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Category: health – Page 407

More evidence to support that excess fat ages the body and is linked with inflammation and senescent cells.

Excess visceral fat tissue is very bad for long-term health. Being obese is by some measures as harmful as a smoking habit when it comes to remaining life expectancy. Even modest amounts of excess weight have a measurable negative impact on the future trajectory of health and longevity. There is an enormous mountain of data to support these points, ranging from large human studies to simple but compelling experiments in which the surgical removal of fat from mice leads to extended life spans. Unfortunately we evolved in an environment of scarcity and so find it a challenge to stay slim in an environment of plenty; this is a high class problem to have in exchange for an end to unavoidable famine and malnutrition, but a problem nonetheless.

One of the contributing causes of degenerative aging is the growing presence of senescent cells in tissues. While investigating the effects of changes in the amount of fat tissue in mice, researchers here find evidence to suggest that some portion of the damage done by fat tissue occurs because it hosts many more senescent cells than would otherwise be present in the body. These cells produce a mix of inflammatory signals, and may well be a sizable cause of the well-known link between visceral fat and increased inflammation. Chronic inflammation alone drives a faster progression of most of the common fatal age-related conditions, and that is without considering all of the other damage done due to the signaling produced by senescent cells.

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Philadelphia, PA, USA / Moscow, Russia — Bioquark, Inc., (http://www.bioquark.com) a life sciences company focused on the development of novel bio-products for regeneration, disease reversion, and healthy aging, announced the commercial approval of naturally derived Bioquantine food ingredients in the Eurasian Customs Union (formerly known as the Customs Union of Belarus, Kazakhstan, and Russia). Moscow based, Lakmus LLC, a diversified investment company with business interests in pharmacies, restaurants, and real estate, collaborated with Bioquark Inc. on the regulatory approvals.

green-cell

“We are very excited about this successful regulatory approval,” said Ira S. Pastor, CEO, Bioquark Inc. “The commercialization of Bioquantine food ingredients, including functional foods, drinks, and dietary supplements, represents another important step in our continued evolution as a company focused on a broad range of products and services in the regenerative healthcare space.”

Throughout the 20th century, natural products formed the basis for a majority of all pharmaceuticals, biologics, and consumer healthcare products used by patients around the globe, generating trillions of dollars of wealth. However, many scientists believe we have only touched the surface with what the natural world, and its range of organisms, which from a health and wellness perspective are much further advanced than human beings, has to teach us.

gene-sequencing

The integration of a complex set of newer research disciplines, including interkingdom signaling, semiochemical communication, and evolutionary biology, as well as significant recent activity in the areas of the microbiome and virome, are highlighting a myriad of new ways that non-human bio-products can affect the human genome for positive transitions in health and wellness dynamics.

“Bioquark has spent several years studying the natural ability of many species to turn back biological time in order to maintain health, fitness, and survival,” said Dr. Sergei Paylian, Founder, CSO, and President, Bioquark Inc. “This Eurasian initiative is one more step in the path in allowing humans to recapture these capabilities to effectively counter our unfortunate progression into aging, disease and degeneration.”

bqaproduction

About Bioquark, Inc.

Bioquark Inc. is focused on the development of natural biologic based products, services, and technologies, with the goal of curing a wide range of diseases, as well as effecting complex regeneration. Bioquark is developing both biological pharmaceutical candidates, as well as products for the global consumer health and wellness market segments.

Link to Press — http://www.prweb.com/releases/2017/01/prweb13955162.htm

In Brief

  • Microsoft is partnering with a prestigious eye hospital in India to help perfect AI powered computer diagnostics to the field of ophthalmology.
  • Artificial intelligence is continually making great strides to integrate more in various healthcare settings, hopefully increasing the quality and availability of patient care.

According to the World Health Organization, an estimated 285 million people are visually impaired, with 39 million living with blindness and the other 246 million having low vision.

In a world of modern technological advancements, visual impairment has been the subject of much medical research. Perhaps the most notable among these are those that use artificial intelligence (AI), specifically through machine learning. Google’s DeepMind has been working with the UK’s National Health Service to do ophthalmology research.

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The incidence of thyroid cancer has tripled in the past three decades, yet the reason for this is not clear.

Dr. David Goldenberg, chief of otolaryngology and head and neck surgery at Penn State Health Milton S. Hershey Medical Center, notes the diagnostic tools are better, but he can’t get behind recent talk of over-diagnosis as the sole cause for the increase.

“The press that has been given to this is an oversimplification,” Goldenberg said. “What we should be concentrating on is not only why we are discovering more of it, but also which of these newly discovered thyroid cancers are the ones that will kill someone.”

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Struggling with your diet? Your microbiota could be to blame.

Your microbiota may not be on your side as you try improving your diet this New Year’s. In a study published December 29 in Cell Host & Microbe, researchers explore why mice that switch from an unrestricted American diet to a healthy, calorie-restricted, plant-based diet don’t have an immediate response to their new program. They found that certain human gut bacteria need to be lost for a diet plan to be successful.

“If we are to prescribe a to improve someone’s health, it’s important that we understand what help control those beneficial effects,” says Jeffrey Gordon, Director of the Center for Genome Sciences and Systems Biology at Washington University in St. Louis and senior author of the paper. “And we’ve found a way to mine the gut microbial communities of different humans to identify the organisms that help promote the effects of a particular diet in ways that might be beneficial.”

In order to study how human dietary practices influence the and how a microbiota conditioned with one dietary lifestyle responds to a new prescribed diet, Gordon and his collaborators first took fecal samples from people who followed a calorie-restricted, plant-rich diet and samples from people who followed a typical, unrestricted American diet. The researchers found that people who followed the restricted, plant-rich diet had a more diverse microbiota.

Continue reading “Your microbiota’s previous dining experiences may make new diets less effective” | >

Nice.

Stem cell treatments involve some serious health risks for the patients and are very expensive. A new alternative developed for patients with health problems may be a game-changer as a team of researchers has developed synthetic stem cells, which prove to be as efficient as the regular ones. ( NC State University )

A team of researchers made a significant breakthrough which will help patients with heart problems all over the world. The scientists managed to create synthetic stem cells, which can help the heart tissue regenerate just as well as normal stem cells, while also avoiding the complications associated with them.

Promising Results

Continue reading “Synthetic Stem Cells Found Comparable To Natural Stem Cells In Therapeutic Benefits But With Reduced Risks” | >

(Photo courtesy of Clarius Mobile Health)

The ultrasound market currently stands as a $6 billion global industry.

Contrary to popular perception, the use of ultrasounds for women’s health and pregnancy follow-ups only represents less than 20% of the overall use for healthcare. For example, a diagnostic ultrasound is routinely used to diagnose an assortment of healthcare conditions such as cancer, gall stones, and cardiovascular diseases.

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Time to work off that Chritmas Turkey bigsmile

Making muscles burn more fat and less glucose can increase exercise endurance, but could simultaneously cause diabetes, says a team of scientists from Baylor College of Medicine and other institutions.

Mouse muscles use (carbohydrate) as fuel when the animals are awake and active and switch to fat (lipid) when they are asleep. The team discovered that disrupting this natural cycle may lead to diabetes but, surprisingly, can also enhance exercise endurance. The switch is controlled by a molecule called histone deacetylase 3, or HDAC3. This finding opens the possibility of selecting the right time to exercise for losing body fat but also raises the concern of using HDAC inhibitors as doping drugs for endurance exercise. The study appears in Nature Medicine.

“How the uses glucose is regulated by its internal that anticipates the level of its activity during the day and at night,” said senior author Dr. Zheng Sun, assistant professor of medicine—diabetes, endocrinology and metabolism, and of molecular and cellular biology at Baylor. “The circadian clock works by turning certain genes on and off as the 24-hour cycle progresses. HDAC3 is a key connection between the circadian clock and gene expression. Our previous work showed that HDAC3 helps the liver alternate between producing glucose and producing lipid. In this work, we studied how HDAC3 controls the use of different fuels in .”

Continue reading “Losing body fat could be facilitated” | >