“The neuroscience is pretty uncomfortable. People in positions of power show reduced activity in mirror neuron systems, the circuitry responsible for empathy and perspective-taking.” –Shonna Waters, PhD.
Category: neuroscience – Page 87
These Physicists Say They Found The Origin Of Reality
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One of the most perplexing questions in the foundations of physics is how our shared sense of reality emerges out of quantum mechanics. This is because in quantum mechanics, it seems, different observers can arrive at different conclusions about what is real and what not. A group of physicists now used an approach called “Quantum Darwinism” to solve this tricky problem. At least they say they solved it. I am not so sure. Let’s have a look.
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/ @sabinehossenfelder 📚 Buy my book ➜ https://amzn.to/3HSAWJW #science #sciencenews #quantum #physics This video discusses the concept of “reality” in quantum physics, touching on how different observers can reach different conclusions. It features a presentation of a scientific paper on the “Metrological approach to the emergence of classical objectivity,” suggesting a potential solution to a long-standing problem in quantum mechanics. We explore how the “observer effect” and individual “consciousness” play a crucial role in shaping our understanding of “reality does not exist” within the realm of “quantum physics explained.” This deep dive connects the fundamental principles of “quantum mechanics” with profound questions in “philosophy.”
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💌 Support me on Donorbox ➜ https://donorbox.org/swtg.
👉 Transcript with links to references on Patreon ➜ / sabine.
📝 Transcripts and written news on Substack ➜ https://sciencewtg.substack.com/
📩 Free weekly science newsletter ➜ https://sabinehossenfelder.com/newsle…
👂 Audio only podcast ➜ https://open.spotify.com/show/0MkNfXl…
🔗 Join this channel to get access to perks ➜
/ @sabinehossenfelder.
📚 Buy my book ➜ https://amzn.to/3HSAWJW
#science #sciencenews #quantum #physics.
This video discusses the concept of \.
Beyond the bleed: complications after aneurysmal subarachnoid hemorrhage. Pathophysiology, clinical implications, and management strategies: a review
Aneurysmal subarachnoid hemorrhage is a critical condition with high case-fatality and lasting impacts on survivors. Acute events that are the direct result of aneurysm rupture, such as acute ischemia, elevated intracranial pressure, cerebral edema, seizures, and hydrocephalus, lead to early brain injury. A delayed cascade of processes, including a prominent systemic inflammatory response, may lead to secondary brain injury and delayed cerebral ischemia, which often further impairs recovery. Systemic complications, including cardiac and pulmonary dysfunction, fever, and electrolyte imbalances, arise in the interplay between early and secondary brain injury and challenge the clinical course.
Autism’s Link to Parkinson’s Risk May Finally Be Explained
People with autism may be up to six times more likely to develop Parkinson’s disease in later life. New research offers a potential explanation based on the role of transporter molecules that recycle unused dopamine in the brain.
Dopamine is a neurotransmitter crucial for managing movement and executive functions, and for reinforcing behavior. It’s well known that Parkinson’s is characterized by a drop in dopamine levels, while disruptions in the transport of the chemical have also been linked to autism.
With that context, researchers led by a team from the University of Missouri in the US took a novel approach using a technology known as a DaT SPECT scan, which is typically used to diagnose Parkinson’s in much older people.
Type-specific transposon demethylation and TAD remodeling in aging mouse brain
Now online! A multi-omic single-cell atlas of the aging mouse brain reveals cell-type-specific transposon methylation changes, strengthening of 3D genome boundaries, and regionally heterogeneous aging signatures. These findings offer a resource to understand the molecular mechanisms of brain aging and guide future research on neurodegeneration.
Scientists Teach A Dish Of Human Neurons To Play DOOM
Who cares about running DOOM on a pregnancy test?
Enhancing gut-brain communication reversed cognitive decline, improved memory formation in aging mice
The sight of a delectable plate of lasagna or the aroma of a holiday ham are sure to get hungry bellies rumbling in anticipation of a feast to come. But although we’ve all experienced the sensation of “eating” with our eyes and noses before food meets mouth, much less is known about the information superhighway, known as the vagus nerve, that sends signals in the opposite direction — from your gut straight to your brain.
These signals relay more than just what you’ve eaten and when you are full. A new study in mice from researchers at Stanford Medicine and the Palo Alto, California-based Arc Institute has identified a critical link between the bacteria that live in your gut and the cognitive decline that often occurs with aging.
“Although memory loss is common with age, it affects people differently and at different ages,” said Christoph Thaiss, PhD, assistant professor of pathology. “We wanted to understand why some very old people remain cognitively sharp while other people see significant declines beginning in their 50s or 60s. What we learned is that the timeline of memory decline is not hardwired; it’s actively modulated in the body, and the gastrointestinal tract is a critical regulator of this process.”
Aging causes changes in gut bacteria in mice, which hampers communication between the intestines and the brain. Restoring this connection helped old mice form memories as well as young animals.
Oligodendrocyte molecular perturbations associated with tau in Alzheimer’s
The findings suggest that in AD, part of what happens in the brain may involve changes in DNA tagging that affect the function of oligodendrocytes, particularly in relation to the buildup of the toxic protein tau.
Oligodendrocytes are the brain cells that make myelin, the insulation that helps nerve cells communicate. Scientists have theorized that disrupting neuron communication contributes to symptoms for people with AD. Researchers in this study found that nearly all significant methylation changes — small chemical tags added to DNA that help control when genes are turned on or off — were linked to the tau protein. This supports the idea that this protein plays a key role in brain cell changes tied to AD.
“Our team has previously shown that oligodendrocytes are affected in Alzheimer’s and another tau-related disease, progressive supranuclear palsy (PSP),” says the author. “These new results further highlight that problems in oligodendrocytes and myelin are central to AD. They also point to specific molecular pathways, particularly epigenetic changes, that could be targeted in future therapies.”
The study results identified new genes that may play a role in AD, including one called LDB3, and confirmed many findings across multiple independent datasets, showing its reliability. The identification of specific genes provides potential targets for future research — for example, scientists might investigate whether interventions that reverse methylation or support oligodendrocyte health can slow or modify disease progression for patients with AD. ScienceMission sciencenewshighlights.
In a study published in Nature Communications, the researchers have identified specific DNA-level changes in the brains of people with Alzheimer’s disease (AD). Using advanced biological analysis, the team mapped alterations in the brain’s regulatory landscape that may help explain why Alzheimer’s presents and progresses differently from person to person. The findings could also open new avenues for understanding other neurodegenerative diseases.
Alzheimer’s disease is the most common cause of dementia. Biologically, the disease begins with the formation of protein deposits, known as amyloid plaques, and neurofibrillary tangles in the brain. This causes brain cells to die over time and the brain to shrink. About 6.9 million people in the U.S. age 65 and older live with Alzheimer’s disease. There is no cure, and in advanced stages, complications can result in a significant decline in quality of life and death.