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Aging is a natural part of life and yet one most of us hope to delay. At a certain point when you start feeling the effects of age and want the whole process to stop rushing forward. But can aging really be slowed down?

A growing body of work paints a fuller picture of the search for the elixir of youth, looking in particular at changes happening at the molecular and cellular levels. Interesting Engineering spoke with Dr. Miglė Tomkuvienė, a biochemist at Vilnius University, whose new article addresses this very question — is it possible to delay old age?

Metal halide perovskites, a class of crystalline materials with remarkable optoelectronic properties, have proven to be promising candidates for the development of cost-effective thin-film transistors. Recent studies have successfully used these materials, particularly tin (Sn) halide perovskites, to fabricate p-type transistors with field-effect hole mobilities (μh) of over 70 cm2 V−1 s−1.

1I/2017 U1 (‘Oumuamua) was discovered in October 2017; shortly after, it was determined to be the first object ever seen inside the solar system that had come from beyond it. But by the time its origins had been discerned, the interstellar interloper had already rounded the Sun and was speeding away at some 85,700 mph (138,000 km/h). Just an estimated 1,300 feet (400 meters) across, it faded from view of even the most powerful telescopes within weeks.

The only way to gather more data and uncover its true nature would be to send a spacecraft to study it up close. But uncertainties in ‘Oumuamua’s exact trajectory, the difficulty of detecting its ever-dimming light, and its rapid retreat make the idea of designing, building, and launching a mission in time to catch up to it seem utterly impossible.

NVIDIA today announced that the world’s 28 million developers can now download NVIDIA NIM™ — inference microservices that provide models as optimized containers — to deploy on clouds, data centers or workstations, giving them the ability to easily build generative AI applications for copilots, chatbots and more, in minutes rather than weeks.

The space agency has been around since 1958, yet only a select few spacecraft have transported NASA astronauts to space. Boeing’s Starliner could join a rather exclusive list should it succeed in docking with the ISS and delivering its precious human cargo. We’ve put together a list of all the spacecraft that have flown, or will soon be flown, with NASA crews on board.

Researchers based at the Dept of Biology and School of Physics, Engineering and Technology have developed a remarkable new technology which is able to study single biological molecules using intrinsic twist properties to bring about essential functions in cells.

“Nano twists” that drive life

There are myriad so-called “chiral” molecules in biology, which have a fascinating property of not appearing to have the same structure were you to look at their image in a mirror — one of the best known examples being DNA, the “molecule of life”, whose chirality comes from its amazing double helix structure. This chirality, which looks in the case of extended DNA molecules like “nano twists”, results in a property which physicists describe as “symmetry breaking” which in turn can drive molecules into a range of different states. With input from sources of energy, these molecules can then jump between different states as part of their normal function, and it is this state jumping which essentially drives all processes in living cells — so chirality is an enormously fundamental feature which in effect effect steers key cellular processes.

Differential neuromorphic computing, as a memristor-assisted perception method, holds the potential to enhance subsequent decision-making and control processes. Compared with conventional technologies, both the PID control approach and the proposed differential neuromorphic computing share a fundamental principle of smartly adjusting outputs in response to feedback, they diverge significantly in the data manipulation process (Supplementary Discussion 12 and Fig. S26); our method leverages the nonlinear characteristics of the memristor and a dynamic selection scheme to execute more complex data manipulation than linear coefficient-based error correction in PID. Additionally, the intrinsic memory function of memristors in our system enables real-time adaptation to changing environments. This represents a significant advantage compared to the static parameter configuration of PID systems. To perform similar adaptive control functions in tactile experiments, the von Neumann architecture follows a multi-step process involving several data movements: 1. Input data about the piezoresistive film state is transferred to the system memory via an I/O interface. 2. This sensory data is then moved from the memory to the cache. 3. Subsequently, it is forwarded to the Arithmetic Logic Unit (ALU) and waits for processing.4. Historical tactile information is also transferred from the memory to the cache unless it is already present. 5. This historical data is forwarded to the ALU. 6. ALU calculates the current sensory and historical data and returns the updated historical data to the cache. In contrast, our memristor-based approach simplifies this process, reducing it to three primary steps: 1. ADC reads data from the piezoresistive film. 2. ADC reads the current state of the memristor, which represents the historical tactile stimuli. 3. DAC, controlled by FPGA logic, updates the memristor state based on the inputs. This process reduces the costs of operation and enhances data processing efficiency.

In real-world settings, robotic tactile systems are required to elaborate large amounts of tactile data and respond as quickly as possible, taking less than 100 ms, similar to human tactile systems58,59. The current state-of-the-art robotics tactile technologies are capable of elaborating sudden changes in force, such as slip detection, at millisecond levels (from 500 μs to 50 ms)59,60,61,62, and the response time of our tactile system has also reached this detection level. For the visual processing, suppose a vehicle travels 40 km per hour in an urban area and wants control effective for every 1 m. In that case, the requirement translates a maximum allowable response time of 90 ms for the entire processing pipeline, which includes sensors, operating systems, middleware, and applications such as object detection, prediction, and vehicle control63,64. When incorporating our proposed memristor-assisted method with conventional camera systems, the additional time delay includes the delay from filter circuits (less than 1 ms) and the switching time for the memristor device, which ranges from nanoseconds (ns) to even picoseconds (ps)21,65,66,67. Compared to the required overall response time of the pipeline, these additions are negligible, demonstrating the potential of our method application in real-world driving scenarios68. Although our memristor-based perception method meets the response time requirement for described scenarios, our approach faces several challenges that need to be addressed for real-world applications. Apart from the common issues such as variability in device performance and the nonlinear dynamics of memristive responses, our approach needs to overcome the following challenges:

Currently, the modulation voltage applied to memristors is preset based on the external sensory feature, and the control algorithm is based on hard threshold comparison. This setting lacks the flexibility required for diverse real-world environments where sensory inputs and required responses can vary significantly. Therefore, it is crucial to develop a more automatic memristive modulation method along with a control algorithm that can dynamically adjust based on varying application scenarios.