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A new study shows that the cerebral cortex predicts the future by detecting novel stimuli and forming short-term memory traces called “echoes.” This mechanism, confirmed through neural network modeling, plays a key role in perception and learning.

The cerebral cortex is the largest part of a mammal’s brain and plays a crucial role in various cognitive functions. In humans, it is responsible for perception, thought, memory storage, and decision-making. One hypothesis suggests that the cortex’s primary function is to predict future events by processing new sensory information and comparing it to prior expectations.

A newly published study in Neuron provides significant evidence supporting this hypothesis. The research, led by Yuriy Shymkiv, a postdoctoral fellow in Professor Rafael Yuste’s lab, marks a major step forward in understanding the predictive role of the cortex.

Neuronal dendrites must relay synaptic inputs over long distances, but the mechanisms by which activity-evoked intracellular signals propagate over macroscopic distances remain unclear. Here, we discovered a system of periodically arranged endoplasmic reticulum-plasma membrane (ER-PM) junctions tiling the plasma membrane of dendrites at ∼1 μm intervals, interlinked by a meshwork of ER tubules patterned in a ladder-like array. Populated with Junctophilin-linked plasma membrane voltage-gated Ca2+ channels and ER Ca2+-release channels (ryanodine receptors), ER-PM junctions are hubs for ER-PM crosstalk, fine-tuning of Ca2+ homeostasis, and local activation of the Ca2+/calmodulin-dependent protein kinase II.

Beyond the general recommendation to consume yogurt, this research raises questions about which products might offer the most benefit. Not all yogurts contain the same bacterial strains or concentrations. While many products include Bifidobacterium, the amounts can vary significantly. Future research may help determine whether certain formulations provide better protection against colorectal cancer.

Different subtypes of colorectal cancer may respond differently to preventive measures, suggesting that a one-size-fits-all approach to prevention might not be optimal. This understanding could eventually lead to more personalized prevention strategies based on individual risk factors and gut bacterial composition.

Have you ever felt like the world around you is losing its grip on reality? What if entire societies could descend into madness without realizing it?

In this eye-opening video, we explore the concept of mass psychosis—a phenomenon that has shaped history through witch hunts, oppressive regimes, and ideological purges. Guided by insights from great thinkers like Carl Jung, Hannah Arendt, and Joost Meerloo, we unravel the hidden mechanisms that manipulate public perception, erode critical thinking, and lead populations into collective delusion.

🔎 What You’ll Discover:
✅ How fear is weaponized to control societies.
✅ The role of propaganda in shaping public opinion.
✅ The dangers of blind conformity and obedience.
✅ How to protect your mind from mass manipulation.

Mass psychosis does not last forever—eventually, reality breaks through. But will we wake up before it’s too late? Watch now to uncover the truth and learn how to resist the forces that seek to control you.

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👍 Like, Comment, and Share to help others wake up!

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Researchers, led by the University of Melbourne’s Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), in collaboration with Pfizer, have discovered new insights into possible future treatments for breast cancer.

A new dual-target drug that has been shown to supercharge cancer-fighting immune cells in mice may support a new treatment approach for patients, potentially paving the way for improved outcomes in breast cancer care.

Breast cancer is the fifth most common cause of cancer death in Australia, with more than 20,000 Australians diagnosed per year. Over 1,000 of those diagnosed are young Australian women under 40. There is an urgent need to discover more effective treatments for breast cancer.