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Multitissue single-cell analysis reveals differential cellular and molecular sensitivity between fructose and high-fat high-sucrose diets

Chen et al. compared scRNA-seq profiles of four tissues in metabolic syndrome (MetS) models induced by fructose or high-fat high-sucrose diets, revealing differential tissue, cellular, and molecular vulnerability between diets. Regulatory genes and pathways were identified, and networks were rewired in MetS. mt-Rnr2 was validated as a key regulator.

Scientists Detect Unusual Airborne Toxin in the United States for the First Time

University of Colorado Boulder researchers made the first-ever airborne detection of Medium Chain Chlorinated Paraffins (MCCPs) in the Western Hemisphere. Sometimes, scientific research feels a lot like solving a mystery. Scientists head into the field with a clear goal and a solid hypothesis, bu

Microsoft shares temp fix for Outlook crashes when opening emails

Microsoft has shared a workaround for a known issue that causes the classic Outlook email client to crash when opening or starting a new message.

These problems affect users in the Monthly Enterprise Channel who updated Outlook for Microsoft 365 earlier this month, starting with Version 2,504 (Build 18730.20122).

“When you open or start a new email, classic Outlook crashes. This issue occurs because Outlook cannot open the Forms Library,” the Outlook team says in a support document published on Friday.

Antarctica has a huge, completely hidden mountain range. New data reveals its birth over 500 million years ago

Have you ever imagined what Antarctica looks like beneath its thick blanket of ice? Hidden below are rugged mountains, valleys, hills and plains.

Some peaks, like the towering Transantarctic Mountains, rise above the ice. But others, like the mysterious and ancient Gamburtsev Subglacial Mountains in the middle of East Antarctica, are completely buried.

The Gamburtsev Mountains are similar in scale and shape to the European Alps. But we can’t see them because the high alpine peaks and deep glacial valleys are entombed beneath kilometres of ice.