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Immunotherapy is a type of cancer treatment that stimulates a patient’s immune system to attack tumours.

While promising, its effectiveness varies among patients.

The new VUB technology helps identify in advance which patients are likely to benefit from this treatment.

The study introduces an innovative tracer targeting CD163, a molecular receptor on tumour-associated macrophages—immune cells that support tumour growth and protection.

Commonwealth Fusion Systems, a startup that was spun out of a project at the Massachusetts Institute of Technology’s research labs, announced plans this week to break ground on what it calls “the world’s first grid-scale fusion power plant.” The plant which is expected to come online sometime in the early 2030s, according to the company, will be built in Chesterfield County, Virginia.

The plan is certainly an ambitious one, starting with how the energy will be generated. Nuclear fusion is a notoriously difficult process that involves fusing together two light atomic nuclei into a single heavier one, resulting in the release of a massive amount of energy—it’s estimated to produce four times as much energy as nuclear fission reactions. The reaction that nuclear fusion generates is the same kind of reaction that powers the sun.

It’s not hard to imagine why one would want to be able to harness the energy of the sun. It is hard to actually, ya know, do that, though. To date, nuclear fusion has proven elusive—at least in a way that would produce usable energy. In 2022, scientists at Lawrence Livermore National Laboratory in California reached nuclear fusion “ignition” for the first time, meaning they successfully produced an excess of energy from the reactions. Prior to that breakthrough, which has since been replicated, it took more energy to produce the reaction than energy that came from it.

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world every year.

The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that’s prevented drugmakers from successfully using azole antifungal drugs to treat , or VL.

About 30 years ago, scientists discovered the two species of single-cell parasites that cause VL, Leishmania donovani and Leishmania infantum, made the same lipid sterol, called ergosterol, as fungi proven susceptible to azoles antifungals. These azoles antifungals target a crucial enzyme for sterol biosynthesis, called CYP51.

Mechanical crystals, also known as phononic crystals, are materials that can control the propagation of vibrations or sound waves, just like photonic crystals control the flow of light. The introduction of defects in these crystals (i.e., intentional disruptions in their periodic structure) can give rise to mechanical modes within the band gap, enabling the confinement of mechanical waves to smaller regions or the materials—a feature that could be leveraged to create new technologies.

Researchers at McGill University recently realized a new mechanical crystal with an optically programmable defect mode. Their paper, published in Physical Review Letters, introduces a new approach to dynamically reprogram mechanical systems, which entails the use of an optical spring to transfer a mechanical mode into a crystal’s band gap.

“Some time ago, our group was thinking a lot about using an optical spring to partially levitate structures and improve their performance,” Jack C. Sankey, principal investigator and co-author of the paper, told Phys.org. “At the same time, we were watching the amazing breakthroughs in our field with mechanical devices that used the band gap of a phononic crystal to insulate mechanical systems from the noisy environment.”

A groundbreaking advancement in technology is paving the way for mobile phones and other electronic devices to recharge simply by being kept in a pocket. This innovative system enables wireless charging throughout three-dimensional (3D) spaces, encompassing walls, floors, and air.

On December 12, Professor Franklin Bien and his research team in the Department of Electrical Engineering at UNIST announced the creation of a revolutionary electric resonance-based (ERWPT) system, marking a significant milestone in the field. This modern technology allows devices to charge virtually anywhere within a 3D environment, addressing the longstanding challenges associated with traditional magnetic resonance wireless power transfer (MRWPT) and offering a robust solution that enables efficient power transmission without the constraints of precise device positioning.

The paper is published in the journal Advanced Science.

Scientists at Neuro-Electronics Research Flanders (NERF), under the direction of Prof. Vincent Bonin, have released two innovative studies that provide fresh perspectives on the processing and distribution of visual information in the brain. These studies contest conventional beliefs regarding the straightforwardness of visual processing, instead emphasizing the intricate and adaptable nature of how the brain understands sensory information.

Read Full Story.

Scientists are developing nuclear clocks using thin films of thorium tetrafluoride, which could revolutionize precision timekeeping by being less radioactive and more cost-effective than previous models.

This new technology, pioneered by a collaborative research team, enables more accessible and scalable nuclear clocks that may soon move beyond laboratory settings into practical applications like telecommunications and navigation.

Breakthrough in Nuclear Clock Technology.