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A first-of-its-kind study led by the University of California, Irvine has revealed a new culprit in the formation of brain hemorrhages that does not involve injury to the blood vessels, as previously believed. Researchers discovered that interactions between aged red blood cells and brain capillaries can lead to cerebral microbleeds, offering deeper insights into how they occur and identifying potential new therapeutic targets for treatment and prevention.

The findings, published online in the Journal of Neuroinflammation, describe how the team was able to watch the process by which stall in the brain capillaries and then observe how the hemorrhage happens. Cerebral microbleeds are associated with a variety of conditions that occur at higher rates in older adults, including hypertension, Alzheimer’s disease and ischemic stroke.

“We have previously explored this issue in , but our current study is significant in expanding our understanding of the mechanism by which cerebral microbleeds develop,” said co-corresponding author Dr. Mark Fisher, professor of neurology in UCI’s School of Medicine. “Our findings may have profound clinical implications, as we identified a link between red blood cell damage and cerebral hemorrhages that occurs at the capillary level.”

Advancements in genetic engineering, gene therapies, and anti-aging research may eventually allow for age reversal and the restoration of youthful health and longevity.

What is the key idea of the video?
—The key idea is that advancements in genetic engineering and anti-aging research may eventually allow for age reversal and the restoration of youthful health and longevity.

How can aging be reversed?
—Aging can be reversed through rejuvenating the brain, restoring memories and learning abilities, and addressing the loss of inherited information through genetic engineering and epigenetic reprogramming.

A fundamental question in neuroscience is what are the constraints that shape the structural and functional organization of the brain. By bringing biological cost constraints into the optimization process of artificial neural networks, Achterberg, Akarca and colleagues uncover the joint principle underlying a large set of neuroscientific findings.

Is reality indistinguishable from information? Is consciousness a self-aware, self-modifying information field? Does information have intrinsic meaning? How does meaningfulness arise? How do sentient and non-sentient entities differ in the way they perceive and process information?…

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Introduction:

Researchers at the University of Pittsburgh and KU Leuven have discovered a suite of genes that influence head shape in humans. These findings, published this week in Nature Communications, help explain the diversity of human head shapes and may also offer important clues about the genetic basis of conditions that affect the skull, such as craniosynostosis.

By analyzing measurements of the cranial —the part of the skull that forms the rounded top of the head and protects the brain—the team identified 30 regions of the genome associated with different aspects of head , 29 of which have not been reported previously.

“Anthropologists have speculated and debated the genetics of cranial vault shape since the early 20th century,” said co-senior author Seth Weinberg, Ph.D., professor of oral and craniofacial sciences in the Pitt School of Dental Medicine and co-director of the Center for Craniofacial and Dental Genetics.

In an article published yesterday in MIT Technology Review, Rachel Nuwer wrote a thought provoking piece exploring the boundaries between life and death.


Beyond the brain and brain death itself, related efforts are studying and attempting to develop techniques for restoring metabolic function in a number of organs other than the brain after death, including the heart and kidneys, which could greatly enhance organ donation capabilities.

While these developments are promising, researchers caution against overpromising. The path to these medical advancements is paved with years of research and ethical considerations. The exploration into the dying process will surely challenge not only scientific and medical fields but also societal, theological, and legal considerations, as it reshapes our understanding of one of life’s most profound phenomena. At some point, policy and regulations will need to follow—further adding to the complexity of the topic.

The transition from life to death is becoming increasingly blurred as scientific research uncovers previously unknown or poorly understood complexities about the physiology and reversibility of the dying process. This evolving understanding promises to redefine medical practices, extend the window for organ recovery, and challenge our societal notions of life and death. However, this is a true journey, in the sense that the science and its implications will necessarily involve continuous research, ethical and legal considerations, and a need for realistic expectations. While death is a universal experience, what it is and how we go from living to dying are anything but static.

Abrain is nothing if not communicative. Neurons are the chatterboxes of this conversational organ, and they speak with one another by exchanging pulses of electricity using chemical messengers called neurotransmitters. By repeating this process billions of times per second, a brain converts clusters of chemicals into coordinated actions, memories, and thoughts.

Researchers study how the brain works by eavesdropping on that chemical conversation. But neurons talk so loudly and often that if there are other, quieter voices, it might be hard to hear them.

Are gamers paving the way to the future?


The future is now — or so it seems. @perrikaryal is a gamer, Twitch streamer, psychology graduate and a genius with the ability to control games…with her mind! She has mastered the art of doing this with games like Elden Ring, Halo and TrackMania all without using a controller. To do this she uses an EEG (electroencephalogram) that picks up her brain activity, which then translates into pushing buttons on a virtual controller.

Is mind control the future of gaming?

00:00 Intro.
00:20 What is mind control gaming?
01:03 What does brain activity look like?
02:08 How did you make it work?
04:02 James steps in the gaming ring.
05:30 Mind control gaming IS for everyone.
07:42 Bloopers!

#Games #Twitch #Brain.

Researchers from the Faculty of Medicine and Surgery at the Catholic University, Rome and the Fondazione Policlinico Universitario A. Gemelli IRCCS have developed an engineered protein that boosts memory.

Neuroscientists at the Faculty of Medicine and Surgery of the Catholic University, Rome, and the Fondazione Policlinico Universitario Agostino Gemelli IRCCS have genetically modified a molecule, the protein LIMK1, which is normally active in the brain, with a key role in memory.

They added a “molecular switch” that is activated by administering a drug, rapamycin, known for its several anti-aging effects on the brain.