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Researchers Discover Key to Diseases in Mitochondrial DNA Mutations

New view on mitochondrial DNA could put the brakes on mutations that drive diseases. Scientists perform landmark sequencing of mitochondrial DNA and discover surprising facts.


Summary: New view on mitochondrial DNA could help put the brakes on mutations that drive diseases. [Author: Brady Hartman. This article first appeared on LongevityFacts.]

DNA sequences between mitochondria inside a single cell are vastly different, reported scientists in the Perelman School of Medicine at the University of Pennsylvania. This discovery will help to illuminate the underlying mechanisms of diseases that start with mutations in mitochondrial DNA and provide clues about how patients might respond to specific treatments. The researchers published their findings in the journal Cell Reports this week.

Mutant Mitochondrial DNA

Mitochondria are the tiny organelles that produce energy inside our cells. We have two types of DNA in our bodies, the DNA inside the nucleus of our cells, called nuclear DNA – which stores the vast majority of our genetic code – and a separate DNA inside the mitochondria called mitochondrial DNA (mtDNA).

Inside the ‘star in a jar’ reactor that could lead to limitless energy

A stunning new video has revealed a look inside the Wendelstein 7-X ‘stellarator’ fusion reactor – the largest of its kind in the world.

The video includes a compilation of footage from tests at the massive device, as scientists work to bring humanity closer to achieving ‘limitless’ energy by mimicking the conditions inside the sun.

Bright flashes can be seen erupting inside the reactor, showing the path of super-heated-plasma.

Investigation: Radioactive leaks at Illinois nuclear plants

Radioactive waste continues to pour from Exelon’s Illinois nuclear power plants more than a decade after the discovery of chronic leaks led to national outrage, a $1.2 million government settlement and a company vow to guard against future accidents, an investigation by a government watchdog group found.

Since 2007, there have been at least 35 reported leaks, spills or other accidental releases in Illinois of water contaminated with radioactive tritium, a byproduct of nuclear power production and a carcinogen at high levels, a Better Government Association review of federal and state records shows.

No fines were issued for the accidents, all of which were self-reported by the company.

NASA ‘nuclear engines’ could provide power to the first humans on Mars

NASA is set to begin testing a radical ‘nuclear engine’ that could provide power for astronauts on the Martian surface.

Dubbed the ‘Kilopower’ it would use a uranium rector the size of a toilet roll to create heat.

A high efficiency Stirling engine would then convert this to electricity, in a system that works in a similar way to a car engine.


NASA’s Kilopower engines will use a uranium rector the size of a toilet roll to create heat, then a high efficiency Stirling engine would convert this to electricity.

On the quest for the holy grail for as long as we live

This sort of thing is rapidly going mainstream, and de Grey, if still a fringe thinker, seems increasingly less so. At the very least, medical science has progressed to the point where “negligible senescence” — eternal youth, more or less — is something it might be a good idea to start talking about before it is suddenly upon us without our having thought through the implications. As with most of the other miracle technologies that have turned our lives inside out over the past 100 years — rampant automation, nuclear power, virtual reality, artificial intelligence and so on — this one, as Shukan Gendai points out, has its dark side.


Is death inevitable? True, everyone born before Aug. 4, 1900, has proved mortal (the world’s oldest-known living person, a Japanese woman named Nabi Tajima, was born on that date). But the past is only an imperfect guide to the future, as the effervescent present is ceaselessly teaching us.

Must we die? We ourselves probably must. But our children, our grandchildren — or if not them, theirs — may, conceivably, be the beneficiaries of the greatest revolution ever: the conquest of death.

Dear Future (Trailer)

WATCH THE FIRST EPISODE NOW: http://bit.ly/2yuwDPF

Check out CNET’s channel: http://bit.ly/2gpeXdr

Dear Future is Motherboard and CNET’s new documentary series built on the premise that technology and science are still capable of wowing us. Fusion energy, DIY off-grid energy systems, decentralized mesh networks, the search for life on other planets, and humanoid robots aren’t far-off science fiction, they’re breakthroughs that are happening right now.

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The Race to Create a Star on Earth

If the processes powering the fusion reactor at the Sun’s core could be recreated on Earth, it would be one of the most important events in the history of our species. Nuclear fusion power plants could end our dependency on fossil fuels and provide a virtually limitless, highly efficient source of clean energy.

We went to two of the world’s leading nuclear fusion research centers—Sandia National Labs in New Mexico and General Fusion outside Vancouver—to see how close we are to bringing the power of the stars down to Earth.

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