Microsoft is investigating an ongoing outage that is blocking admins worldwide from accessing the Exchange Admin Center (EAC).
The company tagged this ongoing issue as a critical service issue tracked under EX1051697 on the Microsoft 365 Admin Center, and it says that “at this time appears to be a global issue.”
Since the outage started two hours ago, affected IT administrators have reported seeing “HTTP Error 500” errors when attempting to log into the Exchange admin center portal.
Critical Gladinet CentreStack flaw CVE-2025–30406 actively exploited in March 2025 enables remote code execution.
Microsoft patched 126 vulnerabilities including actively exploited CVE-2025–29824, leaving Windows 10 users exposed.
A vivid digital reconstruction has brought to life the face of a Mycenaean woman who lived over 3,500 years ago, offering an unusually poignant glimpse into the world of ancient Greece, from long before the time of Homer or the Trojan War.
This ambitious project was launched at the initiative of Dr. Emily Hauser, a historian and lecturer in Classical Studies at the University of Exeter. The final image, she said, was both “incredibly exciting” and “unexpectedly modern.”
“For the first time, we are looking into the face of a woman from a kingdom associated with Helen of Troy —Helen’s sister, Clytemnestra, was queen of Mycenae in legend—and from where the poet imagined the Greeks of the Trojan War setting out,” Dr. Hauser explained in an interview published in the Daily Mail.
Exotic locales abound in April’s new SF novels: Wakanda, the Klingon Empire, and… the Huntington Library in near-future Los Angeles County?
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A protein platform rapidly develops peptide-focused major histocompatibility complex class I binders with high specificity.
Van Andel Institute scientists and collaborators have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells.
These sugars, called glycans, help cells recognize and communicate with each other. They also act as a cellular “signature,” with each subtype of pancreatic cancer cell possessing a different composition of glycans.
The new method, multiplexed glycan immunofluorescence, combines specialized software and imaging techniques to pinpoint the exact mix of pancreatic cancer cells that comprise tumors. In the future, this information may aid in earlier, more precise diagnosis.
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Although ADHD was originally considered to be a disorder of childhood, it has been clear for years that it also impacts adults. At least 60% of children diagnosed with ADHD struggle with symptoms into adulthood and the estimated prevalence of ADHD in adults is between 4 and 5%. As with children and teens, medication treatment is…
