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Category: neuroscience – Page 116

(THE CONVERSATION) Racism steals time from people’s lives – possibly because of the space it occupies in the mind.

Question Is racial discrimination associated with brain connectivity, and are alterations in deep brain functional connectivity associated with accelerated epigenetic aging?

Findings In this cohort study of 90 Black women in the US, higher self-reported racial discrimination was associated with greater resting-state functional connectivity (RSFC) between the locus coeruleus (LC) and precuneus. Significant indirect effects were observed for the association between racial discrimination frequency and DNA methylation age acceleration.

Meaning These findings suggest that racial discrimination is associated with greater connectivity in pathways involved with rumination, which may increase vulnerability to stress-related disorders and neurodegenerative disease via epigenetic age acceleration.

Continue reading “Racial Discrimination, Neural Connectivity, and Epigenetic Aging in Black Women” | >

Researchers at the University of California, Davis have developed a rapid, noninvasive tool to track the neurons and biomolecules activated in the brain by psychedelic drugs. The protein-based tool, which is called Ca2+-activated Split-TurboID, or CaST, is described in research published in Nature Methods.

There has been mounting interest in the value of psychedelic-inspired compounds as treatments for brain disorders including depression, and . Psychedelic compounds like LSD, DMT and psilocybin promote the growth and strengthening of neurons and their connections in the brain’s prefrontal cortex. The new tool could help scientists unlock the benefits of psychedelic treatments for patients with brain disorders.

“It’s important to think about the that these psychedelics act upon,” said Christina Kim, an assistant professor of neurology at the UC Davis Center for Neuroscience and School of Medicine, and an affiliate of the UC Davis Institute for Psychedelics and Neurotherapeutics. “What are they? Once we know that, we can design different variants that target the same mechanism but with fewer side effects.”

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Mental effort is generally unpleasant, as confirmed by a meta-analysis involving over 4,600 participants across various tasks and demographics. People often pursue challenging activities for the rewards, not the pleasure of the task. Credit: SciTechDaily.com.

A meta-analysis of 170 studies revealed that regardless of the task or population, increased mental effort correlates with feelings of frustration and stress. This phenomenon is less pronounced in Asian populations, possibly due to different educational experiences. Despite this, people still engage in mentally challenging tasks like chess, driven by the rewards rather than enjoyment of the effort itself.

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Science: Physicists Will conduct experiments to verify if we live in the real reality or if we live in a virtual reality. In a computer simulation. In a dream. Or if not.

Researchers at California State Polytechnic University (CalPoly), Pomona are carrying out a series of quantum physics experiments expected to provide strong scientific evidence that we live in a computer simulated virtual reality. — PR13031782.

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Our brain measures time by counting experiences, not by following a strict chronological order.

A new study by a team of UNLV researchers suggests that there’s a lot of truth to the trope “time flies when you’re having fun.”

In their study, recently published in the journal Current Biology, the researchers discovered that our perception of time is based on the number of experiences we have, not on an internal clock. Additionally, they found that increasing speed or output during an activity appears to affect how our brains perceive time.

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Summary: Researchers developed a computer model that mimics how the hippocampus stores new episodic memories without erasing old ones. This model demonstrates that the CA3 region of the hippocampus serves as an anchor point for memories, allowing efficient storage in surrounding regions.

The findings reveal insights into how the brain organizes personal experiences and maintains stability despite constant updates. The model shows promise for enhancing our understanding of memory retention and cognitive processing.

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