Gas accidents such as toxic gas leakage in factories, carbon monoxide leakage of boilers, or toxic gas suffocation during manhole cleaning continue to claim lives and cause injuries. Developing a sensor that can quickly detect toxic gases or biochemicals is still an important issue in public health, environmental monitoring, and military sectors. Recently, a research team at POSTECH has developed an inexpensive, ultra-compact wearable hologram sensor that immediately notifies the user of volatile gas detection.
[Professor Junsuk Rho’s research team at POSTECH develops wearable gas sensors that display instantaneous visual holographic alarm.].
This benefits customers by accelerating access to future vehicles that feature the latest technology while also enabling their current vehicles to be eligible to receive updates and improvements over time—unlocking additional value beyond the initial point of purchase. And for large enterprises, shorter development cycles with less ground-up engineering can equate to significant cost savings and allow more investment in innovation.
Beyond vehicles themselves, the tools, techniques and processes that are required to engineer and manufacture at scale are also benefitting from developments in the latest hardware technology. Advancements in raw material chemistry and processing, fabrication and physical sciences are leading to lighter, stronger and better-performing vehicle applications in parallel with greater connectivity.
As advancements in transportation technology continue to evolve, it’s important for companies to balance their focus on the continual development of both hardware and software technologies. Forgoing advancements in one without investing in the development of the other can lead to significant risks and missed opportunities for long-term success.
Synthetic cells are a versatile technology with the potential to serve as smart delivery devices or as chassis for creating life from scratch. Despite the development of new tools and improvements in synthetic cell assembly methods, the biological parts used to regulate their activity have limited their reach to highly controlled laboratory environments12. In the field’s preliminary work, well-established arabinose and IPTG-inducible transcription factors and theophylline-responsive riboswitches were used to control in situ gene expression5,6. Still, each performed poorly in vitro and represented a leaky, insensitive route of transcription/translation control. Later, the transition to AHSL-sensitive transcription factors afforded synthetic cells the ability to sense and produce more biologically useful QS molecules, which are central to coordinating collective bacterial behaviors. Although this marked considerable progress toward integrating synthetic cells with living cells, the most frequently adopted QS systems used to date, LuxR/LuxI and EsaR/EsaI, recognize and synthesize the same AHSL (3OC6-HSL), limiting the variety of synthetic cell activators that work orthogonally5,7,10,11.
In this work, we diverged from using naturally derived parts to control gene expression, instead utilizing chemically modified LA-DNA templates to tightly and precisely control the location of synthetic cell activation with UV light. This LA-DNA approach was subsequently implemented to regulate communication with E. coli cells using the BjaI/BjaR QS system, adding this unique branched AHSL into the synthetic cell communication toolbox. We believe this system is ideally suited to synthetic cell communication. It couples an acyl-CoA-dependent synthase, BjaI, which efficiently synthesizes IV-HSL from its commercially available substrates, IV-CoA and SAM, with a highly sensitive IV-HSL-dependent transcription factor, BjaR, that activates gene expression at picomolar concentrations of IV-HSL.
Some transcription factors are known as master regulators, and they can have an impact on many different biochemical pathways and processes in cells. | Cell And Molecular Biology.
Almost half of the tap water in the US is contaminated with chemicals known as “forever chemicals,” according to a new study from the US Geological Survey.
The number of people drinking contaminated water may be even higher than what the study found, however, because the researchers weren’t able to test for all of these per-and polyfluorinated alkyl substances, or PFAS, chemicals that are considered dangerous to human health. There are more than 12,000 types of PFAS, according to the National Institutes of Health, but this study looked at only 32 of the compounds.
One of the greatest challenges facing the future of clean nuclear energy is scientists’ ability to recover heavy metals from nuclear waste, such as lanthanides and actinides. A new computational tool could help chemists design ligands to selectively bind valuable metals in organometallic complexes.
Nuclear waste contains a smorgasbord of elements from across the periodic table, including transition metals, lanthanides, and actinides. Ideally, scientists would like to reduce the amount of waste generated from nuclear reactors by separating out elements that could be repurposed elsewhere. To tackle these tricky chemical separation techniques, chemists often start with 3D structural models to design ligands that can selectively bind the desired metal to form an organometallic complex that can later be isolated.
Though researchers working with d-block organometallics have an arsenal of structural prediction tools at their disposal, there are no resources available to do the same for the full range of lanthanide and actinide complexes. That’s partly because these f-block elements can form higher coordinate complexes with ligands compared to d-block transition metals, according to Ping Yang and Michael G. Taylor, computational chemists at Los Alamos National Laboratory.
Researchers have developed a metallic gel that is highly electrically conductive and can be used to print three-dimensional (3D) solid objects at room temperature. The paper, “Metallic Gels for Conductive 3D and 4D Printing,” has been published in the journal Matter.
“3D printing has revolutionized manufacturing, but we’re not aware of previous technologies that allowed you to print 3D metal objects at room temperature in a single step,” says Michael Dickey, co-corresponding author of a paper on the work and the Camille & Henry Dreyfus Professor of Chemical and Biomolecular Engineering at North Carolina State University. “This opens the door to manufacturing a wide range of electronic components and devices.”
To create the metallic gel, the researchers start with a solution of micron-scale copper particles suspended in water. The researchers then add a small amount of an indium-gallium alloy that is liquid metal at room temperature. The resulting mixture is then stirred together.
New research by the University of Liverpool could signal a step change in the quest to design the new materials that are needed to meet the challenge of net zero and a sustainable future.
Published in the journal Nature, Liverpool researchers have shown that a mathematical algorithm can guarantee to predict the structure of any material just based on knowledge of the atoms that make it up.
Developed by an interdisciplinary team of researchers from the University of Liverpool’s Departments of Chemistry and Computer Science, the algorithm systematically evaluates entire sets of possible structures at once, rather than considering them one at a time, to accelerate identification of the correct solution.
Dr. Robert Floyd, Ph.D. is Executive Secretary of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO — https://www.ctbto.org/), the organization tasked with building up the verification regime of the Comprehensive Nuclear-Test-Ban Treaty, a multilateral treaty opened for signature in 1996 by which states agree to ban all nuclear explosions in all environments, for military or civilian purposes.
Prior to joining CTBTO, Dr. Floyd was the Director General of the Australian Safeguards and Non-proliferation Office (ASNO), where he was responsible for Australia’s implementation of and compliance with various international treaties and conventions including the Comprehensive Nuclear-Test-Ban Treaty, Nuclear Non-Proliferation Treaty, Convention on the Physical Protection of Nuclear Material (CPPNM) and the Chemical Weapons Convention.
During his time as Director General of ASNO, Dr. Floyd also chaired the advisory group to the Director General of the International Atomic Energy Agency on safeguards implementation (SAGSI), co-chaired the Preparatory Committee for the review of the amended CPPNM, co-chaired one of the working groups of the International Partnership for Nuclear Disarmament Verification, was the lead official for Australia in the Nuclear Security Summit process, and chaired the Asia-Pacific Safeguards Network.
Prior to his appointment with ASNO, Dr. Floyd served for more than seven years in the Department of the Prime Minister and Cabinet where he held a number of senior executive positions providing advice to the Prime Minister on policy issues covering counter-terrorism, counter-proliferation, emergency management, and homeland and border security.
Dr. Floyd was awarded a commemorative medal on the 30th anniversary of Kazakhstan’s independence in recognition of the strong and enduring partnership between the CTBTO and Kazakhstan on nuclear non-proliferation, disarmament, peace, and security. Dr. Floyd also received the Australian Nuclear Association (ANA) award for 2021 in recognition of his outstanding leadership role as Director General of the ASNO.
With a Ph.D. in population ecology, Dr. Floyd spent the first 20 years of his career as a research scientist with the Commonwealth Scientific and Industrial Research Organization (CSIRO).
An engineered version of the mechanosensitive protein talin was used as a monomer in combination with a synthetic chemical crosslinker to form a hydrogel. This shock-absorbing material is shown to capture and preserve projectiles fired at 1.5 km s−1.
