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Is reality indistinguishable from information? Is consciousness a self-aware, self-modifying information field? Does information have intrinsic meaning? How does meaningfulness arise? How do sentient and non-sentient entities differ in the way they perceive and process information?…

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Researchers at the University of Pittsburgh and KU Leuven have discovered a suite of genes that influence head shape in humans. These findings, published this week in Nature Communications, help explain the diversity of human head shapes and may also offer important clues about the genetic basis of conditions that affect the skull, such as craniosynostosis.

By analyzing measurements of the cranial —the part of the skull that forms the rounded top of the head and protects the brain—the team identified 30 regions of the genome associated with different aspects of head , 29 of which have not been reported previously.

“Anthropologists have speculated and debated the genetics of cranial vault shape since the early 20th century,” said co-senior author Seth Weinberg, Ph.D., professor of oral and craniofacial sciences in the Pitt School of Dental Medicine and co-director of the Center for Craniofacial and Dental Genetics.

In an article published yesterday in MIT Technology Review, Rachel Nuwer wrote a thought provoking piece exploring the boundaries between life and death.


Beyond the brain and brain death itself, related efforts are studying and attempting to develop techniques for restoring metabolic function in a number of organs other than the brain after death, including the heart and kidneys, which could greatly enhance organ donation capabilities.

While these developments are promising, researchers caution against overpromising. The path to these medical advancements is paved with years of research and ethical considerations. The exploration into the dying process will surely challenge not only scientific and medical fields but also societal, theological, and legal considerations, as it reshapes our understanding of one of life’s most profound phenomena. At some point, policy and regulations will need to follow—further adding to the complexity of the topic.

The transition from life to death is becoming increasingly blurred as scientific research uncovers previously unknown or poorly understood complexities about the physiology and reversibility of the dying process. This evolving understanding promises to redefine medical practices, extend the window for organ recovery, and challenge our societal notions of life and death. However, this is a true journey, in the sense that the science and its implications will necessarily involve continuous research, ethical and legal considerations, and a need for realistic expectations. While death is a universal experience, what it is and how we go from living to dying are anything but static.

Abrain is nothing if not communicative. Neurons are the chatterboxes of this conversational organ, and they speak with one another by exchanging pulses of electricity using chemical messengers called neurotransmitters. By repeating this process billions of times per second, a brain converts clusters of chemicals into coordinated actions, memories, and thoughts.

Researchers study how the brain works by eavesdropping on that chemical conversation. But neurons talk so loudly and often that if there are other, quieter voices, it might be hard to hear them.

Are gamers paving the way to the future?


The future is now — or so it seems. @perrikaryal is a gamer, Twitch streamer, psychology graduate and a genius with the ability to control games…with her mind! She has mastered the art of doing this with games like Elden Ring, Halo and TrackMania all without using a controller. To do this she uses an EEG (electroencephalogram) that picks up her brain activity, which then translates into pushing buttons on a virtual controller.

Is mind control the future of gaming?

Researchers from the Faculty of Medicine and Surgery at the Catholic University, Rome and the Fondazione Policlinico Universitario A. Gemelli IRCCS have developed an engineered protein that boosts memory.

Neuroscientists at the Faculty of Medicine and Surgery of the Catholic University, Rome, and the Fondazione Policlinico Universitario Agostino Gemelli IRCCS have genetically modified a molecule, the protein LIMK1, which is normally active in the brain, with a key role in memory.

They added a “molecular switch” that is activated by administering a drug, rapamycin, known for its several anti-aging effects on the brain.

An international team of researchers has provided valuable insights into the brain’s noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety.

Equally important beyond the findings is the groundbreaking methodology that the researchers developed to record real-time chemical activity from standard clinical electrodes which are routinely implanted for epilepsy monitoring.

Published online in the journal Current Biology on Monday (Oct. 23), the research not only provides new insights into the brain’s chemistry, which could have implications for a wide array of medical conditions, it also highlights a remarkable new capacity to acquire data from the living human brain.

The researchers used human stem cells to create a model of early brain development — organoids.


Super-resolution image of human stem cell-derived Microglia cells with labeled mitochondria (yellow), nucleus (magenta), and actin filaments (cyan). These Microglia cells help in the maturation of neurons in human brain organoid models. Photo credit: A*STAR’s SIgN

An international team of scientists has uncovered the vital role of microglia, the immune cells in the brain that acts as its dedicated defense team, in early human brain development.

This is almost like endowing a printer with a set of eyes and a brain, where the eyes observe what is being printed, and then the brain of the machine directs it as to what should be printed next.


Moritz Hocher.

Traditional systems use nozzles to deposit tiny drops of resin, smoothed over with a scraper or roller and then curved with UV light. However, this smoothing limits the materials that could be used since slow-curing resins could be squished or smeared.