Lifeboat Foundation

A single infusion gene therapy treatment improved levels of the essential blood clotting protein Factor VIII, with 85 percent of patients achieving normal or near-normal levels of the blood clotting factor, even many months after treatment.

Summary: British doctors say they have achieved “mind-blowing” results using gene therapy to rid people of hemophilia A. [This article first appeared on LongevityFacts. Author: Brady Hartman.]

We are one step closer to a cure for hemophilia according to the results of a groundbreaking gene therapy trial published in the New England Journal of Medicine.

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New view on mitochondrial DNA could put the brakes on mutations that drive diseases. Scientists perform landmark sequencing of mitochondrial DNA and discover surprising facts.

Summary: New view on mitochondrial DNA could help put the brakes on mutations that drive diseases. [Author: Brady Hartman. This article first appeared on LongevityFacts.]

DNA sequences between mitochondria inside a single cell are vastly different, reported scientists in the Perelman School of Medicine at the University of Pennsylvania. This discovery will help to illuminate the underlying mechanisms of diseases that start with mutations in mitochondrial DNA and provide clues about how patients might respond to specific treatments. The researchers published their findings in the journal Cell Reports this week.

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https://www.spreaker.com/user/talk4media/beyond-confidence-12-18-2017

Whether or not immortality is possible, whether or not one would like it for oneself, it’s important to keep in mind that it is not what biomedical research against ageing is about.

When doing science, it is crucially important to have clear, unambiguous definitions. These definitions must be firmly established to avoid confusion and misunderstandings and possibly to prevent people from going around telling everyone that you’re working on something that you’re actually not.

The I-word

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Good stuff from Aubrey. One person is a deathist, another is a maybe, the other is pro-life extension.

Turning back the clock and undoing the ravages of time. Something we’ve probably all wondered about — but could it become reality? Or are we all just wishing our lives away?
We may soon be able to stop or even undo the ageing process. By purging the body of so-called ‘retired cells’, scientists say we could look younger, live longer, and defeat disease. Is this science’s answer to the fabled fountain of youth?
At the Roundtable was Aubrey de Grey, Biomedical gerontologist and Chief Science Officer at Sens Research Foundation; Lara Marks, a visiting Research Associate at University College London and Historian of Medicine at King’s College London; Professor Ilaria Bellantuono, Stem cell biologist and Professor in musculoskeletal ageing at the University of Sheffield and journalist Salman Shaheen.
Roundtable is a discussion programme with an edge. Broadcast out of London and presented by David Foster, it’s about bringing people to the table, listening to every opinion, and analysing every point of view. From fierce debate to reflective thinking, Roundtable discussions offer a different perspective on the issues that matter to you. Watch it every weekday at 15:30 GMT on TRT World.

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https://www.spreaker.com/user/wholecarenetwork/aging-90-is-the-new-50

Nextbigfuture interviewed Michael West, CEO of the startup AgeX for nearly three hours today. The key to human regeneration is from week 3 to week 8 after fertilization of the egg when we are an embryo. In week one and week two, we are a zygote. After week, we are fetus.

Nextbigfuture will follow up this article with several more articles with information from the interview. This article will provide the core of the AgeX approach to full regeneration and radical life extension.

2018 announces Program and Speakers!

This conference is focused on the cellular and molecular repair of age-related damage as the basis of therapies to bring aging under full medical control, It will mirror the structure of SENS, with sessions devoted to each strand and to the enabling technologies that multiple strands will rely upon. Sessions will cover a wide range of topics across the damage-repair spectrum.

Further details are given below:

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