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Category: engineering – Page 77

Crystal engineering is a green and convenient approach to designing desirable materials through rational manipulation of intermolecular interactions. We have reported the lesser reported sulfonate–pyridinium intermolecular interaction for the design and synthesis of organic co-crystals with improved features. Here in we report the utilization of the interaction to tune the solid-state luminescence of organic precursor naphthalene disulfonic acid (NDSA-2H). Organic salts of NDSA-2H are synthesized and characterized with three isostructural bipyridyl co-formers: 4-phenylpyridine (4-PhPy), 2-phenylpyridine (2-PhPy) and 2,2′-bipyridine (2,2-bpy). Structural investigation validates aggregation of organic acid and base co-formers through sulfonate–pyridinium synthon and proton transfer between them.

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It took Da Vinci 16 years to paint the Mona Lisa. Some say he needed 12 years just to paint her lips.

There is no truth to the rumors that slow Internet was the cause.

But Da Vinci, a polymath who dabbled in botany, engineering, science, sculpture, and geology as well as painting, surely would have appreciated a new text-to-image generative vision transformer developed by Google Research.

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Kairan Quazi announced the news in an impressive LinkedIn post, during which he explained how he’d begun his software engineering career at an early age.

While he kept post pretty professional, Quazi couldn’t help but gush about working for the ‘coolest company on the planet’.

Kairan Quazi is only in his teens, but has already graduated with a computer science degree before accepting a job with SpaceX.

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Cancer remains one of the leading causes of death in the US at over 600,000 deaths per year. Cancers that form solid tumors such as in the breast, brain, or skin are particularly hard to treat. Surgery is typically the first line of defense for patients fighting solid tumors. But surgery may not remove all , and leftover cells can mutate and spread throughout the body. A more targeted and wholistic treatment could replace the blunt approach of surgery with one that eliminates cancer from the inside using our own cells.

Dennis Discher, Robert D. Bent Professor of Chemical and Biomolecular Engineering, and postdoctoral fellow Larry Dooling provide a new approach in targeted therapies for solid tumor cancers in their study, published in Nature Biomedical Engineering. Their therapy not only eliminates cancerous cells, but teaches the to recognize and kill them in the future.

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Scientists have taken a significant step forward in the study of the properties of quarks and gluons, the particles that make up atomic nuclei, by resolving a long-standing issue with a theoretical calculation method known as “axial gauge.” MIT

MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT’s impact includes many scientific breakthroughs and technological advances. Their stated goal is to make a better world through education, research, and innovation.

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The experiments are the first of their kind and could lead to new advances in computing.

A team at the University of Chicago.

Founded in 1,890, the University of Chicago (UChicago, U of C, or Chicago) is a private research university in Chicago, Illinois. Located on a 217-acre campus in Chicago’s Hyde Park neighborhood, near Lake Michigan, the school holds top-ten positions in various national and international rankings. UChicago is also well known for its professional schools: Pritzker School of Medicine, Booth School of Business, Law School, School of Social Service Administration, Harris School of Public Policy Studies, Divinity School and the Graham School of Continuing Liberal and Professional Studies, and Pritzker School of Molecular Engineering.

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The latest recruit at SpaceX is a software engineer who passed its “technically challenging” and “fun” interview process.

What’s different about Kairan Quazi is that he’s just 14 years old.

He said in a LinkedIn post on Thursday: “I will be joining the coolest company on the planet as a software engineer on the Starlink engineering team. One of the rare companies that did not use my age as an arbitrary and outdated proxy for maturity and ability.”

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Year 2021 😗😁

MIT engineers, in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow tiny replicas of the pancreas, using either healthy or cancerous pancreatic cells. Their new models could help researchers develop and test potential drugs for pancreatic cancer, which is currently one of the most difficult types of cancer to treat.

Using a specialized gel that mimics the extracellular environment surrounding the pancreas, the researchers were able to grow pancreatic “organoids,” allowing them to study the important interactions between pancreatic tumors and their environment. Unlike some of the gels now used to grow tissue, the new MIT gel is completely synthetic, easy to assemble and can be produced with a consistent composition every time.

“The issue of reproducibility is a major one,” says Linda Griffith, the School of Engineering Professor of Teaching Innovation and a professor of biological engineering and mechanical engineering. “The research community has been looking for ways to do more methodical cultures of these kinds of organoids, and especially to control the microenvironment.”

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Year 2019 😗😁

Hepatology and drug development for liver diseases require in vitro liver models. Typical models include 2D planar primary hepatocytes, hepatocyte spheroids, hepatocyte organoids, and liver-on-a-chip. Liver-on-a-chip has emerged as the mainstream model for drug development because it recapitulates the liver microenvironment and has good assay robustness such as reproducibility. Liver-on-a-chip with human primary cells can potentially correlate clinical testing. Liver-on-a-chip can not only predict drug hepatotoxicity and drug metabolism, but also connect other artificial organs on the chip for a human-on-a-chip, which can reflect the overall effect of a drug. Engineering an effective liver-on-a-chip device requires knowledge of multiple disciplines including chemistry, fluidic mechanics, cell biology, electrics, and optics.

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