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Results of DNA studies also seem to confirm the idea that optimism is an effective tool for slowing down cellular aging, of which telomere shortening is a biomarker. (Telomeres are the protective caps at the end of our chromosomes.) This research is still in progress, but the early results are informative. In 2012, Elizabeth Blackburn, who three years earlier shared a Nobel Prize for her work in discovering the enzyme that replenishes the telomere, and Elissa Epel at the University of California at San Francisco, in collaboration with other institutions, identified a correlation between pessimism and accelerated telomere shortening in a group of postmenopausal women. A pessimistic attitude, they found, may indeed be associated with shorter telomeres. Studies are moving toward larger sample sizes, but it already seems apparent that optimism and pessimism play a significant role in our health as well as in the rate of cellular senescence. More recently, in 2021, Harvard University scientists, in collaboration with Boston University and the Ospedale Maggiore in Milan, Italy, observed the telomeres of 490 elderly men in the Normative Health Study on U.S. veterans. Subjects with strongly pessimistic attitudes were associated with shorter telomeres — a further encouraging finding in the study of those mechanisms that make optimism and pessimism biologically relevant.

Optimism is thought to be genetically determined for only 25 percent of the population. For the rest, it’s the result of our social relationships or deliberate efforts to learn more positive thinking. In an interview with Jane Brody for the New York Times, Rozanski explained that “our way of thinking is habitual, unaware, so the first step is to learn to control ourselves when negative thoughts assail us and commit ourselves to change the way we look at things. We must recognize that our way of thinking is not necessarily the only way of looking at a situation. This thought alone can lower the toxic effect of negativity.” For Rozanski, optimism, like a muscle, can be trained to become stronger through positivity and gratitude, in order to replace an irrational negative thought with a positive and more reasonable one.

While the exact mechanisms remain under investigation, a growing body of research suggests that optimism plays a significant role in promoting both physical and mental well-being. Cultivating a positive outlook, then, can be a powerful tool for fostering resilience, managing stress, and potentially even enhancing longevity. By adopting practices that nurture optimism, we can empower ourselves to navigate life’s challenges with greater strength and live healthier, happier lives.

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EMPs aren’t science fiction. Real militaries are experimenting on real EMP generators, and as Starfish Prime showed us, space nukes can send powerful EMPs to the surface. So what exactly is an EMP, and how dangerous are they?

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“More testing, a purification system and approval from the U.S. Food and Drug Administration would be needed to put the strategy to work. But insulin produced by transgenic cows could ease shortages that often make the hormone hard to come by for the 8.4 million Americans with diabetes who rely on it to survive.”


MONDAY, March 18, 2024 (HealthDay News) — There may be an unexpected fix for ongoing shortages of insulin: A brown bovine in Brazil recently made history as the first transgenic cow able to produce human insulin in her milk.

Researchers at the National University of Singapore (NUS) have developed an innovative method for creating carbon-based quantum materials atom by atom. This method combines the use of scanning probe microscopy with advanced deep neural networks. The achievement underlines the capabilities of artificial intelligence (AI) in manipulating materials at the sub-angstrom level, offering significant advantages for basic science and potential future uses.

Open-shell magnetic nanographenes represent a technologically appealing class of new carbon-based quantum materials, which host robust π-spin centers and non-trivial collective quantum magnetism. These properties are crucial for developing high-speed electronic devices at the molecular level and creating quantum bits, the building blocks of quantum computers.

Despite significant advancements in the synthesis of these materials through on-surface synthesis, a type of solid-phase chemical reaction, achieving precise fabrication and tailoring of the properties of these quantum materials at the atomic level has remained a challenge.

How deep is the lunar regolith and megaregolith, the latter of which consists of the cracked lunar crust layers resulting from billions of years of impact craters? This is what the Synthetic Pulse Artemis Radar for Crustal Imaging (SPARCI, pronounced “sparky”) instrument hopes to address as the Southwest Research Institute (SwRI) was recently awarded a 3-year, $2,041,000 grant from NASA’s Development and Advancement of Lunar Instrumentation (DALI) program as part of advancing lunar exploration technologies.

Image of the Synthetic Pulse Artemis Radar for Crustal Imaging (SPARCI, pronounced “sparky”). (Credit: Southwest Research Institute/Bryan Pyke)

“Learning more about the lunar megaregolith will help us gain a wider understanding of the Moon’s formation and that of similar bodies with thin, sparse atmospheres,” said Dr. David Stillman, who is a geophysicist at SwRI and SPARCI’s principal investigator. “If we are able to pinpoint exactly where this layer begins, we can use that to create more accurate formation and evolution models.”

With the continued advancement of human space exploration, how can forensic science—which contributes to the criminal justice system by analyzing evidence through a myriad of methods—be applied to outer space? This is what a soon-to-be-published study in Forensic Science International Reports hopes to address as a team of international researchers led by Staffordshire University investigated how bloodstain patterns behave under microgravity conditions. This study holds the potential to help scientists and astronauts better understand how Earth-based science can be applied to space, specifically long-term spaceflight.

“Studying bloodstain patterns can provide valuable reconstructive information about a crime or accident,” said Zack Kowalske, who is a PhD student at Staffordshire University and a Crime Scene Investigator for the Roswell Police Department in the State of Georgia, and lead author of the study. “However, little is known about how liquid blood behaves in an altered gravity environment. This is an area of study that, while novel, has implications for forensic investigations in space.”

For the study, the researchers conducted blood spatters experiments on parabolic flights onboard a modified Boeing 747 with an emphasis on observing various angles of impact of the blood droplets and comparing their splatter patterns to those obtained under normal gravity conditions. The reason parabolic flights were used was due to their ability to simulate microgravity conditions, as they are designed to rapidly drop in altitude, thus providing passengers with a few moments of weightlessness.

H/T Stephen Wolfram.

Particularly given its recent surprise successes, there’s a somewhat widespread belief that eventually AI will be able to “do everything”, or at least everything we currently do.


Stephen Wolfram explores the potential—and limitations—of AI in science. See cases in which AI will be a useful tool, and in others a less ideal tool.

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This year, Rockefeller scientists plumbed the depths of wound repair and tackled how songbirds solve problems; they used microchips to grow mini-lungs and proposed an environmental trigger for multiple sclerosis. Efforts to combat COVID, Hepatitis B, and other infections bore fruit, and countless papers shed light on basic research, answering questions that have long baffled biologists. Here are some of the intriguing discoveries that came out of Rockefeller in 2023.

Old sperm, new mutations

As the male reproductive system ages, it becomes more and more susceptible to mutations. New research from the laboratory of Li Zhao explored this phenomenon in fruit flies, by focusing on how mutations arise during the formation of sperm. The team found that, while mutations are common in the testes of both young and old flies, the repair mechanisms that remove those mutations and maintain genomic integrity during spermatogenesis become less efficient in older individuals, leading to the accumulation and persistence of more mutations in older flies.

Argonne’s Science 101 series takes you back to the basics, with plain-language explanations of the scientific concepts behind our pivotal discoveries and our biggest innovations.

In this Science 101 video, postdoctoral researchers Gillian Beltz-Mohrmann and Florian Kéruzoré explore two of the biggest mysteries in science: dark matter and dark energy. These strange influences seem to be stretching the universe apart and clumping stuff together in unexpected ways. Together, they make up a whopping 95% of the universe, but because we can’t see or touch them, we don’t know what they are.

Researchers around the globe, including scientists at the U.S. Department of Energy’s Argonne National Laboratory, are investigating the nature of dark matter and dark energy through large cosmological surveys, particle physics experiments and advanced computing and simulation.

Find out more about Argonne Science 101 ►► https://www.anl.gov/science-101