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With the trillions of antibodies the human body can make, finding the antibody with the right combination of potency against a target and ease of manufacturing is, at best, an arduous, time-intensive endeavor for drug developers. AbCellera Biologics Inc. has developed a way to dramatically speed that process.

It is using its proprietary AI system to empower the search. It is mining the diversity of antibodies made by the immune system to find the relatively few that are optimized by nature to be well-suited for drug development. “A human makes trillions of different antibodies, but only a small set binds to the target of interest. Of those, only a few can be developed as drugs,” Carl Hansen, Ph.D., CEO of AbCellera, explained.

Hansen sees AbCellera as a “discovery and innovation shop. We identify the properties of antibodies that make them easy to manufacture and potent.”

There’s been a lot of talk about quantum computers being able to solve far more complex problems than conventional supercomputers. The authors of a new paper say they’re on the pat h to showing an optical computer c an do so, too.

The idea of using light to carry out computing has a long pedigree, and it has gained traction in recent years with the advent of silicon photonics, which makes it possible to build optical circuits using the same underlying technology used for electronics. The technology s hows particular promise for accelerating deep learning, and is being actively pursued by Intel and a number of startups.

Now Chinese researchers have put a photonic chip t o work tackling a fiendishly complex computer science challenge called the s ubset sum problem in a paper in Science Advances. It ha s some potential applications in cryptography and resource allocation, but primarily it’s used as a benchmark to test the limits of computing.

Researchers at the University of Massachusetts and the Air Force Research Laboratory Information Directorate have recently created a 3D computing circuit that could be used to map and implement complex machine learning algorithms, such convolutional neural networks (CNNs). This 3D circuit, presented in a paper published in Nature Electronics, comprises eight layers of memristors; electrical components that regulate the electrical current flowing in a circuit and directly implement neural network weights in hardware.

“Previously, we developed a very reliable memristive device that meets most requirements of in-memory computing for artificial neural networks, integrated the devices into large 2-D arrays and demonstrated a wide variety of machine intelligence applications,” Prof. Qiangfei Xia, one of the researchers who carried out the study, told TechXplore. “In our recent study, we decided to extend it to the third dimension, exploring the benefit of a rich connectivity in a 3D neural .”

Essentially, Prof. Xia and his team were able to experimentally demonstrate a 3D computing circuit with eight memristor layers, which can all be engaged in computing processes. Their circuit differs greatly from other previously developed 3D , such as 3D NAND flash, as these systems are usually comprised of layers with different functions (e.g. a sensor layer, a computing layer, a control layer, etc.) stacked or bonded together.

The news: In a fresh spin on manufactured pop, OpenAI has released a neural network called Jukebox that can generate catchy songs in a variety of different styles, from teenybop and country to hip-hop and heavy metal. It even sings—sort of.

How it works: Give it a genre, an artist, and lyrics, and Jukebox will produce a passable pastiche in the style of well-known performers, such as Katy Perry, Elvis Presley or Nas. You can also give it the first few seconds of a song and it will autocomplete the rest.

TABLE OF CONTENTS —————
:00–15:11 : Introduction
:11–36:12 CHAPTER 1: POSTHUMANISM
a. Neurotechnology b. Neurophilosophy c. Teilhard de Chardin and the Noosphere.

—————————————————————————————–
POSTHUMAN TECHNOLOGY
—————————————————————————————–

:12–54:39 CHAPTER 2 : TELEPATHY/ MIND-READING
a. MRI
b. fMRI
c. EEG
d. Cognitive Liberty e. Dream-recording, Dream-economies f. Social Credit Systems g. Libertism VS Determinism.

:02:07–1:25:48 : CHAPTER 3 : MEMORY/ MIND-AUGMENTING
a. Memory Erasure and Neuroplasticity b. Longterm Potentiation (LTP/LTD)
c. Propanolol d. Optogenetics e. Neuromodulation f. Memory-hacking g. Postmodern Dystopias h. Total Recall, the Matrix, and Eternal Sunshine of the Spotless Mind i. Custom reality and identity.

:25:48–1:45:14 CHAPTER 4 : BCI/ MIND-UPGRADING
a. Bryan Johnson and Kernel b. Mark Zuckerberg and Neuroprosthetics c. Elon Musk, Neural Lace, and Neuralink d. Neurohacking, Neuroadvertizing, Neurodialectics e. Cyborgs, Surrogates, and Telerobotics f. Terminator, Superintelligence, and Merging with AI
g. Digital Analogs, Suffering, and Virtual Drugs h. Neurogaming and “Nervana” (technological-enlightenment)

:45:14 −2:02:57 CHAPTER 5 : CONNECTOME/ MIND-MAPPING

This robot contains the digitized brain of a worm, and without any outside input it just… works! Here’s what this could mean for the future of AI.

This Is How Your Brain Powers Your Thoughts — https://youtu.be/yxUkUaV2VPs

Thumbnail image courtesy of OpenWorm, Wormbase, and Caltech.

Scientists Put a Worm Brain in a Lego Robot Body — And It Worked
http://www.sciencealert.com/scientists-put-worm-brain-in-leg…connectome
“The ultimate goal of the project was to completely replicate C. elegans as a virtual organism. But as an amazing starting point, they managed to simulate its brain, and then they uploaded that into a simple Lego robot.”

These Robots Merge Their Nervous Systems Into a Single Megabot
https://www.seeker.com/tech/robotics/these-robots-merge-thei…le-megabot
“A group of small robots have taken teamwork to the next level, physically connecting and merging their nervous systems to become a single megabot with one “brain.” Researchers describe the robots and their “mergeable nervous system” in a paper published in the latest issue of Nature Communications.”

Will AI Destroy All Humans, or Help Us Build a Better Future?