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Social behavior (SB) is a fundamental hallmark of human interaction. Repeated administration of low doses of the 5-HT2A agonist lysergic acid diethylamide (LSD) in mice enhances SB by potentiating 5-HT2A and AMPA receptor neurotransmission in the mPFC via an increasing phosphorylation of the mTORC1, a protein involved in the modulation of SB. Moreover, the inactivation of mPFC glutamate neurotransmission impairs SB and nullifies the prosocial effects of LSD. Finally, LSD requires the integrity of mTORC1 in excitatory glutamatergic, but not in inhibitory neurons, to produce prosocial effects. This study unveils a mechanism contributing to the role of 5-HT2A agonism in the modulation of SB.

All study data are included in the article and supporting information.

Well, maybe they would be good memories. 😃


Quantum computers, according to experts, will one day be capable of performing incredible calculations and nearly unfathomable feats of logic. In the near future, we know they’ll help us discover new drugs to fight disease and new materials to build with. But the far future potential for these enigmatic machines is as vast as the universe itself.

The realm of classic science fiction is littered with ideas that today’s experts believe lie within the realm of reality – if not today’s reality, then perhaps tomorrow’s quantum computer-laden one. One of those ideas comes straight out of a Paul Verhoeven film from over thirty years ago: Total Recall.

I think we may need to be more careful about brain implants in the future. 😃


Cutting down on the number of invasive surgeries associated with implants is one thing, but the wireless implant also stands to improve the quality of animal research. Without wireless controls or charging, animals needed to be wired up to power sources or other electronics with invasive, restrictive tethers. Doing away with those allows the animals to behave how they normally would have.

In the case of this particular test, KAIST scientists used the implant to block cocaine-associated behaviors in rats who they had just injected with the drug. But they suspect the underlying tech could be used in all sorts of implants and medical devices.

“We believe that the same basic technology can be applied to various types of implants, including deep brain stimulators, and cardiac and gastric pacemakers,” Jeong said in the release, “to reduce the burden on patients for long-term use within the body.”

A tiny implant offers a new weight loss option, and a gastric bypass alternative, for people suffering from obesity.

The device uses light to stimulate the nerve responsible for regulating food intake. A tiny glow from the implant and users don’t feel as hungry — instead, they feel full.

Researchers at Texas A&M say that this dime-sized device could provide a far less invasive surgical option than the so-called stomach stapling surgery — which is currently a last resort surgery for obese patients. This could be a viable option for a gastric bypass alternative.

HOUSTON — (Jan. 252021) — Wireless communication directly between brains is one step closer to reality thanks to $8 million in Department of Defense follow-up funding for Rice University neuroengineers.

The Defense Advanced Research Projects Agency (DARPA), which funded the team’s proof-of-principle research toward a wireless brain link in 2018, has asked for a preclinical demonstration of the technology that could set the stage for human tests as early as 2022.

“We started this in a very exploratory phase,” said Rice’s Jacob Robinson, lead investigator on the MOANA Project, which ultimately hopes to create a dual-function, wireless headset capable of both “reading” and “writing” brain activity to help restore lost sensory function, all without the need for surgery.

Researchers at Tokyo Medical and Dental University (TMDU) in Japan show that melatonin and its metabolites promote the formation of long-term memories in mice and protect against cognitive decline.

Researchers at Tokyo Medical and Dental University (TMDU) showed that melatonin’s metabolite AMK can enhance the formation of long-term memories in mice. Memory of objects were tested after treatment with melatonin or two of its metabolites. Older mice that normally performed poorly on the memory task showed improvements as dosage increased. The metabolite AMK was found to be the most important as melatonin failed to improve memory if it was blocked from metabolizing into AMK.

Walk down the supplement aisle in your local drugstore and you’ll find fish oil, ginkgo, vitamin E, and ginseng, all touted as memory boosters that can help you avoid cognitive decline. You’ll also find melatonin, which is sold primarily in the United States as a sleep supplement. It now looks like melatonin marketers might have to do a rethink. In a new study, researchers led by Atsuhiko Hattori at Tokyo Medical and Dental University (TMDU) in Japan have shown that melatonin and two of its metabolites help memories stick around in the brain and can shield mice, and potentially people, from cognitive decline.

Like periods in women, after a while our brains waves synchronise with the people we share our communications (family, friends, co-workers, church members, social media, etc.) so, it is good to know what are those and how they affect others and you.


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