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Neuroprotective effects of Cratoxylum formosum (L.) leaf extract on β-amyloid-induced injury in human neuroblastoma SH-SY5Y cells

Palachai, N., Buranrat, B., Pariwatthanakun, C. et al. Neuroprotective effects of Cratoxylum formosu m (L.) leaf extract on β-amyloid-induced injury in human neuroblastoma SH-SY5Y cells. Sci Rep 15, 44,730 (2025). https://doi.org/10.1038/s41598-025-28739-3

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Legendary Doom developer John Carmack theorizes that the world’s tech could run on outdated hardware if it was properly optimized

Id Software co-founder and programmer John Carmack shared a theory that if „optimization was truly a priority… modern tech could run on outdated hardware.

Single enzyme streamlines production of all four RNA building blocks

A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been identified by researchers at the Institute of Science Tokyo. The study was published online in the journal Nature Communications.

By using polyphosphate as a phosphate donor, the enzyme efficiently converts inexpensive nucleotide precursors into the active forms required for RNA synthesis. Overall, the method dramatically simplifies the process of nucleotide production—offering a low-cost, efficient option for the in vitro synthesis of RNA.

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