5:20 Quantum tunneling and microscopy.
7:00 Tunneling causes chemistry.
7:40 Tunneling affects DNA and causes mutation.

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