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On Nov. 16, Mayo Clinic in Arizona was able to celebrate a first in this practice and transplanted a heart into a patient following the natural circulatory death of the donor.

“Mayo Clinic is the only one in Arizona to have used this new ‘heart in a box’ technology,” the hospital said.

With this advancement, donors will be able to give the gift of life much sooner than before. Thousands of people are awaiting heart transplants and sadly, many do die while waiting.

“The risk of developing ALCL is actually much lower than the risk of experiencing a relapse of breast cancer,” says lead author Connor J. Kinslow, MD, a resident in radiation oncology at the Columbia University Vagelos College of Physicians and Surgeons.

“Based on our findings, we do not believe that women should be dissuaded from having implant-based breast reconstruction after mastectomy solely due to the risk of ALCL.”

The new study was designed to provide women with accurate information about risk and is the first to look at rates of ALCL in breast cancer survivors who’ve had breast implants after mastectomy.

“Our goal is to re-regulate all of your genes back to an earlier state.” Excellent. Hurry please. I’m 51.


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Tumors affecting the central nervous system (CNS), either primary or secondary, are highly prevalent and represent an unmet medical need. Prognosis of these tumors remains poor, mostly due to the low intrinsic chemo/radio-sensitivity of tumor cells, a meagerly known role of the microenvironment and the poor CNS bioavailability of most used anti-cancer agents. The BBTB is the main obstacle for anticancer drugs to achieve therapeutic concentrations in the tumor tissues. During the last decades, many efforts have been devoted to the identification of modalities allowing to increase drug delivery into brain tumors. Until recently, success has been modest, as few of these approaches reached clinical testing and even less gained regulatory approval.

They discovered that removing PLD3 from neurons using gene therapy resulted in a significant decrease in axonal swelling.

A study on Alzheimer’s published recently by Yale University is quite attention-grabbing. Because the disease’s crippling symptoms could be brought on by swelling in the brain brought on by amyloid plaques, say the experts.

One of the main features of Alzheimer’s is the formation of amyloid plaques. Researchers have been trying to shrink these plaques in their researchers for years. In addition, Yale researchers have found that swelling caused by a byproduct of these plaques may be the cause of the disease’s debilitating symptoms.

Gravity could be a leading cause of irritable bowel syndrome, along with increased serotonin levels and changes in the gut microbiome.

Approximately 20 to 40 percent of all visits to gastroenterologists are due to irritable bowel syndrome (IBS) symptoms. The common disorder affects between 25 and 45 million people in the United States and up to ten percent of the world’s population, yet experts aren’t sure of how or why it develops.

However, there is no dearth of theories. While one explains that IBS is a gut-brain disorder, another theory states that IBS is caused by abnormalities in the gut microbiome.

The presence of food-specific IgA antibodies in the gut does not prevent peanut or egg allergies from developing in children, according to a Northwestern Medicine study published in Science Translational Medicine.

Scientists examined from more than 500 infants across the country and found that the presence of Immunoglobulin A, the most common antibody found in in the , does not prevent peanut or from developing later in life.

This discovery calls into question the role of Immunoglobulin A, or IgA, which was previously thought to be a protective factor against the development of food allergies.

A gene linked to autism spectrum disorders plays a critical role in early brain development and may shape the formation of both normal and atypical nerve connections in the brain, according to a new study by Weill Cornell Medicine investigators.

The study, published Nov. 28 in Neuron, employed a combination of sophisticated genetic experiments in mice and analysis of human brain imaging data to better understand why mutations in a gene called Gabrb3 are linked to a high risk of developing (ASD) and a related condition called Angelman Syndrome. Both conditions involve abnormal behaviors and unusual responses to sensory stimuli, which appear to stem, at least in part, from the formation of atypical connections between neurons in the brain.

Neuron al connections in the brain, and developmental synchronization of neuronal networks, are perturbed in individuals with , and there are that are implicated in the pathogenesis of ASD,” said co-first author Dr. Rachel Babij, a former student in the Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-Ph. D. program in the laboratory of Natalia De Marco García, an associate professor in the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine.

One of the world’s leading hospitals is preparing to offer longevity clinical services to patients. Sheba Medical Center in Tel Aviv, Israel, is poised to open a dedicated longevity centre in 2023, with the goal of democratising the extension of healthy lifespan for the masses.

Longevity. Technology: While research, development and investment in longevity are at an all-time high, the implementation of longevity clinical practice in mainstream healthcare is virtually non-existent. While private clinical practices are now making longevity services accessible to those who can afford it, the societal benefit of improving healthspan can only be realised if everyone can access it. To learn more, we caught up with Professor Tzipi Strauss, Director of Neonatology at Sheba Hospital, who is the driving force behind the new centre.

It may seem curious that a paediatrician is the instigator of an initiative focused on improving aging, but Strauss explains that the relevance of longevity begins at birth.