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Category: neuroscience – Page 511

Rats love to dance đŸ•ș:3

The team had two alternate hypotheses: The first was that the optimal music tempo for beat synchronicity would be determined by the time constant of the body. This is different between species and much faster for compared to humans (think of how quickly a rat can scuttle). The second was that the optimal tempo would instead be determined by the time constant of the brain, which is surprisingly similar across species.

“After conducting our research with 20 human participants and 10 rats, our results suggest that the optimal tempo for beat synchronization depends on the time constant in the brain,” said Takahashi. “This demonstrates that the animal brain can be useful in elucidating the perceptual mechanisms of music.”

The rats were fitted with wireless, miniature accelerometers, which could measure the slightest head movements. Human participants also wore accelerometers on headphones. They were then played one-minute excerpts from Mozart’s Sonata for Two Pianos in D Major, K. 448, at four different tempos: Seventy-five percent, 100%, 200% and 400% of the original speed.

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This describes the essential Musk — with the caveat that it leaves out his autism and emotional fragility. He has the right philosophy and the brains to make serious progress, but with some surprisingly unexpected naïve schoolboy level mistakes and misunderstandings about human nature. Regardless, he will learn from them.

We may have cracked the code.

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ISRIB, a tiny molecule identified by University of California, San Francisco (UCSF) researchers can repair the neural and cognitive effects of concussion in mice weeks after the damage, according to a new study.

ISRIB blocks the integrated stress response (ISR), a quality control process for protein production that, when activated chronically, can be harmful to cells.

The study, which was recently published in the Proceedings of the National Academy of Sciences, discovered that ISRIB reverses the effects of traumatic brain injury (TBI) on dendritic spines, an area of neurons vital to cognition. The drug-treated mice also showed sustained improvements in working memory.

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A new study shows that the higher vulnerability of evening chronotype individuals (individuals with the propensity to be more productive at night or at dawn) to anxiety and related disorders may be mediated by altered emotional learning.

Chronotypes are our circadian preference profiles; that is, they refer to the differences in performance that each person has in relation to the periods of sleep and wakefulness throughout the 24 hours of the day. We can be morning types if we prefer to wake up early and we have good performance in activities that start in the morning; types if we are more productive at night or at dawn, and prefer to stay up later); or intermediate if we easily adapt to morning and evening schedules.

Circadian rhythms have been increasingly studied because they can help to understand the onset of mental disorders such as anxiety and (PTSD). In this vein, researchers Chiara Lucifora, Giorgio M. Grasso, Michael A. Nitsche, Giovanni D’Italia, Mauro Sortino, Mohammad A. Salehinejad, Alessandra Falzone, Alessio Avenanti and Carmelo M. Vicario consulted the classic Pavlovian paradigm of fear conditioning to study the neurocognitive basis of the association between chronotype and in healthy humans.

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“Colorado voters saw the benefit of regulated access to natural medicines, including psilocybin, so people with PTSD, terminal illness, depression, anxiety and other mental health issues can heal,” co-proponents, Kevin Matthews and Veronica Lightening Horse Perez said in emailed statement Wednesday evening.”

Ten years after legalizing the use and sale of marijuana, Colorado became only the second state in the U.S. to legalize the use of psilocybin mushrooms.

The ballot measure, Proposition 122, squeaked across the finish line as ballots were tallied the day after Election Day, receiving 51% of the vote.

Proponents called it a “truly historic moment.”

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Summary: Using monoclonal antibodies instead of conventional immunosuppressant drugs preserves stem cells in mouse brains.

Source: University of Michigan.

A new approach to stem cell therapy that uses antibodies instead of traditional immunosuppressant drugs robustly preserves cells in mouse brains and has potential to fast-track trials in humans, a Michigan Medicine study suggests.

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