A future with human brain-chip interfaces is not very far as Samsung has a published a Perspective paper titled “Neuromorphic electronics based on copying and pasting the brain”, which talks about a new way to copy th…
Category: neuroscience – Page 598
An inexpensive anti-seizure medication markedly improves learning and memory and other cognitive functions in Alzheimer’s patients who have epileptic activity in their brains, according to a study published in the Sept. 27th issue of JAMA Neurology.
“This is a drug that’s used for epilepsy,” says Keith Vossel, MD, MSc, director of the Mary S. Easton Center for Alzheimer’s Disease Research at UCLA, and the principal investigator on the clinical trial. “We used it in this study for Alzheimer’s patients who had evidence of silent epileptic activity, which is seizure-like brain activity without the associated physical convulsions.”
Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Early symptoms include short-term memory loss, decline in problem solving, word-finding difficulties, and trouble with spatial navigation. Among Alzheimer’s patients, an estimated 10–22% develop seizures, while an additional 22–54% exhibit silent epileptic activity.
A large, UK-based study of genetics and autism spectrum disorder (ASD) has been suspended, following criticism that it failed to properly consult the autism community about the goals of the research. Concerns about the study include fears that its data could potentially be misused by other researchers seeking to ‘cure’ or eradicate ASD.
Study aimed at collecting DNA from 10,000 people with autism and their families has drawn criticism for failing to consult the autism community.
Dr. Jennifer Garrison, PhD (http://garrisonlab.com/) is Assistant Professor, Buck Institute for Research on Aging, Founder & Faculty Director, Global Consortium for Reproductive Longevity & Equality (https://www.buckinstitute.org/gcrle/), Assistant Professor in Residence, Cellular and Molecular Pharmacology, UCSF and Adjunct Assistant Professor of Gerontology, USC Leonard Davis School of Gerontology.
Dr. Garrison’s lab is interested in understanding how neuropeptides (a large class of signaling molecules which are secreted from neurons and transmit messages within the brain and across the nervous system) regulate changes in normal and aging animals as well in understanding how they control behavior at both the cell biological and neural circuit level.
Dr. Garrison received her PhD from the University of California San Francisco in Chemistry and Chemical Biology in the laboratory of Dr. Jack Taunton, where she discovered the molecular target of a natural product and elucidated a novel mechanism by which small molecules can regulate protein biogenesis. As a postdoctoral fellow in Dr. Cori Bargmann’s lab at the Rockefeller University, she showed that the nematode C. elegans produces a neuropeptide that is an evolutionary precursor of the mammalian peptides vasopressin and oxytocin, and mapped a neural circuit by which this molecule, nematocin, modulates mating behavior.
Dr. Garrison was named an Alfred P. Sloan Research Fellow and received a Glenn Foundation Award for Research in Biological Mechanisms of Aging in 2,014 and a Next Generation Leader at the Allen Institute for Brain Science in 2015. Her work is funded by the NIH National Institute of General Medical Sciences, the Glenn Foundation for Medical Research, the Alfred P. Sloan Foundation, and the Larry L. Hillblom Foundation.
“Our mathematical equation lets us predict which individuals will have both more happiness and more brain activity for intrinsic compared to extrinsic rewards. The same approach can be used in principle to measure what people actually prefer without asking them explicitly, but simply by measuring their mood.”
Summary: A new mathematical equation predicts which individuals will have more happiness and increased brain activity for intrinsic rather than extrinsic rewards. The approach can be used to predict personal preferences based on mood and without asking the individual.
Source: UCL
A new study led by researchers at the Wellcome Centre for Human Neuroimaging shows that using mathematical equations with continuous mood sampling may be better at assessing what people prefer over asking them directly.
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Studying transitions in and out of the altered state of consciousness caused by intravenous (IV) N, N-Dimethyltryptamine (DMT — a fast-acting tryptamine psychedelic) offers a safe and powerful means of advancing knowledge on the neurobiology of conscious states. Here we sought to investigate the effects of IV DMT on the power spectrum and signal diversity of human brain activity (6 female, 7 male) recorded via multivariate EEG, and plot relationships between subjective experience, brain activity and drug plasma concentrations across time. Compared with placebo, DMT markedly reduced oscillatory power in the alpha and beta bands and robustly increased spontaneous signal diversity. Time-referenced and neurophenomenological analyses revealed close relationships between changes in various aspects of subjective experience and changes in brain activity.
A weird and brilliantly effective optical illusion that has gone viral on the internet tricks your brain into seeing a color image … but if you look closely you will notice that the photo you are looking at is only black and white.
The viral image was created by artist and developer Øyvind Kolås who carefully overlaid red, orange, yellow, blue, and green grid lines over black and white images.
“An over-saturated coloured grid overlaid on a grayscale image causes the grayscale cells to be perceived as having colour,” Kolås explains on his Patreon page.
The key is an innovation that’s being called ‘light beads microscopy’. It improves on current two-photon microscopy, using lasers to trigger introduced fluorescence in living cells. As the cells are lit up, scientists can see how they’re moving and interacting.
With light beads microscopy, scientists can get the speed, scale, and resolution required to map a mouse brain in detail as its neural activity changes. The near-simultaneous tracking can last for as long as the light beads are able to stay illuminated.
Discoveries by Deisseroth and his two co-recipients regarding microbial light-activated molecules led to his development of a way to manipulate selected neurons in living animals to observe changes in their behavior.