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Revolutionizing Brain Health: Rice University Unveils Tiny, Implantable Brain Stimulator

Rice University engineers have developed the smallest implantable brain stimulator demonstrated in a human patient. Thanks to pioneering magnetoelectric power transfer technology, the pea-sized device developed in the Rice lab of Jacob Robinson in collaboration with Motif Neurotech and clinicians Dr. Sameer Sheth and Dr. Sunil Sheth can be powered wirelessly via an external transmitter and used to stimulate the brain through the dura ⎯ the protective membrane attached to the bottom of the skull.

The device, known as the Digitally programmable Over-brain Therapeutic (DOT), could revolutionize treatment for drug-resistant depression and other psychiatric or neurological disorders by providing a therapeutic alternative that offers greater patient autonomy and accessibility than current neurostimulation-based therapies and is less invasive than other brain-computer interfaces (BCIs).

Pupil Dilation Linked to Working Memory Capacity

Summary: Researchers discovered that pupil dilation can indicate levels of working memory. In a study, researchers observed that individuals whose pupils dilated more while performing memory tasks tended to have better working memory.

This relationship between pupil dilation and memory performance suggests that pupil metrics could potentially serve as non-invasive indicators of cognitive load and memory capacity. The study involved 179 undergraduate students who performed various working memory tasks while their pupil responses were monitored.

New Research Reveals That Trauma Can Get “Under the Skin,” Weakening Your Muscles As You Age

A study from the University of Michigan has shown that traumatic experiences during childhood may get “under the skin” later in life, impairing the muscle function of people as they age.

The study examined the function of skeletal muscle of older adults paired with surveys of adverse events they had experienced in childhood. It found that people who experienced greater childhood adversity, reporting one or more adverse events, had poorer muscle metabolism later in life. The research, led by University of Michigan Institute for Social Research scientist Kate Duchowny, is published in Science Advances.

Duchowny and her co-authors used muscle tissue samples from people participating in the Study of Muscle, Mobility and Aging, or SOMMA. The study includes 879 participants over age 70 who donated muscle and fat samples as well as other biospecimens. The participants also were given a variety of questionnaires and physical and cognitive assessments, among other tests.

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