Archive for the ‘neuroscience’ category: Page 627
Dec 14, 2019
Micro implants could restore walking in spinal injury patients
Posted by Genevieve Klien in categories: biotech/medical, health, neuroscience
People tend to think the brain does all the thinking, but the spinal cord has built-in intelligence, Mushahwar says. A complex chain of motor and sensory networks regulate everything from breathing to bowels, while the brain stem’s contribution is basically “go!” and “faster!” Your spinal cord isn’t just moving muscles, it’s giving you your natural gait.
Being able to control standing and walking would improve bone health, improve bowel and bladder function, and reduce pressure ulcers, the researchers say. For those with less severe spinal injuries, an implant could be therapeutic, removing the need for months of gruelling physical therapy regimes that have limited success, they add.
The team say they are now going to focus on refining the hardware further by miniaturising an implantable stimulator and getting approval from Health Canada and the FDA for human trials. The first generation of the implants will require a patient to control walking and movement through physical means, but longer term, the implants could potentially include a direct connection to the brain, they say.
Dec 14, 2019
Human Brains Have Tiny Bits of Magnetic Material
Posted by Genevieve Klien in categories: materials, neuroscience
Here’s the first map of the magnetic mineral magnetite in the human brain. Turns out that our brain stem may be full of it.
Dec 13, 2019
New methods could help researchers watch neurons compute
Posted by Saúl Morales Rodriguéz in categories: computing, neuroscience
Since the 1950s at least, researchers have speculated that the brain is a kind of computer in which neurons make up complex circuits that perform untold numbers of calculations every second. Decades later, neuroscientists know that these brain circuits exist, yet technical limitations have kept most details of their computations out of reach.
Now, neuroscientists reported December 12 in Cell, they may finally be able to reveal what circuits deep in the brain are up to, thanks in large part to a molecule that lights up brighter than ever before in response to subtle electrical changes that neurons use to perform their compuations.
Currently, one of the best ways to track neurons’ electrical activity is with molecules that light up in the presence of calcium ions, a proxy for a neuron spike, the moment when one neuron passes an electrical signal to another. But calcium flows too slowly to catch all the details of a neuron spike, and it doesn’t respond at all to the subtle electrical changes that lead up to a spike. (One alternative is to implant electrodes, but those implants ultimately damage neurons, and it isn’t practical to place electrodes in more than a handful of neurons at once in living animals.)
Dec 13, 2019
Experts review evidence yoga is good for the brain
Posted by Paul Battista in categories: biotech/medical, health, neuroscience
Scientists have known for decades that aerobic exercise strengthens the brain and contributes to the growth of new neurons, but few studies have examined how yoga affects the brain. A review of the science finds evidence that yoga enhances many of the same brain structures and functions that benefit from aerobic exercise.
The review, published in the journal Brain Plasticity, focused on 11 studies of the relationship between yoga practice and brain health. Five of the studies engaged individuals with no background in yoga practice in one or more yoga sessions per week over a period of 10–24 weeks, comparing brain health at the beginning and end of the intervention. The other studies measured brain differences between individuals who regularly practice yoga and those who don’t.
Each of the studies used brain-imaging techniques such as MRI, functional MRI or single-photon emission computerized tomography. All involved Hatha yoga, which includes body movements, meditation and breathing exercises.
Dec 12, 2019
By turning stem cells into brain cells, Aspen Neuroscience hopes to rewind the progress of Parkinson’s disease
Posted by Paul Battista in categories: biotech/medical, genetics, neuroscience
The idea of a cell therapy for Parkinson’s disease starts out simple: Symptoms of the progressive disease are largely driven by the deaths of dopamine-producing neurons found deep within the brain. With lower levels of the neurotransmitter come the characteristic tremors, rigidity and slow movements.
By replacing those lost nerve cells with new dopamine producers, researchers hope to renew the brain’s connection to the body’s muscles and improve a person’s overall motor function.
But in the brain, everything becomes more complicated. On top of the risk of immune system rejection that comes with any kind of living tissue transplant, it’s important to make sure the implanted cells function correctly and do not pick up any dangerous genetic mutations as they grow.
Dec 12, 2019
Scientists Reverse Cognitive Deficits of Down Syndrome in Mice
Posted by Shane Hinshaw in category: neuroscience
Dec 12, 2019
Dementia study reveals how proteins interact to stop brain signals
Posted by Genevieve Klien in categories: biotech/medical, neuroscience
Fresh insights into damaging proteins that build up in the brains of people with Alzheimer’s disease could aid the quest for treatments.
A study in mice reveals how the two proteins work together to disrupt communication between brain cells.
Scientists observed how proteins—called amyloid beta and tau—team up to hamper key genes responsible for brain messaging. By changing how genes are expressed in the brain, the proteins can affect its normal function.
Dec 11, 2019
Doctors successfully transplanted a heart after it stopped beating in a first-its-kind procedure in the US
Posted by Shailesh Prasad in categories: biotech/medical, neuroscience
The procedure, donation after circulatory death or DCD, involves taking organs from a donor whose heart has stopped beating after being taken off of life support after a fatal injury or illness when there is no potential for recovery.
Conventional organ donations occur after brain death, which means that while all brain functions have stopped and the person is legally and clinically dead, machines can continue to keep oxygen and blood flowing throughout the body, preserving the healthy organs for donation.
After a circulatory death, however, organs are deprived of oxygen as the circulatory system shuts down, potentially damaging the donor organs and making it difficult to use them for transplant.