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Oh, the logic of objections against rejuvenation! bigsmile

If you’ve ever tried to advocate for rejuvenation, you know it is hard. Usually, people deem the idea as crazy/impossible/dangerous well before you get to finish your first sentence. Living too long would be boring, it would cause overpopulation, ‘immortal’ dictators, and what you have. However, you’ve probably never heard anyone use the same arguments to say that we should not cure individual age-related diseases. This is largely because people have little to no idea about what ageing really is, and how it cannot be untangled from the so-called age-related pathologies. These are nothing more, nothing less, than the result of the life-long accumulation of several types of damage caused by the body’s normal operations. Unlike infectious diseases, the diseases of old age are not the result of a pathogen attack, but essentially of your own body falling apart. As I was saying, people are largely unaware of this fact, and therefore expect that the diseases of ageing could be cured one by one without having to interfere with the ageing process itself, as if the two weren’t related at all. The result of this false expectation would be that you could cure Alzheimer’s, Parkinson’s, etc., but somehow old people would still drop dead around the age of 80 just because they’re old. That’s like saying they died of being healthy.

Back to reality, this can’t be done. To cure the diseases of old age, you need to cure ageing itself. If, for whatever reason, you think that curing ageing as a whole would be a bad idea and it should not be done, the only option is to not cure at least some of the root causes of ageing. Consequently, some age-related pathologies would remain as untreatable as they are today.

Now, the typical objections raised against rejuvenation tend to sound reasonable at first. To some, the statement ‘We should not cure ageing because it would lead to overpopulation’ sounds self-evident. However, if we consider the implications of this statement, things start getting crazy. As said, not curing ageing implies not curing some of its root causes, which in turn implies not curing some age-related diseases. Therefore, the sentence ‘We should not cure ageing’ implies ‘We should not cure [insert age-related disease here] ‘. What happens when we reformulate typical objections to rejuvenation in this fashion?

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I really wanna know why people don’t get this.

For more information on Aubrey de Grey, please visit our website www.tedxmuenchen.de

Dr. Aubrey de Grey is a biomedical gerontologist based Mountain View, California, USA, and is the Chief Science Officer of SENS Research Foundation, a California-based 501©(3) biomedical research charity that performs and funds laboratory research dedicated to combating the aging process. He is also Editor-in-Chief of Rejuvenation Research, the world’s highest-impact peer-reviewed journal focused on intervention in aging. He received his BA in computer science and Ph.D. in biology from the University of Cambridge. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism (“damage”) that constitute mammalian aging and the design of interventions to repair and/or obviate that damage.

Continue reading “How we can finally win the fight against aging” | >

Today, spectrum is managed by dividing it into rigid, exclusively licensed bands. This human-driven process is not adaptive to the dynamics of supply and demand, and thus cannot exploit the full potential capacity of the spectrum. In SC2, competitors will reimagine a new, more efficient wireless paradigm in which radio networks autonomously collaborate to dynamically determine how the spectrum should be used moment to moment.

The team whose radio design most reliably achieves successful communication in the presence of other competing radios could win as much as $3,500,000. For more information, see the About Page.

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Scientists at the Salk Institute have found that intermittent expression of genes normally associated with an embryonic state can reverse the hallmarks of old age. This approach, which not only prompted human skin cells in a dish to look and behave young again, also resulted in the rejuvenation of mice with a premature aging disease, countering signs of aging and increasing the animals’ lifespan by 30 percent. The early-stage work provides insight both into the cellular drivers of aging and possible therapeutic approaches for improving human health and longevity.

Turning back time: Salk scientists reverse signs of aging

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California’s Department of Motor Vehicles released its annual autonomous vehicle disengagement report today, in which all the companies that are actively testing self-driving cars on public roads in the Golden State disclose the number of times that human drivers were forced to take control of their driverless vehicles. The biggest news to come out of this report is from Waymo, Google’s new self-driving car company, which reported a huge drop in disengagements in 2016 despite an almost equally huge increase in the number of miles driven.

In other words, Waymo’s self-driving cars are failing at a much lower rate, even as they are driving a whole lot more miles. The company says that since 2015, its rate of safety-related disengages has fallen from 0.8 per thousand miles to 0.2 per thousand miles in 2016. So while Waymo increased its driving by 50 percent in the state — racking up a total of 635,868 miles — the company’s total number of reportable disengages fell from 341 in 2015 to 124.

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