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Category: education – Page 89

The concept of Transhumanism has been around for a long time, but it actually looks like it’s starting to happen. In today’s video, we will look at how humans are already merging with machines and what will come next. IPhone wireless charging cases — https://amzn.to/3bz0oRg.
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A team of researchers led by Yale University.

Established in 1,701, Yale University is a private Ivy League research university in New Haven, Connecticut. It is the third-oldest institution of higher education in the United States and is organized into fourteen constituent schools: the original undergraduate college, the Yale Graduate School of Arts and Sciences and twelve professional schools. It is named after British East India Company governor Elihu Yale.

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JPL & the Space Age: To the Rescue.

In 1990, Hubble meant trouble. The highly touted space telescope was designed to escape Earth’s blurry atmosphere to capture unparalleled visual images of the universe, but its creators were shocked to discover that a minuscule flaw rendered it nearsighted.

Enter NASA’s Jet Propulsion Laboratory scientists and engineers, who offered up an ingenious solution to Hubble’s visual woes. But would it work?

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The chief inspector of schools in England has told parliament that children’s rights should take priority over religious concerns and schoolgirls should be free from pressure to wear hijabs.

The National Secular Society has welcomed the remarks from Ofsted chief inspector Amanda Spielman, which came in an appearance before the Commons public accounts committee on Wednesday.

Spielman defended a recent assertion that schools should enforce “muscular liberalism” and said religion should not “get priority over all the other protected characteristics”, referring to anti-discrimination protections in equalities legislation.

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I have created an educational guide to the adenovirus capsid! The adenovirus is one of the most frequently used types of viruses for gene therapy (along with AAV and lentivirus). It is a powerful vehicle for delivering DNA to cells in the body. But to work with adenovirus as a technology, it is important to understand its fundamental biological structure and function. This guide will help you to gain a more holistic comprehension of a particularly important part of adenovirus biology: the capsid. I made the images using PyMol.

PDF version: Guide to the Structure and Function of the Adenovirus Capsid

For this guide, I will explain the fundamental biology of adenovirus capsid proteins with an emphasis on the context of gene therapy. While the guide is meant primarily for readers with an interest in applying adenovirus to gene therapy, it will not include much discussion of the techniques and technologies involved in engineering adenoviruses for such purposes. If you are interested in learning more about adenovirus engineering, you may enjoy my review paper “Synthetic Biology Approaches for Engineering Next-Generation Adenoviral Gene Therapies” [1]. Here, I will focus mostly on the capsid of human adenovirus serotype 5 (Ad5) since it is the most commonly used type of adenovirus employed in gene therapy research, but I will occasionally describe other types of adenoviruses when necessary. Many of the presented concepts remain the same or similar across other types of adenoviruses.

The adenovirus consists of an icosahedral protein capsid enclosing a double-stranded DNA (dsDNA) genome. It possesses 12 fiber proteins which protrude from the capsid and helps to facilitate cellular transduction. Adenoviruses are nonenveloped and approximately 90 nm in diameter (not including the fibers). The Ad5 genome is about 36 kb in size. Major capsid proteins of the adenovirus include the hexon, penton, and fiber. The minor capsid proteins are protein IIIa, protein VI, protein VIII, and protein IX. Inside the capsid, there are core proteins including protein V, protein VII, protein μ (also known as protein X), adenovirus proteinase (AVP), protein IVa2, and terminal protein (TP) [2].

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Thomas Fuller, an African sold into slavery in 1,724 at age 14, was sometimes known as the “Virginia Calculator” for his extraordinary ability to solve complex mathematical problems in his head. He was asked how many seconds there were in a year, he briefly answered 31,536,000 seconds.

He was asked again how many seconds a man who is 70 years old, 17 days and 12 hours lived, he answered in a minute and a half 2,210,500,800. One of the men was doing the problems on paper and informed Fuller that he was wrong because the answer was much smaller. Fuller hastily responded, “Nah, you forgot about leap years. When leap years were added to the account, the sums matched up.”

Fuller was one of the first cases recorded in the literature of the wise man syndrome, when in 1,789, Benjamin Rush, the father of American psychiatry, described his incredible ability to calculate, without having an education and training in mathematics, his ability was used as proof that enslaved African Americans were equal to whites in intelligence, fueling some pro-abolitionist discussions.

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US-based architecture studio NBBJ has released designs for a net-zero school in Encino, California, that will cater to neurodiverse students.

The design of the Lower School campus of Westmark School uses acoustic technologies, as well as the integration of flora and natural materials, to create a comfortable environment for students with special needs.

“Designers selected a variety of sound-absorbing materials for different spaces, developed reading nooks and other niches for creative learning both inside and outside the classroom, and oriented views to green space to enhance different educational modes,” said NBBJ.

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