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Multisynapse optical network outperforms digital AI models

For decades, scientists have looked to light as a way to speed up computing. Photonic neural networks—systems that use light instead of electricity to process information—promise faster speeds and lower energy use than traditional electronics.

But despite their potential, these systems have struggled to match the accuracy of digital . A key reason: most photonic systems still mimic the structure and training methods of digital models, introducing errors when translating from software to hardware.

Now, a research team from Northwestern Polytechnical University and Southeast University in China has developed a new kind of photonic neural network that breaks free from this digital imitation. Their design, published in Advanced Photonics Nexus, uses physical transformations of light to process information directly, without relying on mathematical models. This approach not only improves accuracy but also highlights a new direction for building smarter, faster AI hardware.

Novel AI method sheds light on how enzyme linked to Alzheimer’s selects its targets

Researchers from DZNE, Ludwig-Maximilians-Universität München (LMU), and Technical University of Munich (TUM) have found that the enzyme “gamma-secretase”—implicated in Alzheimer’s disease and cancer—selects its reaction partners according to a complex scheme of molecular features.

Their study, published in Nature Communications, introduces a methodology that decodes the enzyme’s recognition logic by bridging biochemistry with explainable artificial intelligence (AI). This novel approach could help to better understand the role of in diseases and aid drug development.

Gamma-secretase is an enzyme belonging to the category of “proteases” that plays a key role in Alzheimer’s disease and cancer. It occurs in the membrane of numerous cells, including neurons, where—acting like a pair of scissors—it cleaves other membrane-bound proteins.

Robot performs 1st realistic surgery without human help

A robot trained on videos of surgeries performed a lengthy phase of a gallbladder removal without human help. The robot operated for the first time on a lifelike patient, and during the operation, responded to and learned from voice commands from the team—like a novice surgeon working with a mentor.

The robot performed unflappably across trials and with the expertise of a skilled human surgeon, even during unexpected scenarios typical in real life medical emergencies.

The federally-funded work, led by Johns Hopkins University researchers, is a transformative advancement in surgical robotics, where robots can perform with both mechanical precision and human-like adaptability and understanding.

“This advancement moves us from robots that can execute specific surgical tasks to robots that truly understand surgical procedures,” said medical roboticist Axel Krieger. “This is a critical distinction that brings us significantly closer to clinically viable autonomous surgical systems that can work in the messy, unpredictable reality of actual patient care.”

Practical changes could reduce AI energy demand by up to 90%

Artificial intelligence (AI) can be made more sustainable by making practical changes, such as reducing the number of decimal places used in AI models, shortening responses, and using smaller AI models, according to research from UCL published in a new UNESCO report.

In recent years, the use of generative AI has expanded rapidly, with (LLMs) developed by companies such as OpenAI, Meta and Google becoming household names. For example, OpenAI’s ChatGPT service, powered by the GPT-4 LLM, receives about 1 billion queries each day.

Each generation of LLMs has become more sophisticated than the last, better able to perform tasks like text generation or knowledge retrieval. This has led to a vast and increasing demand on resources such as electricity and water, which are needed to run the data centers where these AI models are trained and deployed.

AI Does Something Subtly Bizarre If You Make Typos While Talking to It

New research suggests that medical AI chatbots are woefully unreliable at understanding how people actually communicate their health problems.

As detailed in yet-to-be-peer-reviewed study presented last month by MIT researchers, an AI chatbot is more likely to advise a patient not to seek medical care if their messages contained typos. The errors AI is susceptible to can be as seemingly inconsequential as an extra space between words, or if the patient used slang or colorful language. And strikingly, women are disproportionately affected by this, being wrongly told not to see a doctor at a higher rate than men.

People Are Rizzing on Tinder Using ChatGPT, Then Showing Up to Dates Completely Tongue-Tied

And with the advent of generative AI, that bleak landscape of modern dating is continuing to evolve in dystopian — and perhaps predictable — ways.

As the Washington Post reports, a 31-year-old named Richard Wilson was startled when his date “had none of the conversational pizzazz she had shown over text.”

Her messages had included “long, multi-paragraph messages” and acknowledgments of “each of his points.” But in person she lacked those conversational chops, and when she mentioned that she used ChatGPT “all the time” for work, the pieces started to fall into place for Wilson.

Real-time trial shows AI could speed cancer care

A new study by researchers at the Icahn School of Medicine at Mount Sinai, Memorial Sloan Kettering Cancer Center, and collaborators, suggests that artificial intelligence (AI) could significantly improve how doctors determine the best treatment for cancer patients—by enhancing how tumor samples are analyzed in the lab.

The findings, published in Nature Medicine, showed that AI can accurately predict genetic mutations from routine pathology slides—potentially reducing the need for rapid genetic testing in certain cases.

The paper is titled “Enhancing Clinical Genomics in Lung Adenocarcinoma with Real-World Deployment of a Fine-Tuned Computational Pathology Foundation Model.”

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