Lifeboat Foundation

UNSW researchers have identified a critical step in the molecular process that allows cells to repair damaged DNA – and it could mean big things for the future of anti-ageing drugs, childhood cancer survivors and even astronauts. It could lead to a revolutionary drug that actually reverses ageing, improves DNA repair and could even help NASA get its astronauts to Mars.

Their experiments in mice suggest a treatment is possible for DNA damage from ageing and radiation. It is so promising it has attracted the attention of NASA, which believes the treatment can help its Mars mission.

While our cells have an innate capability to repair DNA damage − which happens every time we go out into the sun, for example – their ability to do this declines as we age.

Continue reading “Critical step in cellualr repair of damaged DNA identifi edwhich could be big for reversing aging and human trials will start within six months” »

Researchers have identified a cellular mechanism that allows them to reverse ageing in mouse DNA and protect it from future damage.

They’ve shown that by giving a particular compound to older mice, they can activate the DNA repair process and not only protect against future damage, but repair the existing effects of ageing. And they’re ready to start testing in humans within six months.

“The cells of the old mice were indistinguishable from the young mice, after just one week of treatment,” said lead researcher David Sinclair from the University of New South Wales (UNSW) in Australia and the Harvard Medical School in Boston.

Continue reading “It’s Happening: Scientists Can Now Reverse DNA Ageing in Mice” »

A team of researchers from the University of New South Wales in Australia have discovered a key molecular process in DNA repair that could stop cells from ageing and help DNA to reverse damage.

Nice summary from Wired on Liz.

After her son was diagnosed with type 1 diabetes, Elizabeth Parrish began researching gene therapy treatments. She then started testing them on herself.

Scientists in Germany have discovered a protein that can prompt the body’s blood stem cells to act young again, potentially reversing some of the bad aspects of the aging process.

The suggestion that young blood may be the key to reversing some of the negative aspects of aging sounds like the setup to a horror movie. In reality, however, it refers to some groundbreaking work being carried out by scientists at the University of Ulm in Germany.

They’ve been examining the ways that old blood can be made young again, and they hypothesize that it might help fight some of the effects of aging. To achieve this, they’ve discovered a protein capable of boosting blood stem cells, which prompt them to act like the stem cells of younger people.

I was under the impression that human trials were already underway, but this says they will start in 6 months.

UNSW researchers have made a discovery that could lead to a revolutionary drug that actually reverses ageing, improves DNA repair and could even help NASA get its astronauts to Mars.

In a paper published in Science today, the team identifies a critical step in the molecular process that allows cells to repair damaged DNA.

Continue reading “Scientists unveil a giant leap for anti-aging” »

Should these results prove to be accurate, it means that scientists have actually managed to create a way to reverse aging.

Longevity news from Sweden.

More pressure to include aging as a disease from a number of important scientists. This time Sweden is the focus for the push to have aging included in their disease classification.

In a world without ageing, our idea of family will likely change—for the better.

So it would, and I’m looking forward to it.

As things stand, this is what happens to a human family in a nutshell. Two people start dating. If things go well, they may want to live together and have kids. The kids grow up and do the same, eventually, and the original parents become grandparents, generally around the time they start being elderly. Unfortunately, this means they are less and less able to take care of themselves (let alone their grandchildren), and thus are more of a burden than a helping hand. (Talk to people who are around 60 and have kids, and you’ll find out their worst concern is being a burden to their families the moment they’re no longer able to take care of themselves.)

Grandparents eventually die. Repeat the process for enough generations, and eventually the members of the original family will all have died—the family is dismantled. Maybe other families originated from it, but it is irrelevant. The people are what matters to us, not their genes. Genes will be passed on, but all the people in the process will die, and become just a carrier for the genes. Looks like we really should have read the fine print before signing up for life, eh?

Continue reading “Rejuvenation would change our concept of family” »