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Cancer cells use a bizarre strategy to reproduce in a tumor’s low-energy environment; they mutilate their own mitochondria! Researchers at Cold Spring Harbor Laboratory (CSHL) also know how this occurs, offering a promising new target for pancreatic cancer therapies.

Why would a cell want to destroy its own functioning mitochondria? “It may seem pretty counterintuitive,” admits M.D.-Ph. D. student Brinda Alagesan, a member of Dr. David Tuveson’s lab at CSHL.

According to Alagesan, the easiest way to think about why may do this is to think of the mitochondria as a powerplant. “The mitochondria is the powerhouse of the cell,” she recites, recalling the common grade school lesson. And just like a traditional powerplant, the mitochondria create their own pollution.

I’m super excited to share this new Quartz article of mine, part of an ongoing personal debate about #transhumanism, #kids, and #education in my family:


But the age of downloading experience and expertise directly into our brain mainframe is coming. So is downloading professional training, including everything from becoming a police officer to practicing medicine or investigative journalism.

For many in the audience, I think that was the first time considering this could become a reality in our lifetime.

But in plenty of instances, brainwave tech is already here. People fly drones using mind-reading headsets. Parkinson’s disease patients can use brain chips to calm shaking attacks. Machine interfaces let people silently communicate mind-to-mind with one another, or with devices.

China isn’t the only country with a draconian “social credit score” system — there’s one quite a bit like it operating in the U.S. Except that it’s being run by American businesses, not the government.

There’s plenty of evidence that retailers have been using a technique called “surveillance scoring” for decades in which consumers are given a secret score by an algorithm to give them a different price — but for the same goods and services.

But the practice might be illegal after all: a California nonprofit called Consumer Education Foundation (CEF) filed a petition yesterday asking for the Federal Trade Commission (FTC) to look into the shady practice.

Dr. Alan Green’s patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives.

Over the past two years, more than 200 patients have flocked to see Green after learning that two drugs he prescribes could possibly stave off aging. One 95-year-old was so intent on keeping her appointment that she asked her son to drive her from Maryland after a snowstorm had closed the schools.

Green is among a small but growing number of doctors who prescribe drugs “off-label” for their possible anti-aging effects. Metformin is typically prescribed for diabetes, and rapamycin prevents organ rejection after a transplant, but doctors can prescribe drugs off-label for other purposes — in this case, for “aging.”

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Are you prepared for the Age of Machine Intelligence? That’s a time when machines anticipate consumers’ choices before they are made. That age is nearer than many people realize, according to author/futurist Mike Walsh, who said business leaders need to understand how the new reality impacts the decisions they make.

The National Automatic Merchandising Association show, held last week in Las Vegas, made an appropriate setting for Walsh’s message, given the number of exhibits and education sessions featuring artificial intelligence. While these new technologies impact many industries, the convenience services industry has experienced a significant boost in recent years thanks to AI, micro markets, cashless readers, digital signage, telemetry-based remote machine monitoring, smart sensor shelving, facial detection and voice technology.

Walsh, author of “The Dictionary of Dangerous Ideas” and CEO of Tomorrow, a consumer innovation research lab, challenged his listeners during his keynote presentation to think more creatively.

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Artificial Intelligence (AI) is a field that has a long history but is still constantly and actively growing and changing. Artificial Intelligence (AI) technology is increasingly prevalent in our everyday lives. It has uses in a variety of industries from gaming, journalism/media, to finance, as well as in the state-of-the-art research fields from robotics, medical diagnosis, and quantum science.


Udacity was born out of a Stanford University experiment in which Sebastian Thrun and Peter Norvig offered their “Introduction to Artificial Intelligence” course online to anyone, for free. Over 160,000 students in more than 190 countries enrolled and not much later, Udacity was born.

Udacity, a pioneer in online education, is building “University by Silicon Valley”, a new type of online university that: – teaches the actual programming skills that industry employers need today; – delivers credentials endorsed by employers, because they built them; – provides education at a fraction of the cost and time of traditional schools.

David A. Sinclair, Ph.D., A.O. is an Australian biologist and a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is best known for his work on understanding why we age and how to slow its effects. He obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney, and received the Australian Commonwealth Prize. In 1995, he received a Ph.D. in Molecular Genetics then worked as a postdoctoral researcher at the Massachusetts Institute of Technology with Leonard Guarente. Since 1999 he has been a tenured professor in the Genetics Department of Harvard Medical School.

Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging. His work is featured in five books, two documentary movies, 60 Minutes, Morgan Freeman’s “Through the Wormhole” and other media.

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