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Category: health – Page 473

A universal therapy that targets mis-folded proteins is a very significant step forward if clinical trials in humans translate from animals. Obviously there is more work to be done but it this is the kind of technology we need in order to intervene against biological aging.

It is not hard to see that a therapy like this followed up by another that regenerates the brain eg, the Conboy Lab work by promoting neurogenesis could be a way to repair and restore the brain to healthy function.

A drug that breaks up different types of brain plaque shows promising results in animals and could prevent Alzheimer’s and Parkinson’s disease.

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While exploring which biological processes might predict successful in centenarians, a team from Newcastle and Tokyo have identified two prominent factors that facilitate health longevity — low level inflammation and telomere length.

“Centenarians and supercentenarians are different — put simply, they age slower. They can ward off diseases for much longer than the general population.”

After measuring a number of health markers in 1,554 people including: those over 105, between 100 and 105 and a group near their 100th birthday along with their offspring, these two elements emerged as consistent longevity predictors.

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Leukocyte (white blood cell) telomere length in study participants up to 115 years of age. Statistical regression lines belonging to these groups are indicated by the same color as the data. (credit: Yasumichi Arai et al./EBioMedicine)

Scientists say they have cracked the secret of why some people live a healthy and physically independent life over the age of 100: keeping inflammation down and telomeres long.

Newcastle University’s Institute for Ageing in the U.K. and Keio University School of Medicine note that severe inflammation is part of many diseases in the old, such as diabetes or diseases attacking the bones or the body’s joints, and chronic inflammation can develop from any of them.

The study was published online in an open-access paper in EBioMedicine, a new open-access journal jointly supported by the journals Cell and Lancet.

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The Millennium Project released today its annual “2015–16 State of the Future” report, listing global trends on 28 indicators of progress and regress, new insights into 15 Global Challenges, and impacts of artificial intelligence, synthetic biology, nanotechnology and other advanced technologies on employment over the next 35 years.

“Another 2.3 billion people are expected to be added to the planet in just 35 years,” the report notes. “By 2050, new systems for food, water, energy, education, health, economics, and global governance will be needed to prevent massive and complex human and environmental disasters.”

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Once again telomeres are shown to be key players in aging.

The secret to living long, healthy lives and ageing beyond 100 has finally been cracked, according to a new study.

Scientists at Newcastle University say they have identified the key to longevity and good health amongst centenarians and how they pass that gift onto their offspring.

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Not long ago, schoolchildren chose what they wanted to be when they grew up, and later selected the best college they could gain admission to, spent years gaining proficiency in their fields, and joined a company that had a need for their skills. Careers lasted lifetimes.

Now, by my estimates, the half-life of a career is about 10 years. I expect that it will decrease, within a decade, to five years. Advancing technologies will cause so much disruption to almost every industry that entire professions will disappear. And then, in about 15–20 years from now, we will be facing a jobless future, in which most jobs are done by machines and the cost of basic necessities such as food, energy and health care is negligible — just as the costs of cellphone communications and information are today. We will be entering an era of abundance in which we no longer have to work to have our basic needs met. And we will gain the freedom to pursue creative endeavors and do the things that we really like.

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