Lifeboat Foundation

#biophotonics #photonics

ONNA, Japan, Jan. 13, 2020 — Scientists at the Okinawa Institute of Science and Technology (OIST) Graduate University have developed a light-based device that can act as a biosensor, detecting biological substances in materials, such as harmful pathogens in food. The scientists said that their tool, an optical microresonator, is 280× more sensitive than current industry-standard biosensors, which can detect only cumulative effects of groups of particles, not individual molecules.

To detect the quantum friction of empty space, scientists are going for a spin.

A twirling nanoparticle, suspended in a laser beam inside of a vacuum, can measure tiny twisting forces, making it the most sensitive detector of torque yet created. Researchers say the device could one day detect an elusive quantum effect called vacuum friction.

The suspended nanoparticle can spin more than 300 billion times a minute. “This is the fastest human-made rotor in the world,” says physicist Tongcang Li of Purdue University in West Lafayette, Ind.

Drastic miniaturization of electronics and ingression of next-generation nanomaterials into space technology have provoked a renaissance in interplanetary flights and near-Earth space exploration using small unmanned satellites and systems. As the next stage, the NASA’s 2015 Nanotechnology Roadmap initiative called for new design paradigms that integrate nanotechnology and conceptually new materials to build advanced, deep-space-capable, adaptive spacecraft. This review examines the cutting edge and discusses the opportunities for integration of nanomaterials into the most advanced types of electric propulsion devices that take advantage of their unique features and boost their efficiency and service life. Finally, we propose a concept of an adaptive thruster.

Interesting research paper on a new nanobot technology. I’m watching for ways in which suitable substrates for mind uploading can be constructed, and DNA self-guided assembly has potential.

Here are some excerpts and a weblink to the paper:

“…Chemical approaches have opened synthetic routes to build dynamic materials from scratch using chemical reactions, ultimately allowing flexibility in design…”

Continue reading “Dynamic DNA material with emergent locomotion behavior powered by artificial metabolism” »

An international team of cancer researchers has developed a new type of copper-based nanoparticle that can kill tumor cells in mice. While the technology showed effectiveness on its own, by combining it with immunotherapy the scientists say it produced long-lasting effects, quickly killing off any cancer cells that dared to return.

The therapy centers on new knowledge around tumors’ aversion to certain types of nanoparticles. The research team made up of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina, discovered that tumor cells were particularly sensitive to nanoparticles made from copper and oxygen.

Once these copper oxide nanoparticles enter a living organism they dissolve and become toxic, killing off cancer cells that happen to be in the area. Key to the new nanoparticle design was the addition of iron oxide, which the researchers say enables it to kill off cancer cells while leaving healthy cells intact.

Circa 2013

A new metamaterial is the first with a refractive index near zero, allowing light waves to propagate ultrafast over nano-distances.

Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a “suicide gene” to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals’ survival.

In their study, described in a report published January 2020 in the journal Nanomedicine: Nanotechnology, Biology and Medicine, the researchers caution that for safety and biological reasons, it is unlikely that the suicide gene herpes simplex virus type I thymidine kinase (HSVtk)—which makes tumor cells more sensitive to the lethal effects of the anti-viral drug ganciclovir—could be the exact therapy used to treat human medulloblastoma and atypical teratoid/rhabdoid tumors (AT/RT) in children.

So-called “suicide genes” have been studied and used in cancer treatments for more than 25 years. The HSVtk gene makes an enzyme that helps restore the function of natural tumor suppression.

Optically levitated nanosphere shows definitive signature of its quantum ground state of motion.

Picture a marble rolling around inside a bowl. The motion of the marble represents its center-of-mass temperature, a quantity distinct from the object’s physical temperature. Now replace the marble with a levitated nanosphere and the bowl with an optical trap, and you have the experiment used by Felix Tebbenjohanns and colleagues at the Swiss Federal Institute of Technology (ETH), Zurich, to reduce a levitated nanoparticle’s center-of-mass temperature to close to its quantum ground state. The experimental signature showing that the nanosphere had entered the quantum regime had, until now, been seen only in mechanically clamped systems coupled to optical cavities.

This technology may one day be used to revive patient suspended in cryonics.

A new way to warm up frozen tissue using tiny vibrating particles could one day help with the problem of organ shortages.

We know how to cool organs to cryogenic temperatures, which is usually below 320 degrees Fahrenheit. But the organs can’t be stored for long — sometimes only four hours for heart and lungs — because they get damaged when you try to warm them up. As a result, more than 60 percent of donor hearts and lungs aren’t transplanted. In a study published today in Science Translational Medicine, scientists used nanoparticles to warm up frozen tissue quickly and without damaging the organs. Within a decade, this could lead to being able to store entire organs in organ banks for a long period of time, the authors say.

Continue reading “A new way to warm up frozen tissue could help with the organ shortage” »