Really excited to announce our new initiative to make early-stage rejuvenation therapies more accessible.

Our mission is to enable people to vastly extend their healthy lifespan and be part of the first generation to cure aging.

We support the development of rejuvenation therapies that undo the damage of aging by funding basic research, bringing together the world’s leading scientists at our annual Undoing Aging conference and helping startups that work on actual therapies for human use.

In addition, we are developing our ‘Personal Longevity Strategy’ which harnesses the enormous wealth of the world’s cutting-edge medical knowledge to empower people to make informed decisions about extending their healthy lifespan right now.

Today we are going to take a look at the emerging theory that inflammaging, a chronic, age-related background of inflammation, is caused by alterations to the populations of intestinal microbes.

What is inflammaging?

Inflammaging is a term coined to describe the chronic, smoldering background of inflammation that accompanies the aging process. It is constant, low-grade inflammation that interferes with stem cell mobility, cellular communication, and the immune system’s ability to operate correctly.

One of the most commonly asked questions we receive is “How is progress going in aging research?” It is something we are asked so often that we decided to provide the community with a resource that will help them to keep track of progress directly.

To that end, today we have launched our new curated database, The Rejuvenation Roadmap, which will be tracking the progress of the many therapies and projects in the rejuvenation biotechnology field. This database aims to give a quick visual summary of the status of each drug or therapy along with some additional information for people interested in learning more about them.

We believe that an informed community is an effective one, and this was one of our motivations for developing this new database. There are many resources for scientists, such as the superb databases of the Human Ageing Genomic Resources maintained by Dr. João Pedro de Magalhães, which are excellent for researchers. However, we noticed that there was no database that tracked the efforts of the many researchers and projects in the field, and while some people do maintain lists, they are often not public facing, easy to access, or user-friendly.

Startup, Unity Biotechnology, prevents aging—and it’s not as crazy as it seems.

Now on his fifth startup, Ned David has the blueprint for creating a lucrative biotech. His latest project: a company that will take on the ravages of aging.

A new approach to fight the aging process: rejuvenating the nuclear membrane.

A new discovery about the effects of aging in our cells could allow doctors to cure or prevent diabetes, fatty liver disease and other metabolic diseases — and possibly even turn back the clock on aging itself.

The new finding from the University of Virginia School of Medicine suggests that fatty liver disease and other unwanted effects of aging may be the result of our cells’ nuclei — the compartment containing our DNA — getting wrinkly. Those wrinkles appear to prevent our genes from functioning properly, the UVA researchers found.

There’s no wrinkle cream for nuclear membranes, but there is a tantalizing possibility: We might use viruses to smooth the membranes’ surfaces — and restore the cells to functioning as they did in the glow of youth.