Lifeboat Foundation

Technique allows researchers to toggle on individual genes that regulate cell growth, development, and function.

By combining CRISPR technology with a protein designed with artificial intelligence, it is possible to awaken individual dormant genes by disabling the chemical “off switches” that silence them. Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports.

The approach will allow researchers to understand the role individual genes play in normal cell growth and development, in aging, and in such diseases as cancer, said Shiri Levy, a postdoctoral fellow in UW Institute for Stem Cell and Regenerative Medicine (ISCRM) and the lead author of the paper.

NVIDIA today introduced Clara Holoscan MGX™, a platform for the medical device industry to develop and deploy real-time AI applications at the edge, specifically designed to meet required regulatory standards.

Regardless of Pandemics, Wars, Supply chain shocks…the Planets digital brain capacity continues its near exponential growth.

When added to the 728 hyperscale datacentres that were in operation at the end of 2021 and factoring in [the] many new datacentre plans that will be announced over the next two to three years, we forecast that by the end of 2026 there will be an installed base of nearly 1,200 hyperscale datacentres around the world.

“Almost 40% of the world’s operational hyperscale datacentres are located in the US, and the bulk of the developments in the pipeline will also be US-based, with China and Ireland name-checked as the second and third countries with the most new builds planned.” The future looks bright for hyperscale operators, with double-digit annual growth in total revenues supported in large part by cloud revenues that will be growing in the 20–30% per year range,”

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To accurately diagnose and treat diseases, doctors and researchers need to see inside bodies. Medical imaging tools have come a long way since the humble X-ray, but most existing tools remain too coarse to quantify numbers or specific types of cells inside deep tissues of the body.

Pfizer has issued a nationwide recall of some blood pressure medications due to the presence of nitrosamine above the Acceptable Daily Intake (ADI) level.

A team of researchers from Harvard Medical School and Boston Children’s Hospital has developed a device to help patients experiencing refractory hypoxemia. In their paper published in Proceedings of the National Academy of Sciences, the group describes their new device and how well it worked when tested on human blood and blood inside of live rats.

Refractory hypoxemia is a condition sometimes experienced by patients on ventilators—it is generally due to acute respiratory distress syndrome. Less oxygen makes the trip from the lungs into the bloodstream, leading to organ damage and sometimes death. Current treatment often involves the use of an extracorporeal membrane oxygenation (ECMO) machine. It extracts most of a patient’s blood, removes carbon dioxide, adds oxygen and then pumps it back into the patient. Because ventilators can damage lungs, and because access to ECMO machines is limited (and risk of infection is high), the researchers developed a new machine that can add oxygen directly to blood while it is still inside the patient.

The new machine works by first infusing oxygen into a liquid solution. That solution travels through a series of ever-smaller nozzles, reducing the size of the bubbles down to micron scale. The bubbles, the researchers note, are smaller than red blood cells. Next, the bubbles get a coating of a lipid membrane that is similar to some types of natural cell membranes. This prevents toxicity and also keeps the bubbles from sticking together. The resulting solution is then injected directly into a patient’s bloodstream. Once inside, the lipids dissolve, releasing the oxygen into the bloodstream. They are tiny enough that they will not block any blood vessels.

Osso VR, the VR surgical training platform, today announced it’s closed a $66 million Series C financing round, something the company says will be used to broaden its VR surgical offering and hire more expert talent.

The Series C round was led by Oak HC/FT, which includes participation from Signalfire, GSR Ventures, Tiger Global Management and Kaiser Permanente Ventures.

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The father of the GIF passes away at the age of 74 after contracting COVID-19.

Summary: Oleic acid produced in the brain is an essential regulator of processes that enable memory, learning, and mood regulation. Oleic acid, which is abundant in olive oil, also promoted neurogenesis and increases cell proliferation.

Source: Baylor College of Medicine.

Many people dread experiencing the cognitive and mood declines that often accompany reaching an advanced age, including memory disorders such as Alzheimer’s disease and mood conditions like depression.