Lifeboat Foundation: Safeguarding Humanity
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It is widely recognized that continuously scaling both data size and model size can lead to significant improvements in model intelligence. However, the research and industry community has limited experience in effectively scaling extremely large models, whether they are dense or Mixture-of-Expert (MoE) models. Many critical details regarding this scaling process were only disclosed with the recent release of DeepSeek V3. Concurrently, we are developing, a large-scale MoE model that has been pretrained on over 20 trillion tokens and further post-trained with curated Supervised Fine-Tuning (SFT) and Reinforcement Learning from Human Feedback (RLHF) methodologies. Today, we are excited to share the performance results of and announce the availability of its API through Alibaba Cloud. We also invite you to explore on Qwen Chat!

We evaluate alongside leading models, whether proprietary or open-weight, across a range of benchmarks that are of significant interest to the community. These include MMLU-Pro, which tests knowledge through college-level problems, LiveCodeBench, which assesses coding capabilities, LiveBench, which comprehensively tests the general capabilities, and Arena-Hard, which approximates human preferences. Our findings include the performance scores for both base models and instruct models.

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An AI model created to design proteins simulates 500 million years of protein evolution in developing a previously unknown bright fluorescent protein.

Learn more in a new Science study.

More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can generate functional proteins that are far away from known proteins. We present ESM3, a frontier multimodal generative language model that reasons over the sequence, structure, and function of proteins. ESM3 can follow complex prompts combining its modalities and is highly responsive to alignment to improve its fidelity. We have prompted ESM3 to generate fluorescent proteins. Among the generations that we synthesized, we found a bright fluorescent protein at a far distance (58% sequence identity) from known fluorescent proteins, which we estimate is equivalent to simulating five hundred million years of evolution.

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A study led by researchers from the University of Virginia has used satellite measurements to show the long-term persistence of air pollution inequalities tied to industrialized swine facilities in Eastern North Carolina.

Using spanning a 15-year period from 2008–2023, the study quantifies disparities in ammonia (NH3)—an air pollutant emitted by swine operations—for Black, Hispanic and Indigenous communities. These inequalities, exacerbated by hot and calm weather conditions, extend for multiple kilometers beyond the immediate vicinity of the facilities, highlighting the widespread impact of this environmental issue.

The study, published in Environmental Science & Technology by Sally Pusede and her team in the Department of Environmental Sciences at UVA, uses data from the Infrared Atmospheric Sounding Interferometer (IASI) aboard multiple polar-orbiting satellites. By analyzing NH3 levels in the atmosphere, UVA researchers were able to show that emissions from industrial swine operations result in systematic environmental inequalities.

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In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and Intelligence Technology of the Chinese Academy of Sciences (CAS), along with Li Yang from the Shanghai Institute of Materia Medica of CAS, has dissected the assembly and architecture of endogenous N-methyl-ᴅ-aspartate receptors (eNMDARs) in the adult mammalian cerebral cortex and hippocampus.

Learning and memory are fundamental brain functions that underlie and perception of the world, which rely on development-and activity-dependent synaptic plasticity. NMDA receptors, members of the excitatory ionotropic glutamate receptor family, are essential to these processes.

They regulate the strength of synaptic connections, playing a critical role in advanced brain functions. In higher brain structures involved in cognition, such as the cerebral cortex and hippocampus, they are especially vital for cognitive function.

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New Shepard is a rocket manufactured by Blue Origin for space tourism, however the newest mission will be simulating the Moon’s gravity and flying 30 payloads to test lunar related technology. \r.

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You can watch the action live here or at Space.com!

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On the positive side, some human entrepreneurs could become very wealthy, possibly trillionaires if they could tap into these AI’s wealth somehow. Additionally, super rich AIs could be a solution to the United States’ growing debt crisis, and eliminate the need for whether countries like China can continue to buy our debt so we can indefinitely print dollars. In fact, can America launch its own AI agents to create enough crypto wealth to buy its debt?

Naturally, the risk is that these AIs might eventually try to buy other financial instruments, like existing bonds and stocks. But it’s unlikely they’d be able to do so, unless more of the U.S.’ economy went into crypto and became blockchain based. Additionally, AI bots aren’t allowed to have traditional bank accounts yet.

Whatever happens, clearly there is an urgent need for the U.S. government to address such potentialities. Given that these AIs could start to proliferate in the next few months, I suggest Congress and the Trump administration immediately convene a special task force to specifically tackle the possibility of an AI Monetary Hegemony.

The real danger is that even with regulation, programmers will still be able to release autonomous AIs into the wild—just as many illegal things already happen on the web despite the existence of laws. Programmers might release these types of AIs for kicks, while others try to profit from it—and some may even do so even as a form of terrorism to try to hamper the world economy. Whatever the reason, the creation of autonomous AIs will soon be a reality of life. And vigilance and foresight will be needed as these new AIs start to autonomously disrupt our financial future.

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A new Tulane University study suggests the Mediterranean diet’s brain-boosting benefits may work by changing the balance of bacteria in the gut.

In a study published in Gut Microbes Reports, researchers at Tulane University School of Medicine found that subjects following a Mediterranean diet developed distinctly different gut bacteria patterns compared to those eating a typical Western diet. These bacterial changes correlated with better memory and cognitive performance.

“We’ve known that what we eat affects brain function, but this study explores how that could be happening,” said lead author Rebecca Solch-Ottaiano, Ph.D., neurology research instructor at Tulane’s Clinical Neuroscience Research Center. “Our findings suggest that dietary choices can influence cognitive performance by reshaping the gut microbiome.”

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