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Rare Brain-eating amoeba puts Missouri resident; 1st in 35 years

Although rare, people become infected by Naegleria fowleri when water containing the amoeba enters the body through the nose. It then travels to the brain, where it destroys brain tissue. This infection cannot spread from one person to another, and it cannot be contracted by swallowing contaminated water.

“These situations are extremely rare in the United States and in Missouri specifically, but it’s important for people to know that the infection is a possibility so they can seek medical care in a timely manner if related symptoms present,” Dr. George Turabelidze, Missouri’s state epidemiologist, said in a statement.

Symptoms can include severe headaches, fever, nausea, vomiting, stiff neck, seizures, altered mental state and hallucinations. Anyone who experiences these symptoms after swimming in a warm body of water should contact their health care provider immediately.

What is a Thought? How the Brain Creates New Ideas | Henning Beck | TEDxHHL

How does the human brain work and how is it different from computers? If you think this is too complex to explain in a few minutes, you will be surprised. In this energetic and insightful talk, neuro-scientist Dr. Henning Beck gives insights into thought processes and tells you how you can create new ideas.

Dr. Henning Beck, neuroscientist and author, supports businesses to use brain-based approaches in order to develop innovative and efficient workflows. He studied biochemistry in Tübingen from 2003 to 2008. After his diploma thesis, he started his research at the Hertie Institute for Clinical Brain Research and intensified his work at the Institute of Physiological Chemistry at the University of Ulm. Supported by a PhD scholarship granted by the Hertie Foundation he did his doctorate at the Graduate School of Cellular & Molecular Neuroscience in Tübingen. He expanded his scientific expertise by an International Diploma in Project Management at the University of California, Berkeley in 2013. Until 2014, he worked for start-ups in the San Francisco Bay Area to develop creative workspace designs and advanced communication styles based on neuroscientific principles.

This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

Imagining the Future: The Transformation of Humanity | Peter Diamandis | TEDxLA

In this landmark talk, Peter Diamandis shares how we are rapidly heading towards a human-scale transformation, the next evolutionary step into what he calls a “Meta-Intelligence,” a future in which we are all highly connected — brain to brain via the cloud — sharing thoughts, knowledge and actions.
He highlights the 4 driving forces as well as the 4 steps that is transforming humanity.

In 2014 Fortune Magazine named Peter Diamandis as one of the World’s 50 Greatest Leaders.

Diamandis He is the Founder & Executive Chairman of the XPRIZE Foundation which leads the world in designing and operating large-scale incentive competitions. He is also the Co-Founder & Exec Chairman of Singularity University, a graduate-level Silicon Valley institution that counsels the world’s leaders on exponentially growing technologies.

As an entrepreneur, Diamandis has started 17 companies. He is the Co-Founder and Vice-Chairman of Human Longevity Inc. (HLI), a genomics and cell therapy-based company focused on extending the healthy human lifespan, and Co-Founder and Co-Chairman of Planetary Resources, a company designing spacecraft to enable the detection and prospecting of asteroid for fuels and precious materials.

Peter Diamandis earned degrees in Molecular Genetics and Aerospace Engineering from the MIT, and holds an M.D. from Harvard Medical School.

This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

Millennial mental health toll spikes during COVID

There has been a spike in severe psychological distress in young Australian adults under 35, according to new analysis from The Australian National University (ANU).

The study—which tracked 3,155 Australians—is the first-of-its-kind to compare mental health data before and during the COVID-19 pandemic.

“Young Australians aged 18 to 24 and those aged 25 to 34 are significantly worse off in terms of mental health than those who are older,” Associate Professor Ben Edwards, from the ANU Centre for Social Research and Methods, said.

New study shows staggering effect of coronavirus pandemic on America’s mental health

When the novel coronavirus roared into the U.S., mental health took a back seat to physical health. The number one priority was making sure hospitals wouldn’t be overwhelmed and that as many lives as possible could be saved.

Schools closed, remote work became the norm, restaurants shuttered and getting together with friends was no longer possible. The news cycle spun with story after story highlighting the ever-increasing number of cases and deaths, while unemployment soared to levels not seen since the Great Depression.

Any one of these shifts could be expected to cause an increase in issues. Put together, they created a a perfect storm for a crisis.

Coronavirus lockdown made many of us anxious. But for some people, returning to ‘normal’ might be scarier

Many Australians have welcomed the gradual easing of coronavirus restrictions. We can now catch up with friends and family in small numbers, and get out and about a little more than we’ve been able to for a couple of months.

All being well, restrictions will continue to be lifted in the weeks and months to come, allowing us slowly to return to some kind of “normal”.

This is good news for the economy and employment, and will hopefully help ease the high levels of distress and mental health problems our community has been experiencing during the pandemic.

Mindfulness meditation reduces pain by separating it from the self

For centuries, people have been using mindfulness meditation to try to relieve their pain, but neuroscientists have only recently been able to test if and how this actually works. In the latest of these efforts, researchers at University of California San Diego School of Medicine measured the effects of mindfulness on pain perception and brain activity.

The study, published July 7, 2022 in Pain, showed that interrupted the communication between brain areas involved in sensation and those that produce the sense of self. In the proposed mechanism, still move from the body to the brain, but the individual does not feel as much ownership over those pain sensations, so their pain and suffering are reduced.

“One of the central tenets of mindfulness is the principle that you are not your experiences,” said senior author Fadel Zeidan, Ph.D., associate professor of anesthesiology at UC San Diego School of Medicine. “You train yourself to experience thoughts and sensations without attaching your ego or sense of self to them, and we’re now finally seeing how this plays out in the brain during the experience of acute pain.”

Scientists discover the function and connections of three cell types in the brain

How the brain functions is still a black box: scientists aren’t even sure how many kinds of nerve cells exist in the brain. To know how the brain works, they need to know not only what types of nerve cells exist, but also how they work together. Researchers at the Salk Institute have gotten one step closer to unlocking this black box.

Using cutting-edge visualization and genetic techniques, the team uncovered a new subtype of nerve cell, or neuron, in the visual cortex. The group also detailed how the new cell and two similar neurons process images and connect to other parts of the . Learning how the brain analyzes visual information at such a detailed level may one day help doctors understand elements of disorders like schizophrenia and autism.

“Understanding these contributes another piece to the puzzle uncovering neural circuits in the brain, circuits that will ultimately have implications for neurological disorders,” says Edward Callaway, Salk professor and senior author of the paper published December 6 in the journal Neuron.

Alzheimer’s disease biomarkers can predict postoperative delirium

Clinical studies have demonstrated a strong association between Alzheimer’s disease (AD) and delirium. A change to the Tau protein, which can lead to the formation of tangles in brain, is one of the hallmarks of AD pathology, and Tau phosphorylation at threonine 217 (Tau-PT217) and threonine 181 (Tau-PT181) are new plasma biomarkers that can detect early-stage AD. A clinical study led by investigators at Massachusetts General Hospital (MGH) has shown that plasma Tau-PT217 and Tau-PT181 are associated with incidence and severity of postoperative delirium. The findings are published in Annals of Surgery.

Early studies from the same research group at MGH have shown that the ratio of beta amyloid (which causes AD’s signature plaques) to Tau in cerebrospinal fluid is associated with . Recent studies in other labs have reported that plasma Tau-PT181 concentration distinguishes AD dementia from other neurological disorders. Plasma levels of Tau-PT217 are associated with the changes in levels of Tau-PT217 and AD development.

In this current study, the team at MGH developed a novel method to measure Tau-PT217 and Tau-PT181 concentrations in plasma of patients, called nanoneedle technology, in collaboration with NanoMosaic (Woburn, MA). “The nanoneedle technology is ultrasensitive, requires a small volume, and can measure low concentrations of molecules, including Tau-PT217 and Tau-PT181,” says lead author Feng Liang, MD, Ph.D., in the Department of Anesthesia, Critical Care and Pain Medicine at MGH. “More than 20,000 nanoneedles are integrated on a silicon substrate assigned to detect one analyte. Each nanoneedle is a single molecule biosensor functionalized with antibodies,” says Liang.