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Category: biotech/medical – Page 767

The bioactivity of most near-infrared II (NIRII) fluorophores are limited, thereby conflicting the achievement of strong fluorescence and high catalytic activities, due to a lack of free electrons in the method.

To overcome this challenge, Huizhen Ma and a research team in translational medicine, , physics, and materials at the Tianjin University China developed atomically precise gold clusters with strong near-infrared II fluorescence to show potent enzyme-mimetic activities by using atomic engineering, to form active copper single-atom sites.

These gold-copper clusters (Au21 Cu1) showed higher antioxidant nature with a 90-fold catalase-like and 3-fold higher superoxide dismutase-like activity compared to gold clusters alone. These clusters can be cleared through the to monitor cisplatin-induced within a 20–120-minute window to visualize the process in 3D via near-infrared light-sheet microscopy.

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The successful transfer of a gene that produces HMW-HA paves the way for improving the health and lifespan of humans, too. In a groundbreaking endeavor, scientists at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, leading to enhanced health and increased lifespan. Naked mole rats, noted for their resistance to age-related diseases, have a gene that produces high molecular weight hyaluronic acid (HMW-HA), which when introduced to mice, demonstrated potential anti-aging benefits.

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The battery can be charged for up to 200 cycles and does not contain wires or toxic heavy metals.

Researchers at the Nanyang Technological University (NTU) in Singapore have devised a micrometer-thin battery that can power smart contact lenses and be charged with tears, a university press release said.

Contact lenses have long been used for vision correction. With technological advancements, companies have been working to make smarter versions, connecting to devices like smartphones and displaying information close to the wearer’s eyes. Such applications require the lenses to have an internal battery.

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Ever since the Jerry Lewis telethons began in the 1960s, millions of people have become familiar with an otherwise rare disease called muscular dystrophy (MD).

The medical world has learned much over the ensuing years, including that more than 30 closely related disorders exist that can produce the gradual muscle degeneration that steals a child’s ability to walk and eventually disrupts other organ functions. An estimated 250,000 people in the U.S. are living with a muscular dystrophy. While many are living longer lives thanks to improved treatments, no cure has been found.

Now an eye-opening study led by scientists at Cincinnati Children’s—published Aug. 25, 2023, in Science Advances —reports an entirely new approach to preventing the muscle-wasting symptoms of MD. The research focuses on the role played by mitochondria, the tiny organelle within our cells that processes nutrients into the energy cells need to survive.

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So past the 7 minute mark we see a competing interest may have stumbled upon the same thing so Katcher and gang are starting a company to commercialize E5.

Here we review a preprint from Dr Katcher and Dr Horvath giving more detail on the experiments which showed a 54% epigenetic rejuvenation in rats and reveals the source of E5 and the processing involved.

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00:00 Review of paper.

Continue reading “The Identity Of E5 Revealed | Reduced Epigenetic Age By More Than 50%” | >

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In this episode, filmed during Abundance360, Peter and David discuss David’s groundbreaking research on reversing aging through epigenetic changes, emphasizing that aging is not just damage to the body but a loss of information. They talk about age reversal as a possibility, rejuvenating brains, and regaining lost memories.

David Sinclair is a biologist and academic known for his expertise in aging and epigenetics. Sinclair is a genetics professor and the Co-Director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research. He’s been included in Time100 as one of the 100 Most Influential People in the World, and his research has been featured all over the media. Besides writing a New York Times Best Seller, David has co-founded several biotech companies, a science publication called Aging, and is an inventor of 35 patents.

Read Sinclair’s latest study, Chemically Induced Reprogramming to Reverse Cellular Aging: https://www.aging-us.com/article/204896/text.

Learn about Abundance360: https://www.abundance360.com/

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Continue reading “Aging is Now Optional w/ David Sinclair | EP #60” | >

Goldbeating, an age-old craft pioneered by ancient Egyptian artisans more than five millennia ago, involves the meticulous thinning of bulk gold into gossamer-like leaves. Throughout history, this intricate process has adorned various masterpieces, such as the tombs of Thebes and Saqqara, and has cemented its place in art and adornments across cultures. Today, nanoscale gold is used not only for decorating fancy desserts, but is indispensable for modern applications ranging from microelectronics to nanomedicine.

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Human Immortality — If you thought Human Immortality was just a concept in science fiction, this episode reveals how it will become science fact. For some scientists featured in this program, achieving Immortality is not a question of ‘If’. The real question is ‘When?’.

Human Immortality (2022)
Director: Emma Watts.
Writers: Kyle McCabe, Christopher Webb Young.
Stars: Samantha Brady, Aubrey DeGrey, Leonard Guarente.
Genre: Documentary.
Country: United States.
Language: English.
Release Date: August 31, 2022 (United States)

Synopsis:
If you thought Human Immortality was just a concept in science fiction, this episode reveals how it will become science fact. For some scientists featured in this program, achieving Immortality is not a question of ‘If’. The real question is ‘When?’.

One scientist shows how she is making lab-grown organs called ‘ghost hearts’ that not only grow quickly, but that can be accepted in any host’s body without rejection—ending the agony for those waiting for organ transplants. Another biologist is looking at Immortality at the microbiological level. In his lab, he’s identified the ‘longevity gene’ (called SIR2) that can slow the ageing process, and which holds the key that will unlock our ability to better control the rate at which we age. One gerontologist is unearthing the immortal secrets of lobsters, who never stop growing and naturally live up to the astonishing age of 122 years. Inspired by how their bodies regulate cellular division, he’s developing cutting-edge medications that will boost human longevity.

Incredibly, one pioneer is creating a unique medical cocktail that can even reverse ageing. Medical techniques like these could pave the way to Human Immortality.

MORE DOCS!

Continue reading “Human Immortality | Life Extension | Advancements in Science” | >

This post is also available in: he עברית (Hebrew)

Important computer systems at hospitals and clinics have been offline for over two weeks after a cyberattack forced emergency room shutdowns and ambulance diversions. According to Prospect Medical Holdings, progress is being made “to recover critical systems and restore their integrity,” but the company, which runs 16 hospitals and dozens of other medical facilities in various states could not say when operations will return to normal.

The recovery process for this situation can often take weeks, and in the meantime, hospitals are reverting to paper systems and people to monitor equipment, run records between departments, and do other tasks that are usually electronic.

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