Lifeboat Foundation

Being able to see, move, and exercise independently is something most of us take for granted. [Thomas Panek] was an avid runner before losing his sight due to a genetic condition, and had to rely on other humans and guide dogs to run again. After challenging attendants at a Google hackathon, Project Guideline was established to give blind runners (or walkers) independence from a cane, dog or another human, while exercising outdoors. Using a smartphone with line following AI software, and bone conduction headphones, users can be guided along a path with a line painted on it. You need to watch the video below to get a taste of just how incredible it is for the users.

Getting a wheeled robot to follow a line is relatively simple, but a running human is by no means a stable sensor platform. At the previously mentioned hackathon, developers put together a rough proof of concept with a smartphone, using its camera to recognize a painted line on the ground and provide left/right audio cues. As the project developed, the smartphone was attached to a waist belt and bone conduction headphones were used, which don’t affect audio situational awareness as much as normal headphones.

The shaking and side to side movement of running, and varying light conditions and visual obstructions in the outdoors made the problem more difficult to solve, but within a year the developers had completed successful running tests with [Thomas] on a well-lit indoor track and an outdoor pedestrian path with a temporary line. For the first time in 25 years, [Thomas] was able to run independently.

From the COVID-19 vaccine to advances in machine learning, AI, improved W-Fi and 5G, and telemedicine, experts expect a move to “patient-centric” health next year.

COVID-19 accomplished what entrepreneurs, doctors, and activists couldn’t: Designing a healthcare system that works for patients instead of providers and health insurance companies.

The industry promised to be “patient-centered” for the last decade but only the harsh demands of COVID-19 have made this a reality. As Ian McCrae, CEO of Orion Health, described it, COVID-19 is ushering in the long-overdue transformation of the healthcare system and, finally, a move to “patient-centric” health.

Drexel University researchers are one step closer to offering a new treatment for the millions of patients who suffer from slow-healing, chronic wounds. The battery-powered applicator — as small and light as a watch — is the first portable and potentially wearable device to heal wounds with low-frequency ultrasound.

The National Institutes of Health (NIH) has awarded the research team an estimated $3 million to test the therapy on 120 patients over the next five years. By using diagnostic monitoring of blood flow in the wound tissue, the clinical trial will also determine how nutrition and inflammation impact wound closure, making treatment customization a possibility.

Continue reading “NIH Funds Clinical Trial to Test Device That Heals Wounds With Ultrasound” »

Today we’re joined by Melodie Yashar — Designer, Researcher, Technologist, co-founder of the firm Space Exploration Architecture (SEArch+), Senior Research Associate with San Jose State University Research Foundation at NASA Ames Research Center, and an Associate Researcher within the UC Davis Center for Human/Robotics/Vehicle Integration and Performance (HRVIP). She also teaches undergraduate and graduate design at Art Center College of Design and is a 2019–2020 Future Space Leaders Fellow.

Melodie’s current work focuses on the relationship of advanced software & hardware systems for spaceflight and maintains ongoing research interests in the design of augmented environments, human-machine interaction, human performance studies, and space technology development.

Continue reading “Melodie Yashar — Co-Founder of Space Exploration Architecture (SEArch+)” »

Health experts have speculative guesses but no answers for what’s causing it.

Coronaviruses are enveloped, positive-stranded RNA viruses with a genome of approximately 30 kb. Based on genetic similarities, coronaviruses are classified into three groups. Two group 2 coronaviruses, human coronavirus OC43 (HCoV-OC43) and bovine coronavirus (BCoV), show remarkable antigenic and genetic similarities. In this study, we report the first complete genome sequence (30,738 nucleotides) of the prototype HCoV-OC43 strain (ATCC VR759). Complete genome and open reading frame (ORF) analyses were performed in comparison to the BCoV genome. In the region between the spike and membrane protein genes, a 290-nucleotide deletion is present, corresponding to the absence of BCoV ORFs ns4.9 and ns4.8. Nucleotide and amino acid similarity percentages were determined for the major HCoV-OC43 ORFs and for those of other group 2 coronaviruses. The highest degree of similarity is demonstrated between HCoV-OC43 and BCoV in all ORFs with the exception of the E gene. Molecular clock analysis of the spike gene sequences of BCoV and HCoV-OC43 suggests a relatively recent zoonotic transmission event and dates their most recent common ancestor to around 1890. An evolutionary rate in the order of 4 × 10⁻⁴ nucleotide changes per site per year was estimated. This is the first animal-human zoonotic pair of coronaviruses that can be analyzed in order to gain insights into the processes of adaptation of a nonhuman coronavirus to a human host, which is important for understanding the interspecies transmission events that led to the origin of the severe acute respiratory syndrome outbreak.

Coronaviruses are large (120- to 160-nm), roughly spherical particles with a linear, nonsegmented, capped, and polyadenylated positive-sense single-stranded RNA genome that is encapsidated in a helical nucleocapsid. The envelope is derived from intracellular membranes and contains a characteristic crown of widely spaced club-shaped spikes that are 12 to 24 nm long. The genus Coronavirus (International Committee on the Taxonomy of Viruses database [ICTVdb], virus code 03.019.0.1) belongs to the family Coronaviridae in the order Nidovirales (7, 8).

Before the 2002-to-2003 severe acute respiratory syndrome (SARS) epidemic, coronaviruses were somewhat neglected in human medicine, but they have always been of considerable importance in animal health. Coronaviruses infect a variety of livestock, poultry, and companion animals, in whom they can cause serious and often fatal respiratory, enteric, cardiovascular, and neurologic diseases (25). Most of our understanding about the molecular pathogenic properties of coronaviruses has been achieved by the veterinary virology community.

Exciting momentum!! — Home Depot Founder, Bernie Marcus (age 91), and the Adolph Coors Foundation (beer family), putting millions of $$$ into comprehensive integrative health and wellness — Good to see the trend!!

The Marcus Institute of Integrative Health was established in Philadelphia in 2017 by Thomas Jefferson University and Jefferson Health, and a multi-million $$$ grant from the Marcus Foundation (headed by it’s Chairman, Bernie Marcus, Co-Founder of The Home Depot) to expand the research, education and clinical care profile of Jefferson’s integrative medicine program, and to set the international standard of excellence in evidence-based, patient-centered integrative care.

Continue reading “Dr Daniel Monti — CEO & Founding Director, Marcus Institute of Integrative Health — Jefferson Health” »

The most expedient way to produce the algorithms you need for a new class of computer that works like the brain, its engineers are discovering, is through a Darwinian exercise in natural selection.

After controlling for various factors — such as participants’ age, sex, smoking status and activity level — the researchers found that taking glucosamine/chondroitin every day for a year or longer was associated with a 39 percent reduction in all-cause mortality.

It was also linked to a 65 percent reduction in cardiovascular-related deaths. That’s a category that includes deaths from stroke, coronary artery disease and heart disease, the United States’ biggest killer.” “He explains that because this is an epidemiological study — rather than a clinical trial — it doesn’t offer definitive proof that glucosamine/chondroitin makes death less likely. But he does call the results “encouraging.””.

Glucosamine supplements may reduce overall mortality about as well as regular exercise does, according to a new epidemiological study from West Virginia University.

“Does this mean that if you get off work at five o’clock one day, you should just skip the gym, take a glucosamine pill and go home instead?” said Dana King, professor and chair of the Department of Family Medicine, who led the study. “That’s not what we suggest. Keep exercising, but the thought that taking a pill would also be beneficial is intriguing.”

Continue reading “Glucosamine may reduce overall death rates as effectively as regular exercise, study suggests” »