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Archive for the ‘genetics’ category: Page 119

May 31, 2023

Brain Computer Interfaces in 2050: Top 10 Future Technologies

Posted by in categories: augmented reality, bioengineering, business, genetics, robotics/AI, transhumanism

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May 31, 2023

First-of-Its-Kind Gene Therapy Can Be Applied to Skin Instead of Injected

Posted by in categories: biotech/medical, genetics

The root cause is frustratingly simple: one gene mutation, which affects a critical protein that helps support skin integrity. The single genetic error makes the illness a perfect candidate for gene therapy. Yet with the skin already fragile, injections—a current standard for gene therapy—are hard to tolerate.

What about a genetic moisturizer instead?

This month, the FDA approved the first rub-on gene therapy. Similar to aloe vera for treating sunburns, the therapy comes in a gel that’s gently massaged onto blisters and wounds to help with healing. Dubbed Vyjuvek, it directly delivers healthy copies of the mutated gene onto damaged skin. An alternative version is configured into eye drops to reconstruct the eye’s delicate architecture to better support sight.

May 31, 2023

Chinese scientists say their new gene-editing tool is precise and safe

Posted by in categories: biotech/medical, genetics

‘Base editors’ fix specific sites in the genome without cutting the DNA double helix, according to team.

May 30, 2023

Unveiling a Genetic Breakthrough: Enhancing Cancer-Killing Cells and Extending Lifespan

Posted by in categories: biotech/medical, genetics, life extension

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In the pursuit of extending healthy human lifespans, scientists have achieved a remarkable breakthrough that marks a significant milestone in the field. Researchers from Taipei Medical University in Taiwan have uncovered a genetic modification in mice that can empower cancer-killing cells, increasing their effectiveness by two to seven times while extending their lifespan by up to 20 percent.

Building upon last year’s groundbreaking study, the scientists have now successfully replicated these extraordinary outcomes in ordinary mice through a single transplant of blood stem cells. The findings, published in the scientific journal Cold Spring Harbor Protocols, hold immense importance, according to Che-Kun James Shen, the lead researcher of the study. He believes that these findings could have profound implications for human health and anticipates that clinical trials could commence as early as the end of this year or next year.

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May 30, 2023

The Woman Who Doesn’t Feel Pain — New Study Reveals Her Unique Molecular Machinery

Posted by in categories: biotech/medical, genetics, nanotechnology

New research from UCL, investigating the biology of a rare genetic mutation that enables carrier Jo Cameron to live virtually without pain and fear while also healing quickly, discovered that the mutation in FAAH-OUT gene ‘turns down’ FAAH gene expression, affecting molecular pathways related to wound healing and mood, thereby offering potential new targets for drug discovery.

New research from University College London (UCL) has unraveled the biology behind a unique genetic mutation that results in its carrier experiencing minimal pain, enhanced healing, and lower levels of anxiety and fear.

Published in the journal Brain, the research is a follow-up to the team’s 2019 discovery of the FAAH-OUT gene and its rare mutations, which make Jo Cameron almost immune to pain, and devoid of fear and anxiety. The latest study elucidates how this mutation reduces the expression of the FAAH gene and impacts other molecular pathways associated with mood and wound healing. The insights garnered from these findings could potentially pave the way for novel drug targets and foster further research in these domains.

May 29, 2023

Hope for age-related hearing loss with novel gene therapy

Posted by in categories: biotech/medical, genetics, life extension

Age-related hearing loss impacts one in three adults between the ages of 64 and 75 in the US, and around half of these numbers are down to genes.

The extra kicker, though, is that because hearing involves a complex genetic toolkit, it also makes this kind of hearing loss incredibly difficult to treat.

A team of researchers has for the first time targeted age-related genetic hearing loss in a much older cohort of mice, which had a mutation of the human transmembrane serine protease 3 (TMPRSS3) gene that results in autosomal recessive deafness 8/10 (DFNB8/DFNB10).

May 29, 2023

A Mutation Turned Ants Into Parasites in One Generation

Posted by in category: genetics

A new genetics study of ant “social parasites” shows how complex sets of features can emerge rapidly and potentially split species.

May 29, 2023

We’re analysing DNA from ancient and modern humans to create a ‘family tree of everyone’

Posted by in categories: biotech/medical, evolution, genetics

How we’re linking together genetic material from thousands of people — modern and ancient — to trace our ancestors and the history of our evolution.

May 29, 2023

The DNA of Decision-Making

Posted by in categories: biotech/medical, food, genetics

Summary: A novel study uncovers a peculiar pattern of decision-making in mice, influenced by a specific gene named Arc.

While searching for food, mice repeatedly visited an empty location instead of staying at a site abundant in food. However, mice lacking the Arc gene demonstrated a more practical approach, sticking with the food-rich site, thereby consuming more calories overall.

This unique research potentially opens the door for a new field, ‘decision genetics’, investigating the genetic influence on decision-making, possibly even in humans.

May 28, 2023

Blood Test #3 in 2023: Supplements, Diet

Posted by in categories: biotech/medical, genetics

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