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A fter schools shifted to an online teaching mode, 17-year-old Nisha Pathak was worried about her increase in screen time. To avoid spending too much time looking at computers and to keep herself active, the Class 12 student of Neeraja Modi school, Jaipur, Rajasthan, took up farming.

“I wanted to keep myself engaged in activities that did not require looking at a screen. Apart from that, I wanted to grow the veggies and distribute them to underprivileged families living near my home,” says Nisha, adding that she learnt how to prepare seeds and plant them from a gardener in her community premises.

Initially, she grew vegetables like potatoes, onions and tomatoes. The harvest was distributed among underprivileged families who were living in neighbouring areas and were unable to procure fresh vegetables regularly.

The Virus Zoo is my latest educational blog post! I’ve written up ~1 page ‘cheat sheets’ on the molecular biology of specific viruses. I cover genome, structure, and life cycle. So far, my zoo includes adeno-associated virus (AAV), adenovirus, and herpes simplex virus 1 (HSV-1). However, I plan to add more viruses as time goes on! Some others I would like to incorporate later are coronavirus, HIV, anellovirus, lentivirus, ebolavirus, and MS2 bacteriophage. Feel free to suggest other interesting viruses in the comments! All images were created by me. #virology #molecularbiology #biotechnology #genetherapy #virus #biochemistry #genetics


Genome and Structure:

AAV genomes are about 4.7 kb in length and are composed of ssDNA. Inverted terminal repeats (ITRs) form hairpin structures at ends of the genome. These ITR structures are important for AAV genomic packaging and replication. Rep genes (encoded via overlapping reading frames) include Rep78, Rep68, Rep52, Rep40.1 These proteins facilitate replication of the viral genome. As a Dependoparvovirus, additional helper functions from adenovirus (or certain other viruses) are needed for AAVs to replicate.

AAV capsids are about 25 nm in diameter. Cap genes include VP1, VP2, VP3 and are transcribed from overlapping reading frames.2 The VP3 protein is the smallest capsid protein. The VP2 protein is the same as VP3 except that it includes an N-terminal extension with a nuclear localization sequence. The VP1 protein is the same as VP2 except that it includes a further N-terminal extension encoding a phospholipase A2 (PLA2) that facilitates endosomal escape during infection. In the AAV capsid, VP1, VP2, and VP3 are present at a ratio of roughly 1:1:10. It should be noted that this ratio is actually the average of a distribution, not a fixed number.

With our brand new documentary premiering at #SIGGRAPH 2022, you’ll get to take a look behind the scenes of the 2022 Spring GTC and discover how NVIDIA’s creative, engineering, and research teams pushed the limits of NVIDIA GPUs, AI, USD, and @NVIDIA Omniverse to deliver our most watched GTC ever.

Global Documentary Premiere: Wednesday, August 10, at 10:00 a.m. PT

Add the event to your calendar: https://nvda.ws/3z9kltq

Back in March this year, a study published in Evolutionary Biology claimed that fossils categorized as Tyrannosaurus rex represent three separate species. However, a new study published on July 25 in Evolutionary Biology refutes this claim and suggests that the previous research lacked evidence and Tyrannosaurus rex is made of only one species.

The previously controversial research implied that T. rex should be reclassified as three different species, including the standard T. rex, the bulkier “T. imperator,” and the slimmer “T. regina.” Researchers analyzed 38 T. rex fossils that contained leg bones and teeth samples, a press release revealed.

However, paleontologists at the American Museum of Natural History and Carthage College were determined to review the data of the previous research, adding data points from 112 species of living dinosaurs—birds—and from four non-avian theropod dinosaurs.

— Energy Info


Media Contact: Jennifer Kalez

SALEM – A public partnership with the Oregon Department of Energy, Oregon Department of Land Conservation & Development, Oregon State University’s Institute for Natural Resources, and the U.S. Department of Defense has published new educational materials that will help local governments, Tribes, communities, policymakers, agencies, energy developers, and other stakeholders access important information and considerations for potential renewable energy in Oregon.

The Oregon Renewable Energy Siting Assessment (ORESA) project was funded through a $1.1 million U.S. Department of Defense (DoD) grant, with the goal of providing baseline data to support important conversations around potential energy and transmission development in the state.

Researchers from MIT

MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT’s impact includes many scientific breakthroughs and technological advances. Their stated goal is to make a better world through education, research, and innovation.