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Category: neuroscience – Page 90

Black holes have long fascinated scientists, known for their ability to trap anything that crosses their event horizon. But what if there were a counterpart to black holes? Enter the white hole—a theoretical singularity where nothing can enter, but energy and matter are expelled with immense force.

First proposed in the 1970s, white holes are essentially black holes in reverse. They rely on the same equations of general relativity but with time flowing in the opposite direction. While a black hole pulls matter in and lets nothing escape, a white hole would repel matter, releasing high-energy radiation and light.

Despite their intriguing properties, white holes face significant scientific challenges. The laws of thermodynamics, particularly entropy, make it improbable for matter to move backward in time, as white holes would require. Additionally, introducing a singularity into the Universe without a preceding collapse defies current understanding of cosmic evolution.

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Summary: New research suggests that certain nutrients may lower iron buildup in the brain, a factor linked to cognitive decline in aging. Excess non-heme iron, which accumulates over time, contributes to oxidative stress and can impair memory and executive function.

Over three years, participants with higher intake of antioxidants, vitamins, and iron-chelating nutrients showed less brain iron accumulation and better cognitive performance. These findings highlight the potential of diets like the Mediterranean or DASH to support brain health and combat age-related cognitive decline.

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Dopamine is a powerful signal in the brain, influencing our moods, motivations, movements, and more. The neurotransmitter is crucial for reward-based learning, a function that may be disrupted in a number of psychiatric conditions, from mood disorders to addiction.

Now, researchers led by MIT Institute Professor Ann Graybiel have found surprising patterns of dopamine signaling that suggest neuroscientists may need to refine their model of how occurs in the brain. The team’s findings were published recently in the journal Nature Communications.

Dopamine plays a critical role in teaching people and other animals about the cues and behaviors that portend both positive and negative outcomes; the classic example of this type of learning is the dog that Ivan Pavlov trained to anticipate food at the sound of bell.

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In a recent study published in the journal Nature Aging, researchers identified plasma proteomic biomarkers and dynamic changes associated with brain aging, leveraging a multimodal approach combining brain age gap (BAG) and proteome-wide association analysis.

Background

The global aging population is expected to exceed 1.5 billion individuals aged 65 and above by 2050, highlighting the urgent need to address aging-associated challenges.

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The shift from an awake state to unconsciousness is a phenomenon that has long captured the interest of scientists and philosophers alike, but how it happens has remained a mystery—until now. Through studies on rats, a team of researchers at Penn State has pinpointed the exact moment of loss of consciousness due to anesthesia, mapping what happens in different brain regions during that moment.

The study has implications for humans as well as for other types of loss of , such as sleep, the researchers said. They published their results in Advanced Science.

“People in the neuroscience field generally understand what happens to a patient who is going under anesthesia at a ,” said corresponding author Nanyin Zhang, the Dorothy Foehr Huck and J. Lloyd Huck Chair in Brain Imaging and professor of biomedical engineering at Penn State.

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Summary: The dural sinuses and skull bone marrow serve as key communication hubs between the brain’s central immune system and the body’s peripheral immune system. These regions may act as “traffic lights,” allowing immune signals to flow between the brain and body, challenging the traditional view of the blood-brain barrier as an absolute divide.

Researchers found inflammatory activity in these areas correlates with inflammation in both the brain and body, offering new insights into conditions like depression. This discovery could pave the way for innovative treatments targeting these hubs to address immune-related conditions more precisely.

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