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“It’s a known phenomenon, but it was never fully understood,” said Yukun Liu, the study’s first author and a Ph.D. candidate in Dravid’s laboratory. “Because you really need to be able to combine the direct visualization of water generation and the structure analysis at the atomic scale in order to figure out what’s happening with the reaction and how to optimize it.”

But viewing the process with atomic precision was simply impossible—until nine months ago. In January 2024, Dravid’s team unveiled a novel method to analyze gas molecules in real time. Dravid and his team developed an ultra-thin glassy membrane that holds gas molecules within honeycomb-shaped nanoreactors, so they can be viewed within high-vacuum transmission electron microscopes.

With the new technique, previously published in Science Advances, researchers can examine samples in atmospheric pressure gas at a resolution of just 0.102 nanometers, compared to a 0.236-nanometer resolution using other state-of-the-art tools. The technique also enabled, for the first time, concurrent spectral and reciprocal information analysis.

Many vaccines, including vaccines for hepatitis B and whooping cough, consist of fragments of viral or bacterial proteins.


“Not only are we delivering the protein in a more controlled way through a nanoparticle, but the compositional structure of this particle is also acting as an adjuvant,” Jaklenec says. “We were able to achieve very specific responses to the Covid protein, and with a dose-sparing effect compared to using the protein by itself to vaccinate.”

Vaccine access

While this study and others have demonstrated ZIF-8’s immunogenic ability, more work needs to be done to evaluate the particles’ safety and potential to be scaled up for large-scale manufacturing. If ZIF-8 is not developed as a vaccine carrier, the findings from the study should help to guide researchers in developing similar nanoparticles that could be used to deliver subunit vaccines, Jaklenec says.

Battery performance is heavily influenced by the non-uniformity and failure of individual electrode particles. Understanding the reaction mechanisms and failure modes at nanoscale level is key to advancing battery technologies and extending their lifespan. However, capturing real-time electrochemical evolution at this scale remains challenging due to the limitations of existing sensing methods, which lack the necessary spatial resolution and sensitivity.

Arizona-based startup Mechnano has exited “stealth mode” in the research and development of its carbon nanotube (CNT) technology for 3D printing materials.

The company has developed its first product, an electrostatic discharge (ESD) resin that delivers dissipative properties to 3D printed parts without compromising mechanical properties.

“These are extraordinary breakthroughs for additive manufacturing materials,” said Steven Lowder, Mechnano’s Founder and CEO. “By focusing on the nanoscale, or the molecular level, we are able to make exponential improvements in AM materials at the macro-level.

A new technology to continuously place individual atoms exactly where they are needed could lead to new materials for devices that address critical needs for the field of quantum computing and communication that cannot be produced by conventional means, say scientists who developed it.

A research team at the Department of Energy’s Oak Ridge National Laboratory created a novel advanced microscopy tool to “write” with atoms, placing those atoms exactly where they are needed to give a material new properties.

“By working at the atomic scale, we also work at the scale where quantum properties naturally emerge and persist,” said Stephen Jesse, a materials scientist who leads this research and heads the Nanomaterials Characterizations section at ORNL’s Center for Nanophase Materials Sciences, or CNMS. “We aim to use this improved access to quantum behavior as a foundation for future devices that rely on uniquely quantum phenomena, like entanglement, for improving computers, creating more secure communications and enhancing the sensitivity of detectors.”

While current treatments for ailments related to aging and diseases like type 2 diabetes, Alzheimer’s, and Parkinson’s focus on managing symptoms, Texas A&M researchers have taken a new approach to fight the battle at the source: recharging mitochondrial power through nanotechnology.

Led by Dr…


When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body?

When we need to recharge, we might take a vacation or relax at the spa. But what if we could recharge at the cellular level, fighting against aging and disease with the microscopic building blocks that make up the human body?

The ability to recharge cells diminishes as humans age or face diseases. Mitochondria, often called the powerhouse of the cell, are central to energy production. When mitochondrial function declines, it leads to fatigue, tissue degeneration, and accelerated aging. Activities that once required minimal recovery now take far longer, highlighting the role that these organelles play in maintaining vitality and overall health.

While current treatments for ailments related to aging and diseases like type 2 diabetes, Alzheimer’s, and Parkinson’s focus on managing symptoms, Texas A&M researchers have taken a new approach to fight the battle at the source: recharging mitochondrial power through nanotechnology.