O.o!!! The longevity of this complex organism could reveal new avenues for immortality.
Arenaerpeton supinatus was discovered in rocks cut from a nearby quarry that were intended for the building of a garden wall.
A 240-million-year-old fossil of an amphibian was found in a retaining wall in the 1990s. This significant find has now been formally named and described by scientists at the University of New South Wales (UNSW Sydney) and the Australian Museum.
The fossil was originally discovered by a retired chicken farmer in rocks from a local quarry. These rocks were intended for use in constructing a garden retaining wall, and the fossil was subsequently donated to the Australian Museum in Sydney.
We all know having a balanced diet is important to stay healthy. New research from Waseda University has started to unpick the optimum proportion of macronutrients for a diet that supports metabolic health as we age – starting with protein. The study is published in GeroScience.
Linking diet to “healthspan”
Over our lifespans, our nutrition needs change. By optimizing our diets according to what our bodies need (in relation to our age), we can maintain our metabolic health and thereby increase our “healthspan”, with healthspan referring to the length of time in our lives that we spend in good health.
Brain age was estimated using an algorithm that combined multiple measures of brain structure obtained through MRI scans when the participants were 45 years old. This algorithm quantified the difference between estimated brain age and the participants’ chronological age, referred to as brain age gap estimate.
If the estimated brain age is higher than the chronological age, it suggests that the brain’s structural characteristics are more similar to those of an older individual. Conversely, if the estimated brain age is lower than the chronological age, the brain’s structural characteristics resemble those of a younger individual.
Lay-Yee and his colleagues also adjusted their analyses for various potential confounding factors. These included socio-demographic factors like sex and socio-economic status, as well as family factors (teen-aged mother, single parent, change in residence, maltreatment) and child-behavioral factors (self-control, worry/fearfulness).
The authors used a long-read nanopore method to study chromatin accessibility and DNA methylation of the highly repetitive centromeres, telomeres, and ribosomal DNA arrays in both wildtype and DNA methylation mutants of Arabidopsis.
Dr. Ezekiel Emanuel plans to reject life-extending medical care at the age of 75. The reason he does this is quite similar to why the Kaelons commit ritual suicide in Star Trek: The Next Generation. Does this make sense?
In this thought-provoking episode of Lifespan News, host Ryan O’Shea delves deep into the controversial topic of choosing when to die and the ethics surrounding medical interventions to prolong life. Using the lens of a Star Trek: The Next Generation episode and drawing parallels with Dr. Ezekiel Emanuel’s The Atlantic article, “Why I Hope to Die at 75″, Ryan confronts the moral and societal implications of setting an arbitrary age to stop seeking medical treatment. With advancements in rejuvenation biotechnologies, is it reasonable to maintain such views? As we push the boundaries of science and healthcare, when should we draw the line? Join Ryan as he navigates these complex questions, and remember to share your thoughts in the comments below. Don’t forget to subscribe for more!
This is a SURVEY result of Rapamycin users. Overall, it’s really good for you. It has not had a true trial as it is off-patent so it’s harder to get rich from it. Low dose use has minimal side effects if any at all. Many patients can get off-label prescription from their doctor.
Magnesium Breakthrough 10% Discount _https://bit.ly/3O5tPfu_ Code Modern10 This video brought to you by BiOptimizers. Here Prof Kaeberlein provides some updates on rapamycin, in particular the results from the survey based trial that his team ran and thoughts on next steps for the supplement.
Dr. Kaeberlein’s research interests are focused on biological mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life. He has published more than 200 scientific papers, has been recognized by several prestigious awards, and has Fellow status in the American Association for the Advancement of Science (AAAS), the American Aging Association, and the Gerontological Society of America (GSA). Dr. Kaeberlein is currently the CEO of the American Aging Association and has served on the Board of Directors for the Federation of American Societies for Experimental Biology (FASEB), AGE, and GSA. Dr. Kaeberlein is the founding Director of the UW Healthy Aging and Longevity Research Institute, the Director of the UW Nathan Shock Center of Excellence in the Basic Biology of Aging, Director of the Biological Mechanisms of Healthy Aging Training Program, and founder and co-Director of the Dog Aging Project.
DISCLOSURE: Longevity. Technology (a brand of First Longevity Limited) has been contracted by the company featured in this article to support its current funding round. Qualifying investors can find out more via the Longevity. Technology investor portal.
This week’s Longevity Summit Dublin is in full swing, bringing together experts from around the world, fostering collaboration and knowledge exchange in the pursuit of solutions to extend human healthspan. One of the speakers during today’s sessions was Stanford professor and surgeon, Dr Vinit Mahajan, who is also Chief Medical Advisor for longevity biotech startup Mitrix Bio.
In his address to summit delegates in Dublin, Mahajan presented the company’s fascinating preclinical technology: bioreactor-grown mitochondria designed to be transplanted into the human body to regenerate organs, reverse age-related disease, and support other longevity therapies.
Researchers have determined a new feature of how the natural ends of our chromosomes are protected from harmful outcomes.
In a new study, University of Michigan researchers looked at how the DNA damage recognition process seems to know the difference between harmful DNA breaks that need repair versus the natural ends of chromosomes, called telomeres, that need to be left alone.
“If possible, you repair it, and if you can’t repair it, then the cell dies. You don’t want to keep dividing with broken DNA. That’s what happens in a normal cell, and that’s a good thing,” said Jayakrishnan Nandakumar, a professor of molecular, cellular and developmental biology.
Researchers publishing in Biogerontology have tested multiple biomarkers in an effort to use them as proxies for aging, and some of their findings were surprising. A simple study with direct […].
