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Next Generation Cancer Therapy Reveals Major Opportunity

GTB-3550 is the company’s first TriKE® product candidate that was evaluated in Phase 1 clinical trials for the treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and other CD33+ hematopoietic malignancies. Phase 1 clinical trials were shown to be both safe and well-tolerated, as well as proving the molecule’s clinical concept and providing a framework for future product candidates.

GTB-3650 is a second-generation protein developed to treat AML and MDS. It has replaced GTB-3550 and utilizes camelid nanobody technology. GTB3650 has successfully completed pre-clinical trials and is in the good manufacturing process (GMP) stage, which is usually the last developmental milestone before progressing into phase 1 clinical trials.

Statins use linked to decline in osteoporotic fractures among elderly

Researchers have found in a new study that statin use was associated with significant reduction in the risk of osteoporotic fractures among general older population.

Research author Dr Seo said, “Statin users experienced a decline in risk of major osteoporotic fractures, hip fractures and vertebral fractures.”

The study has been published in Osteoporosis International entitled Age-and dose-dependent effect of statin use on the risk of osteoporotic fracture in older adults.

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