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Dr. Diane DiEuliis — NDU — Preparing National Security Leaders For The Next Generation Of Threats

Episode Disclaimer — The views presented in this episode are those of the speaker and do not necessarily represent the views of the United States Department of Defense (DoD) or its components.

Dr. Diane DiEuliis, Ph.D. is a Distinguished Research Fellow at National Defense University (NDU — https://www.ndu.edu/), an institution of higher education, funded by the United States Department of Defense, aimed at facilitating high-level education, training, and professional development of national security leaders. Her research areas focus on emerging biological technologies, biodefense, and preparedness for biothreats. Specific topic areas under this broad research portfolio include dual-use life sciences research, synthetic biology, the U.S. bioeconomy, disaster recovery, and behavioral, cognitive, and social science as it relates to important aspects of deterrence. Dr. DiEuliis currently has several research grants in progress, and teaches in foundational professional military education.

Prior to joining NDU, Dr. DiEuliis was Deputy Director for Policy, and served as Deputy Assistant Secretary for Policy and Planning in the Office of the Assistant Secretary for Preparedness and Response (ASPR), Department of Health and Human Services. She coordinated policy and research in support of domestic and international health emergencies, such as Hurricane Sandy, and Ebola outbreaks. She was responsible for implementation of the Pandemic All-Hazards Preparedness Act, the National Health Security Strategy, and supported the Public Health Emergency Medical Countermeasures Enterprise (PHEMCE).

From to 2007 to 2011, Dr. DiEuliis was the Assistant Director for Life Sciences and Behavioral and Social Sciences in the Office of Science and Technology Policy (OSTP) in the Executive Office of the President. During her tenure at the White House, she was responsible for developing policy in areas such as biosecurity and biodefense, synthetic biology, social and behavioral science, scientific collections, and biotechnology. Dr. DiEuliis also worked to help coordinate agency response to public health issues such as the H1N1 flu.

Prior to working at OSTP, Dr. DiEuliis was a program director at the National Institutes of Health (NIH), where she managed a diverse portfolio of neuroscience research in neurodegenerative diseases. She completed a fellowship at the University of Pennsylvania in the Center for Neurodegenerative Disease Research and completed her postdoctoral research in the NIH Intramural research program, where she focused on cellular and molecular neuroscience.

Dr. DiEuliis is a National Merit Scholar, and has a Ph.D. in biology from the University of Delaware in Newark, Delaware. She is the author of over 70 publications.

A new gene-editing system tackles complex diseases

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup. That small 0.4% accounts for any difference between one person and another. Specific combinations of mutations in those base pairs hold important clues about the causes of complex health issues, including heart disease and neurodegenerative diseases like schizophrenia.

Elon Musk debuts Starlink satellite internet service in Indonesia

Elon Musk traveled to Bali this weekend to officially launch Starlink, the SpaceX satellite internet service, in Indonesia this Sunday.

At a launch event with ministers in a health clinic in Indonesia, Musk stressed the significance of providing internet access to far-reaching corners of the vast archipelago, comprised of 17,000 islands across three time zones.

Vitamin D Alters Mouse Gut Bacteria to give Better Cancer Immunity

Researchers at the Francis Crick Institute, the National Cancer Institute (NCI) of the U.S. National Institutes of Health (NIH) and Aalborg University in Denmark have found that vitamin D encourages the growth of a type of gut bacteria in mice which improves immunity to cancer.

Reported today in Science, the researchers found that mice given a diet rich in vitamin D had better immune resistance to experimentally transplanted cancers and improved responses to immunotherapy treatment. This effect was also seen when gene editing was used to remove a protein that binds to vitamin D in the blood and keeps it away from tissues.

Surprisingly, the team found that vitamin D acts on epithelial cells in the intestine, which in turn increase the amount of a bacteria called Bacteroides fragilis. This microbe gave mice better immunity to cancer as the transplanted tumours didn’t grow as much, but the researchers are not yet sure how.

Spontaneous Persistent Inactivity — Scientists Discover New Type of Memory State

UCLA Health researchers have identified a process that memories while reducing metabolic costs, even during sleep. This efficient memory is found in a brain region essential for learning and memory, which is also where Alzheimer’s disease originates.

The discovery is published in the journal Nature Communications.

Does this sound familiar: You go to the kitchen to fetch something, but when you get there, you forget what you wanted. This is your working memory failing. Working memory is defined as remembering some information for a short period while you go about doing other things. We use working memory virtually all the time. Alzheimer’s and dementia patients have working memory deficits and it also shows up in mild cognitive impairment (MCI). Hence, considerable effort has been devoted to understanding the mechanisms by which the vast networks of neurons in the brain create working memory.

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