Watch out, George Lucas, there’s a new attack of the clones, and these ones are furry.
Japanese researchers have created a potentially endless line of mice cloned from other cloned mice. They used the same technique that created Dolly the sheep to produce 581 mice from an original donor mouse through 25 rounds of cloning, the scientists report in the March 7 issue of the journal Cell Stem Cell.
“This technique could be very useful for the large-scale production of superior-quality animals, for farming or conservation purposes,” study leader Teruhiko Wakayama of the RIKEN Center for Developmental Biology in Kobe, Japan, said in a statement.
Biotin is also known as vitamin H, named for the German words “Haar” and “Haut,” which mean hair and skin. This was due to the fact that even slight deficiencies cause hair thinning, skin rash or brittle fingernails. New research, just published in PNAS, now shows that some forms of severe neurodegeneration, like the frontotemporal dementia seen in Alzheimer’s and Parkinson’s, can directly result from lack of sufficient biotin.
The authors discovered this by looking at fruit flies with dementia. Now, before anyone chuckles, fruit flies actually make a nice model of Alzheimer’s or other diseases when they are given the right genes. Human versions of defective MAPT (tau) genes cause these flies to develop tauopathies that resemble those that occur in our own brains. To delve deeper into the neurotoxicity of tau, they looked at over 7000 fly genes in a forward genetic screen before zeroing in on one significantly modified toxicity of the tauR406W mutant. This gene, Btnd, encodes the biotinidase enzyme that extracts biotin from food sources or recycles it from used enzymes.
Over the past few years, computer scientists have developed increasingly advanced and sophisticated artificial intelligence (AI) tools, which can tackle a wide variety of tasks. This includes generative adversarial networks (GANs), machine-learning models that can learn to generate new data, including text, audio files or images. Some of these models can also be tailored for creative purposes, for instance, to create unique drawings, songs or poems.
Researchers at Tongji University in Shanghai in China and the University of Delaware in the US have recently created a GAN-based model that can generate abstract artworks inspired by Chinese calligraphy. The term Chinese calligraphy refers to the artistic form in which Chinese characters were traditionally written.
“In 2019, we collaborated with a restaurant based in Shanghai to showcase some AI technologies for better customer engagement and experience,” Professor Harry Jiannan Wang, one of the researchers who carried out the study, told TechXplore. “We then had the idea to use AI technologies to generate personalized abstract art based on the dishes customers order and present the artwork to entertain customers while they wait for their meals to be served.”
Have you been sleeping worse since the pandemic came round? If so, do not despair, you are not alone, studies have found that even amongst those who previously had no problems, there were issues. Now there are many reasons why this might be so, from added stress and uncertainty, to less physical exertion during the day and much more… But, one factor that can play a huge role is your diet. I am sure you know about fast and slow carbs, and I am sure some of you try your hardest to avoid them at all costs…not me though, I am a carb fan lol. But anyway, carbs can actually help you sleep when paired with the right foods because of the way they create competition between amino acids for absorption into muscles, when stimulated by glucose, but on the negative side, quick, or beige, carbs can cause waking during the night, as the blood sugar is not as stable. If you want to find out more, in a bit more depth, along with all the studies I have brought together, then check out this video, all links are in its description. Sleep well wink
In Carbs Sleep Problems — How Nutrition Affects Your Sleep Quality, I look at just that, the importance of the reciprocal link between diet and sleep.
What do you think, leave a comment below with your thoughts… If you want to try Melatonin to aid your sleep, or any other of their products, I have arranged a discount for my friends and viewers at Do Not Age, the highest quality, the lowest prices and the best customer service, all in one place. Just use the code MTB when checking out. https://donotage.org And if you want to watch another video on the importance of sleep then try this — https://youtu.be/iByq-KYVt3I To follow up on the studies I mentioned follow these links — Poor sleep and diet linked (epidemiological study) https://www.ahajournals.org/doi/10.11… of diet on sleep quality https://academic.oup.com/advances/art… Mediterranean diet pattern and sleep duration and insomnia symptoms in the Multi-Ethnic Study of Atherosclerosis https://pubmed.ncbi.nlm.nih.gov/30137… Fiber and Saturated Fat Are Associated with Sleep Arousals and Slow Wave Sleep https://pubmed.ncbi.nlm.nih.gov/26156… Nutritional effects on sleep https://pubmed.ncbi.nlm.nih.gov/21816… Short sleep duration, glucose dysregulation and hormonal regulation of appetite in men and women https://pubmed.ncbi.nlm.nih.gov/23115… Sleep extension is a feasible lifestyle intervention in free-living adults who are habitually short sleepers: a potential strategy for decreasing intake of free sugars? A randomized controlled pilot study https://pubmed.ncbi.nlm.nih.gov/29381…
Executive director & co-founder of kiss the ground, and producer of kiss the ground the movie, discussing regenerative agriculture for planetary regeneration.
Ryland Engelhart, is Executive Director & Co-Founder of Kiss The Ground (https://kisstheground.com/), a non-profit organization dedicated to planetary regeneration, and is the producer of Kiss The Ground, the Movie, recently released on Netflix.
Mr. Engelhart has spent the last 15 years as an entrepreneur working in hospitality and building a family business of organic, plant-based restaurants called Cafe Gratitude and Gracias Madre, located in Southern California.
After the tweet by David Sinclair just recently regarding a study looking at dietary restriction and the circadian clock, and the way it may impact longevity and health, I decided to have a bit of a deeper look.
Join me as I dive a little deeper, and don’t forget to subscribe to the channel to keep up with all the latest releases.
I am looking at the recent study, highlighted in a tweet by David Sinclair.
Brown fat is that magical tissue that you would want more of. Unlike white fat, which stores calories, brown fat burns energy and scientists hope it may hold the key to new obesity treatments. But it has long been unclear whether people with ample brown fat truly enjoy better health. For one thing, it has been hard to even identify such individuals since brown fat is hidden deep inside the body.
Now, a new study in Nature Medicine offers strong evidence: among over 52000 participants, those who had detectable brown fat were less likely than their peers to suffer cardiac and metabolic conditions ranging from type 2 diabetes to coronary artery disease, which is the leading cause of death in the United States.
The study, by far the largest of its kind in humans, confirms and expands the health benefits of brown fat suggested by previous studies. “For the first time, it reveals a link to lower risk of certain conditions,” says Paul Cohen, the Albert Resnick, M.D., Assistant Professor and senior attending physician at The Rockefeller University Hospital. “These findings make us more confident about the potential of targeting brown fat for therapeutic benefit.”
