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University of Iowa researchers have confirmed in a new study that a specific region in the brain is critical to governing the mind’s communication with the body’s motor control system. The findings could yield advances in treatment for Parkinson’s disease, as declining motor coordination is a central symptom of the disorder.

In experiments with humans, the researchers pinpointed the as the region in the that communicates with the motor system to help the body stop an action. This communication is vital because it helps humans avoid surprises and react to potentially dangerous or unforeseen circumstances.

The subthalamic nucleus is a tiny grouping of cells that is part of the , which is a key circuit in controlling movement. The basal ganglia takes initial motor commands generated in the brain and either amplify or halt specific parts of those commands as they pass from the central nervous system to the spinal cord.

Figuring out what’s going on in the brain is generally considered to be somewhere between extremely difficult and impossible. One major challenge is that the best ways to do so are room-sized machines relegated to hospitals — but brain.space is hoping that its portable, powerful and, most importantly, user-friendly EEG helmet could power new applications and treatments at home and, as a sort of cork pop for its debut, in space.

Electroencephalography, or EEG, is an established method for monitoring certain signals the brain produces. An EEG can indicate which areas of the cortex are active, whether the user is concentrating, agitated, and so on. It’s not nearly as precise as an MRI, but all you need for an EEG is a set of electrical contacts on the scalp, while an MRI machine is huge, loud and incredibly expensive.

There’s been precious little advancement in EEG tech, though, and it’s often done more or less the same way it was done decades ago. Recently, that’s begun to change with devices like Cognixion’s, which uses re-engineered EEG to interpret specific signals with the goal of allowing people with motor impairments to communicate.

Credit: Neuroimaging and Informatics Institute:

Dopaminergic Transmission.

Handbook of Basal Ganglia Structure and Function, Second Edition: https://www.sciencedirect.com/topics/neuroscience/dopaminergic-transmission.

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Antoine Galand, Director of Technology, GraphWear

Nanotechnology was once the stuff of science fiction, but today the concept of creating devices and machines that are several thousand times smaller than the width of a human hair is a well-established fact. The rise of nanotechnology has already transformed industries ranging from consumer electronics to textile manufacturing and cosmetics by unlocking new materials and processes at the nanoscale. The device you’re reading this on, for example, is only possible because of techniques adopted in the semiconductor industry that enable us to pattern silicon and metals to create the microscopic circuits and switches that are at the heart of modern computers.

One of the most promising applications of our newfound ability to manipulate individual atoms and molecules is in healthcare, where the ability of doctors to treat disease has been hamstrung by relatively blunt “macro” solutions. The human body is a remarkably complex system where, fundamentally, nanoscale processes occurring inside cells are what determine whether we are sick or healthy. If we’re ever going to cure diseases like diabetes, cancer or Alzheimer’s, we need technologies that work at their scale. Although medical nanotechnologies are relatively new, they’re already impacting the way we diagnose, treat and prevent a broad range of diseases.

Summary: Researchers reveal how neurons set up and sustain the vital infrastructure that allows for seamless neurotransmission.

Source: picower institute for learning and memory.

The nervous system works because neurons communicate across connections called synapses. They “talk” when calcium ions flow through channels into “active zones” that are loaded with vesicles carrying molecular messages.

Neuroscientist and physician Matthew Schrag found suspect images in dozens of papers involving Alzheimer’s disease, including Western blots (projected in green) measuring a protein linked to cognitive decline in rats.

The Neuro-Network.

𝐁𝐋𝐎𝐓𝐒 𝐎𝐍 𝐀 𝐅𝐈𝐄𝐋𝐃?

𝘼 𝙣𝙚𝙪𝙧𝙤𝙨𝙘𝙞𝙚𝙣𝙘𝙚 𝙞𝙢𝙖𝙜𝙚 𝙨𝙡𝙚𝙪𝙩𝙝 𝙛𝙞𝙣𝙙𝙨 𝙨𝙞𝙜𝙣𝙨 𝙤𝙛 𝙛𝙖𝙗𝙧𝙞𝙘𝙖𝙩𝙞𝙤𝙣 𝙞𝙣 𝙨𝙘𝙤𝙧𝙚𝙨 𝙤𝙛 𝘼𝙡𝙯𝙝𝙚𝙞𝙢𝙚𝙧’𝙨 𝙖𝙧𝙩𝙞𝙘𝙡𝙚𝙨, 𝙩𝙝𝙧𝙚𝙖𝙩𝙚𝙣𝙞𝙣𝙜 𝙖 𝙧𝙚𝙞𝙜𝙣𝙞𝙣𝙜 𝙩𝙝𝙚𝙤𝙧𝙮