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The authors draw attention to several randomized clinical studies in humans that have found that over the counter supplements such as n-acetylcysteine (NAC), which is used to treat acetaminophen poisoning and is also used as a mucus thinner to help reduce bronchitis exacerbations, and elderberry extracts, have evidence for shortening the duration of influenza by about two to four days and reducing the severity of the infection. The authors also note several nutraceuticals such as spirulina, beta-glucan, glucosamine, and NAC have either been found to reduce the severity of infection or to cut the rate of death in half in animals infected with influenza. Furthermore, one clinical study in humans testing spirulina noted significant reductions in viral load in those infected with HIV.

In a compelling article in Progress in Cardiovascular Diseases, published by Elsevier, Mark McCarty of the Catalytic Longevity Foundation, San Diego, CA, USA, and James DiNicolantonio, PharmD, a cardiovascular research scientist at Saint Luke’s Mid America Heart Institute, Kansas City, MO, USA, propose that certain nutraceuticals may help provide relief to people infected with encapsulated RNA viruses such as influenza and coronavirus.

In the United States, influenza infects around 30 million people every year causing around 30,000 deaths. While there are medications approved for the treatment of influenza, they typically are costly, have side effects, and are not very effective. Additionally, vaccinations against influenza may only be effective in around 50 percent of those vaccinated. Thus, there is a need for safer and effective alternatives in those infected with influenza.

Over the past few months, a novel RNA coronavirus, now called COVID-19, has broken out in China and has spread to over two dozen countries and infected more than 76,000 people causing more than 2,000 deaths. This novel coronavirus is much more lethal than the typical flu, with a current mortality rate of about 2.92 percent. In other words, around 1 in 33 people who are infected with this novel coronavirus will die. Whereas the annual flu has a mortality rate of just 0.05 to 0.1 percent. This means that around 1 in 1,000 to 2,000 people infected with the annual flu will die. In other words, COVID-19 is around 30 to 60 times more lethal than the typical annual flu.

Continue reading “Recent research points the way toward a practical nutraceutical strategy for coping with RNA virus infections including influenza and coronavirus” »

Because of the central importance of tissue repair to all organisms, Neves assumed that many of the mechanisms behind it would be shared among all animals. So she started looking at proteins produced by immune cells in the well-known animal model of the fruit fly.

She discovered that a poorly-understood protein known as MANF (mesencephalic astrocyte-derived neurotrophic factor) plays a crucial role in reducing inflammation in fruit flies. More importantly, she found that mice and humans also produce it, and its prevalence reduces in all the species as they age, suggesting it plays a key role in limiting age-related inflammation.

That prompted her to see if introducing MANF would boost the effectiveness of stem cell treatments in older animals. She used the protein in combination with a procedure that uses stem cells to replace degenerating photoreceptors in the retina of older mice and found it greatly improved the restoration of vision.

I interviewed transhumanist thinker Anders Sandberg, research fellow at Oxford Universities Future of Humanity Institute. We discuss how the global transhumanist movement has changed, the potential political impact of technological revolutions and the debate around cryonics. Fairly new channel so very grateful for any subscribers smile

My interview with Anders Sandberg, a prominent transhumanist thinker and research fellow at the Future of Humanity Institute at Oxford University.

Continue reading “A Transhumanism future? — Anders Sandberg interview” »

Senolitics can be one of the first for one of the causes of ageing. One of the agents that have shown a senolytic effect is fisetin.

Because of the availability and safety of fisetin, we decided to conduct our experiments of this drug in a person with autoimmune thyroiditis. It is noteworthy that, unlike most trials, we focus not on chronic inflammation but on immune function.

For this test, we need your financial help.

Continue reading “Clinical trials of Fisetin in a person with autoimmune thyroiditis” »

March 9 (UPI) — Scientists have developed a technique for repairing damaged DNA. The breakthrough, published this week in the journal Nature Communications, could pave the way for new therapies for cancer and neurodegenerative disorders.

The accumulation of DNA damage is responsible for aging, cancer and neurological diseases like motor neuron disease, also known as ALS.

Until now, scientists have struggled to find ways to repair this kind of damage. However, researchers have discovered a new protein called TEX264 that can combine with other enzymes to find and destroy toxic proteins that bind to DNA and trigger damage.

Hi everyone, thanks for the add. Good to be part of the group. I’ve recently done a video exploring the spiritual implications of radical life extension — which may interest some of you.

Spirituality & Life Extension. In this video I explore modern life and spirituality, in the light of radical life extension, i.e slowing ageing, enhancing longevity, and what that might mean for us in terms of spirituality and well-being. Do you you would continue to be spiritual if you had another healthy century ahead of you?

Continue reading “Spirituality & Life Extension | Pneumanosophy Academy” »

Along with academic research departments around the world, private sector medical technology companies are getting in on the action, seeking ways to increase longevity and health span.

Scientists who study the biology of Aging agreed that we would someday be able to slow down the aging process substantially.

Dr. Aubrey de Grey, Chief Science Officer at SENS Research Foundation and VP of New Technology Discovery at AgeX Therapeutics believes that the critical biomedical technology required to eliminate aging derived debilitation and death is now within reach.

In his book “Ending Aging” he and his research assistant Michael Rae described the details of this biotechnology. They explained that the Aging of the human body, just like the Aging of manmade machines, results from an accumulation of various types of damage. As with manmade machines, this damage can periodically be repaired, leading to the indefinite extension of the machines fully functional lifetime just as is routinely done with classic cars.

Dreams of human immortality may remain so, but extending our lives beyond 100, even 150 years, can soon become a reality. ‘The Future is Now’ explores ground-breaking technology that might help us to slow down the ageing process and overcome our physical limitations.

3D-printing of brand new human organs, controlling bionic prosthetics with your mind, or invading your body with disease-fighting microrobots. Hosts Kate and Talish bring you the latest developments in biomedical engineering.

Continue reading “The Future is Now. Biomedical advances that will change the human body” »