A new Aubrey de Grey podcast about the work SENS RF is conducting to cure age related diseases.
On today’s episode of Bulletproof Radio Dave and aging expert Aubrey de Grey talk about the 7 aging causes, morbidity & the ethics of immortality. Enjoy!
Category: life extension – Page 651
Project | 21 — We Can End Aging
Website: http://sensproject21.org/
Building the bridge to human clinical trials for rejuvenation biotechnologies.
INTERNET ENTREPRENEUR MICHAEL GREVE COMMITS $10 MILLION TO SENS RELATED RESEARCH AND STARTUPS INCLUDING A $5 MILLION DONATION OVER 5 YEARS TO SENS RESEARCH FOUNDATION.
The social and economic burdens of age-related disease are rising steeply. For an increasing number of older individuals, healthcare is too often reduced to crisis management in the emergency room, painfully harsh treatments for diseases such as cancer, or best efforts at palliative care.
It doesn’t have to be this way.
Project|21 is a new initiative created by SENS Research Foundation to end age-related disease through human clinical trials, starting in 2021, through investment in rejuvenation biotechnology. We have all the pieces in place–core research groups, key players, shared knowledge, and underlying tools—for the creation of this industry. Through three new programs, the Bridge fund, The Center of Excellence, and The Alliance Program, Project|21 will deliver the perfect environment for this fusion of opportunity and investment. With proper stewardship of this emerging industry, we can create an environment where the first damage repair interventions to address specific age-related disease will be brought to human clinical trials within five years.
Genomics maverick Craig Venter’s plan to unlock DNA’s connection to disease
Awesome! Just imagine all the benefits that we will see through this research. Not only will we figure out more on the root cause of gene mutations, and cures including CRISPR; but also we will be more effective in mimicking the human system in synthetic systems, synthetic cell or gene circuitry, humanoids, synthetic immune systems, combat aging more effectively, etc.
With more data, a pioneer of gene sequencing hopes to unlock the connections between DNA and illness.
Project|21 SENS Research Foundation | Building the Bridge to Human Clinical Trials for Rejuvenation Biotechnologies
MOUNTAIN VIEW, Calif. — July 11, 2016 — SENS Research Foundation today announced its Project|21 campaign to secure $50 million in private support from individual donors, foundations, and corporations. The goal of Project|21 is for SRF to partner with a new generation of visionary philanthropists, build the Rejuvenation Biotechnology industry, and bridge the most challenging gulf between research and treatment by enabling human clinical trials by 2021.
Aubrey de Grey, founder and chief science officer of SENS Research Foundation said, “Ending aging will require large-scale investment to flow into a globally-recognized industry for rejuvenation biotechnology. Since we began in 2009, SENS Research Foundation has been putting all the pieces in place — core research groups, key players, shared knowledge, underlying tools — for the creation of this industry. The key programs funded by Project|21 can create an environment where the first damage repair interventions addressing specific age-related diseases will be brought to human clinical trials within five years.”
The programs funded under Project|21 focus on three major barriers to the development of truly effective rejuvenation therapies. First, funding to convert promising basic research programs into solid investment candidates remains far too scarce. Second, there are too few opportunities for dynamic collaborations with mainstream regenerative medicine. Finally, there is little understanding of the regulatory pathways and clinical infrastructure these technologies will require. Project|21 addresses these three areas by creating a $15 million bridge fund to support promising early stage technologies; a center of excellence to deliver better opportunities for collaborative development of early stage programs; and a Rejuvenation Biotechnology Alliance Program to address challenges in regulation, manufacturing, and investment.
The first donation received for Project|21 is a commitment from German internet entrepreneur Michael Greve’s Forever Healthy Foundation for $5 million in philanthropic support over the next five years. In addition Michael Greve’s company KIZOO Technology Ventures will be committing seed investments of $5 million in startups focused on bringing rejuvenation biotechnology treatments to market.
For more information on the SENS Research Foundation visit www.sens.org. For information on Project|21 visit www.SENSProject21.org. For information on Michael Greve visit www.kizoo.com and www.forever-healthy.org.
Companion Press Release: “Internet Entrepreneur Michael Greve Commits $10 Million to SENS Related Research and Startups including a $5 Million Donation Over 5 Years to SENS Research Foundation.”
Ray Kurzweil Outlines the Coming Biomedical Revolution [Video]
Will we live longer lives in the future? According to Ray Kurzweil, it’s only a matter of time until technology begins successfully tackling age-related disease—and life expectancy grows longer and longer. At some point, technology will annually add more than a year to our life expectancy—allowing us to indefinitely increase lifespans, and perhaps eventually live as long as we want.
“We will get to a point where our longevity, our remaining life expectancy is moving on away from us. The sands of time will run in rather than run out,” Kurzweil says.
How will this happen? We’re now learning to reprogram biology to cure disease and repair the body. This will accelerate in coming decades and be followed by the nanotechnology revolution.
Study shows continuous dehydration kills cells during dry preservation
A new finding in experiments studying the dry preservation of living cells — a potentially revolutionary alternative to cryopreservation — has defined a clear limit where continuing dehydration kills cells. The data, combined with molecular dynamics simulations, provides insight into an important processing factor that has limited recent attempts at dry preservation.
“What we have done is identified what appears to be a materials constraint in our method of dry preservation. I think this new understanding suggests some interesting avenues to pursue in developing a successful process,” said Gloria Elliott, Professor of Mechanical Engineering at the University of North Carolina at Charlotte, one of the study’s authors.
The findings, reported in the July 8 issue of Scientific Reports, analyzes changes in the molecular arrangements of trehalose (a sugar) and water molecules during a typical dehydration process that they use to immobilize cells in a stable trehalose glass for long-term storage.
Matching Fund Donors Sought for SENS Universal Cancer Therapy Crowdfunding
SENS has a fund match for its current campaign on lifespan.io, if you are concerned about cancer like me and you want to help directly fund a lab working on solutions please think about donating. smile
There is a month left to go in the SENS crowdfunding campaign that aims to accelerate development of an important component of a universal cancer therapy, a way to block the mechanisms of telomere lengthening that every type of cancer depends upon. The SENS Research Foundation and Lifespan.io volunteers are looking for donors to put up matching funds of a few thousand dollars or more, in order to take that news and that inducement to a number of conferences and other events over the next few weeks. More than 150 people have donated to the campaign to date, and we’d like to triple that number in the next 30 days.
To start things off, I’ll offer up $2,000 of my own funds: the next $2,000 in donations to this SENS cancer research initiative will be matched dollar for dollar. That is a start, and if you can join in to help out, please contact me to let me know. Can you help to make a difference here?
With last week’s $10 million pledge in support of other portions of the SENS rejuvenation research portfolio, we can clearly see that grassroots fundraising works. It lights the way, and as we grow the community and show our determination, that success draws in larger donors. When this is amply demonstrated by the arrival of large amounts of new funding … well, that is precisely the time to pile on and keep up the good work. All major medical research non-profits have several tiers of fundraising, from grassroots to high net work philanthropy, and all of these tiers are essential: they can’t exist without one another. The SENS Research Foundation is transitioning to become a solid organization with a high end tier of fundraising to complement our efforts, and that couldn’t exist without the support of the grassroots. It is a sign that we are winning.
Stanford Researchers ‘Trick’ Human Stem Cells To Regenerate Faster
Researchers at the Stanford University School of Medicine found a way to trick human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days.
Scientists at the Stanford University School of Medicine have identified the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells. If successful, researchers could grow pure populations of any of 12 cell types, including bone, heart muscle and cartilage within days rather than the weeks or months previously required.
This is key toward clinically useful regenerative medicine – potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.
Atheist Presidential Candidate: Religion is Literally Killing Us
It’s not just religious terrorism that is killing people. A religious anti-science culture—which most of us live amongst—also cuts short everyone’s lives. People simply don’t care much about longevity if they believe in an afterlife.
All around the world, religious terror is striking and threatening us. Whether in France, Istanbul, London, or the USA, the threat is now constant. We can fight it all we want. We can send out our troops; we can chip refugees; we can try to monitor terrorist’s every move. We can even improve trauma medicine to deal with extreme violence they bring us. But none of this solves the underlying issue: Abrahamic religions like Christianity and Islam are fundamentally violent philosophies with violent Gods. Sam Harris, Richard Dawkins, Christopher Hitchens and others have all reiterated essentially the same thing.
Consider these verses from the Koran:
Koran (3:56): As to those who reject faith, I will punish them with terrible agony in this world and in the Hereafter, nor will they have anyone to help.
Koran (8:12): I will cast terror into the hearts of those who disbelieve. Therefore strike off their heads and strike off every fingertip of them.